Otolaryngology Case Reports最新文献_第6页

Diffuse large B-cell lymphoma - an unusual cause of a rapidly enlarging thyroid mass: A large case series 弥漫性大b细胞淋巴瘤——甲状腺肿块迅速增大的一种罕见病因：一个大病例系列

IF 0.3

Otolaryngology Case Reports Pub Date : 2025-09-01 Epub Date: 2025-08-08 DOI: 10.1016/j.xocr.2025.100686

Lauren M. Boeckermann , Nikhil Bellamkonda , Hilary McCrary , Devaprabu Abraham , Jason P. Hunt

{"title":"Diffuse large B-cell lymphoma - an unusual cause of a rapidly enlarging thyroid mass: A large case series","authors":"Lauren M. Boeckermann , Nikhil Bellamkonda , Hilary McCrary , Devaprabu Abraham , Jason P. Hunt","doi":"10.1016/j.xocr.2025.100686","DOIUrl":"10.1016/j.xocr.2025.100686","url":null,"abstract":"<div><h3>Introduction</h3><div>Presentation of a rapidly enlarging thyroid mass (RETM) typically elicits concern for anaplastic thyroid carcinoma (ATC). However, primary thyroid lymphoma (PTL), specifically diffuse large B-cell lymphoma (DLBCL), has a similar clinical presentation and should be considered in the initial differential diagnosis as they can quickly alter clinical work-up and management.</div></div><div><h3>Case presentation</h3><div>This is a single institution case series of two years, 2022–2024, of six patients (Five males and one female, aged 63–90 years old) with RETM with biopsy proven DLBCL. Four patients had history of hypothyroidism. Three patients presented to the emergency department for worsening dyspnea and dysphagia while three were seen outpatient with milder symptoms such as dysphonia or dysphagia. Definitive diagnosis of DLBCL was determined by fine needle aspiration, core, or excisional biopsy. Consideration of ATC was evaluated with onsite cytology review and BRAF testing by pyrosequencing. The subtypes of DLBCL varied; three were identified as germinal center subtype, one was activated B-cell subtype, and the remaining two cases were unspecified. Various treatments were initiated including R-CHOP, mini-R-CHOP, Pola-R-CHOP, and R-CEOP in addition to airway stabilization measures.</div></div><div><h3>Discussion</h3><div>Primary thyroid lymphomas, specifically DLBCL, are an uncommon cause of RETM. Like ATC, they can present with progressive symptoms of dyspnea, dysphagia, and dysphonia secondary to local tissue invasion and mass effect.</div></div><div><h3>Conclusion</h3><div>This case series demonstrates the importance of sending initial pathology for lymphoma work up, especially given a history of hypothyroidism, in addition to typical cytopathology and BRAF testing for ATC for RETM.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"36 ","pages":"Article 100686"},"PeriodicalIF":0.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144826913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary squamous cell carcinoma of the lung with metastasis to the parotid gland in a never-smoking patient: A rare case report 从不吸烟的原发性肺鳞状细胞癌伴腮腺转移：一例罕见病例报告

IF 0.2

Otolaryngology Case Reports Pub Date : 2025-09-01 Epub Date: 2025-07-13 DOI: 10.1016/j.xocr.2025.100673

Adam Karkoutli , Nikhil Bellamkonda , Kathleen C. Kerrigan , Hilary C. McCrary

{"title":"Primary squamous cell carcinoma of the lung with metastasis to the parotid gland in a never-smoking patient: A rare case report","authors":"Adam Karkoutli , Nikhil Bellamkonda , Kathleen C. Kerrigan , Hilary C. McCrary","doi":"10.1016/j.xocr.2025.100673","DOIUrl":"10.1016/j.xocr.2025.100673","url":null,"abstract":"<div><h3>Background</h3><div>Metastasis to the parotid gland from non-small cell lung cancer (NSCLC) is extremely rare, particularly in non-smoking patients. This case underscores diagnostic challenges and the importance of molecular testing in identifying the primary malignancy.</div></div><div><h3>Methods</h3><div>A 48-year-old male with no smoking history presented with persistent cough, dyspnea, fatigue, and a parotid mass concerning for squamous cell carcinoma (SCC) on biopsy. Imaging revealed a right lower lobe intrapulmonary mass, also confirmed as SCC, creating ambiguity about the primary malignancy. When parotidectomy was performed, tissue was obtained for next-generation sequencing, which revealed an ROS1 fusion, confirming the pulmonary source.</div></div><div><h3>Results</h3><div>Identification of an ROS1 fusion confirmed NSCLC as the primary malignancy. The patient was started on ROS1-targeted therapy, resulting in disease stabilization.</div></div><div><h3>Conclusions</h3><div>This case highlights the importance of molecular diagnostics in guiding therapy and confirms that metastatic lung cancer should be considered in cases of parotid malignancies with atypical presentations.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"36 ","pages":"Article 100673"},"PeriodicalIF":0.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Idiopathic Frey's syndrome of the external auditory canal: A case report with a literature review 外耳道特发性弗雷氏综合征1例并文献复习

IF 0.3

Otolaryngology Case Reports Pub Date : 2025-09-01 Epub Date: 2025-07-23 DOI: 10.1016/j.xocr.2025.100679

Yasser AL-Ghabra , Ahmed Alkheder , Mohammed Hamdi , Abdulmajeed Yousfan

引用次数: 0

Bilateral choanal atresia in an adult: a rare case report and a literature review 成人双侧后肛门闭锁一例罕见病例报告及文献复习

IF 0.2

Otolaryngology Case Reports Pub Date : 2025-09-01 Epub Date: 2025-07-15 DOI: 10.1016/j.xocr.2025.100677

Yasser Al-Ghabra, Alia Issa, Khaled Ziadeh, Reem Ashrefa, Adham bader aldeen Mohsen

{"title":"Bilateral choanal atresia in an adult: a rare case report and a literature review","authors":"Yasser Al-Ghabra, Alia Issa, Khaled Ziadeh, Reem Ashrefa, Adham bader aldeen Mohsen","doi":"10.1016/j.xocr.2025.100677","DOIUrl":"10.1016/j.xocr.2025.100677","url":null,"abstract":"<div><h3>Introduction</h3><div>Choanal atresia, a congenital obstruction of the posterior nasal aperture, exhibits divergent clinical trajectories depending on its unilateral or bilateral presentation. While unilateral cases (65–75 %) often evade diagnosis until adulthood due to subtle symptoms, bilateral atresia is a neonatal emergency requiring urgent intervention. Despite its congenital origin, delayed diagnosis persists across age groups due to insufficient clinician recognition of pathognomonic features.</div></div><div><h3>Case presentation</h3><div>A 38-year-old male with lifelong bilateral nasal obstruction and midfacial dysmorphism (rhinomegaly, high-arched palate) was diagnosed as the 17th reported adult with congenital bilateral choanal atresia. Computed tomography (CT) confirmed isolated osseomembranous obstruction (atretic plate thickness: 8 mm) without syndromic associations. The patient underwent successful transnasal endoscopic choanaplasty with stent, achieving sustained patency at 12-month follow-up.</div></div><div><h3>Discussion</h3><div>This case challenges epidemiological norms, as 90 % of diagnoses occur before age 30. Diagnostic precision relied on CT quantification and exclusion of acquired etiologies (e.g., radiotherapy, trauma). The evolution from historical transpalatal approaches (high morbidity) to endoscopic techniques underscores improved outcomes, with stentless protocols now preferred due to reduced restenosis and avoidance of stenting complications. Midfacial adaptations in this patient highlighted chronic compensatory oronasal biomechanics, aligning with studies linking mouth breathing to maxillary constriction.</div></div><div><h3>Conclusion</h3><div>Congenital choanal atresia must remain a differential in adults with refractory nasal obstruction, irrespective of age. Endoscopic stentless repair represents the therapeutic benchmark, balancing efficacy with minimized morbidity.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"36 ","pages":"Article 100677"},"PeriodicalIF":0.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laryngeal schwannoma in a 14-year-old girl 喉神经鞘瘤，14岁女孩

IF 0.2

Otolaryngology Case Reports Pub Date : 2025-09-01 Epub Date: 2025-06-20 DOI: 10.1016/j.xocr.2025.100671

Dominik Tichý , Karol Zeleník , Phillip R. Purnell , Jana Vaculová , Pavel Hurník , Katarína Fedorová , Pavel Komínek

引用次数: 0

Comprehensive approach to pediatric sinonasal rhabdomyosarcoma: Case report and insights from the literature 综合方法治疗小儿鼻窦横纹肌肉瘤：病例报告及文献见解

IF 0.2

Otolaryngology Case Reports Pub Date : 2025-09-01 Epub Date: 2025-05-21 DOI: 10.1016/j.xocr.2025.100666

Siham Oukassem, Soumya El Graini, Chaimae Abourak, Lina Belkouchi, Siham El Haddad, Nazik Allali, Latifa Chat

{"title":"Comprehensive approach to pediatric sinonasal rhabdomyosarcoma: Case report and insights from the literature","authors":"Siham Oukassem, Soumya El Graini, Chaimae Abourak, Lina Belkouchi, Siham El Haddad, Nazik Allali, Latifa Chat","doi":"10.1016/j.xocr.2025.100666","DOIUrl":"10.1016/j.xocr.2025.100666","url":null,"abstract":"<div><h3>Background</h3><div>Rhabdomyosarcoma (RMS) is a rare malignant soft tissue tumor originating from skeletal muscle precursors, most commonly occurring in the pediatric population. Sinonasal rhabdomyosarcoma (PSR) is an uncommon presentation that poses diagnostic and therapeutic challenges due to its rarity, aggressive behavior, and potential for intracranial invasion.</div></div><div><h3>Case presentation</h3><div>We report the case of a 4-year-old girl presenting with persistent frontal headaches, right-eye proptosis, and nasal obstruction. Imaging revealed a large nasosinus mass with significant bone erosion and intracranial extension. Histopathological and immunohistochemical evaluation confirmed the diagnosis of embryonal rhabdomyosarcoma of botryoid type. The patient was classified as high-risk and treated with a multimodal approach, including chemotherapy, radiotherapy, and endoscopic surgery. Follow-up imaging demonstrated a favorable outcome with significant tumor regression and no evidence of recurrence.</div></div><div><h3>Conclusion</h3><div>This case underscores the importance of a multidisciplinary approach in managing pediatric sinonasal rhabdomyosarcoma. Early diagnosis through imaging and biopsy, combined with tailored multimodal therapy, can significantly improve prognosis in high-risk cases. Collaboration between pediatricians, oncologists, and radiologists is essential to determine the optimal treatment strategy for this rare malignancy.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"36 ","pages":"Article 100666"},"PeriodicalIF":0.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Third branchial cleft cyst with pyriform sinus fistula; case report 第三鳃裂囊肿合并梨状窦瘘；病例报告

IF 0.3

Otolaryngology Case Reports Pub Date : 2025-09-01 Epub Date: 2025-08-15 DOI: 10.1016/j.xocr.2025.100685

Abdullah Almutairi , Abdullah Alzamil , Roqaih Aldueb , Ahmed Altuwaijri

引用次数: 0

First reported case of mastoid process osteoma in Syria: Diagnostic and surgical management of a rare temporal bone tumor: A case report 叙利亚首次报道的乳突骨瘤病例：罕见颞骨肿瘤的诊断和手术治疗：1例报告

IF 0.3

Otolaryngology Case Reports Pub Date : 2025-09-01 Epub Date: 2025-07-24 DOI: 10.1016/j.xocr.2025.100678

Bilal Hasan, Jafar Hamdan, Majd Nassr

{"title":"First reported case of mastoid process osteoma in Syria: Diagnostic and surgical management of a rare temporal bone tumor: A case report","authors":"Bilal Hasan, Jafar Hamdan, Majd Nassr","doi":"10.1016/j.xocr.2025.100678","DOIUrl":"10.1016/j.xocr.2025.100678","url":null,"abstract":"<div><h3>Introduction</h3><div>Mastoid osteomas are rare benign osseous tumors, representing only 0.1–1 % of skull osteomas. Most occur in the external auditory canal.</div></div><div><h3>Case presentation</h3><div>A 32-year-old female presented with a 4-year history of a painless, firm right postauricular mass. Clinical examination revealed a fixed, non-tender lump with normal overlying skin and intact hearing. Temporal bone CT demonstrated a well-circumscribed, hyperdense exophytic lesion originating from the right mastoid cortex, without inner ear involvement. A 3D-CT reconstruction precisely delineated the lesion's morphology.</div></div><div><h3>Clinical discussion</h3><div>The patient underwent complete excision via retroauricular approach, with cortical drilling to ensure a margin-free resection. Histopathology confirmed compact osteoma, and no recurrence was observed at 6-month follow-up.</div></div><div><h3>Conclusion</h3><div>This case underscores mastoid osteoma as a diagnostic consideration for slow-growing mastoid masses, despite its rarity. High-resolution temporal bone CT remains pivotal for diagnosis and surgical planning, while complete surgical excision ensures an excellent prognosis.</div></div>","PeriodicalId":37154,"journal":{"name":"Otolaryngology Case Reports","volume":"36 ","pages":"Article 100678"},"PeriodicalIF":0.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144739085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel 3D-printed tracheostomy tube for vertebral erosion in complex pediatric patient 新型3d打印气管造口管用于复杂儿科患者椎体糜烂

IF 0.2

Otolaryngology Case Reports Pub Date : 2025-06-01 Epub Date: 2025-04-04 DOI: 10.1016/j.xocr.2025.100662

Ibrahim Serhat Karakuş , Adam J. Wentworth , Jonathan M. Morris , R Paul Boesch

引用次数: 0

Corrigendum to “Pediatric tracheal mucoepidermoid carcinoma treated with cricotracheal resection: A rare case and review of literature” [Otolaryngology 34 (2025) 100654] “小儿气管黏液表皮样癌经环气管切除治疗一例罕见病例及文献复习”更正[耳鼻咽喉学34 (2025)100654]

IF 0.2

Otolaryngology Case Reports Pub Date : 2025-06-01 Epub Date: 2025-04-08 DOI: 10.1016/j.xocr.2025.100663

Patrick Kiessling , Grace Kim , Kara Meister , Karthik Balakrishnan , Taseer Feroze Din

引用次数: 0