Journal of neonatal-perinatal medicine最新文献

{"title":"Comparison of newborns' characteristics between neonates with proper and improper breastfeeding positions.","authors":"Maryam Zakerihamidi, Gholamali Maamouri, Abbas Boskabadi, Forough Rakhshanizadeh, Zahra Parvini, Asal Ramazani, Fatemeh Bagheri, Hassan Boskabadi","doi":"10.1177/19345798251327382","DOIUrl":"10.1177/19345798251327382","url":null,"abstract":"<p><p>IntroductionProper positioning for successful breastfeeding is important. The current study aimed to compare newborns' characteristics with proper and improper breastfeeding positions.MethodsThe current cross-sectional study was conducted on 591 neonates referred to the Neonatal Clinic, Ward, and Emergency Department of Ghaem Hospital in Mashhad, Iran, within 2019-2023. The subjects were selected through the availability sampling method. Neonates referred for the routine physical examination, jaundiced cases not requiring hospitalization, and newborns with hyperthermia and weight loss were included in the study. Neonates with less than 34 weeks of gestation, jaundiced cases requiring hospitalization, newborns with congenital anomalies, or those with confirmed infectious diseases were excluded from the study. Proper breastfeeding position was considered due to the status of attachment of the neonate to the mother's breast. The data collection tool was a researcher-made checklist, including laboratory data and maternal and neonatal characteristics. The data were analyzed using the t-test and chi-square test.ResultsAmong the 591 neonates, 466 (78.8%) and 125 (21.2%) subjects were nursed with proper and improper positioning, respectively. There were significant differences between the two groups in terms of admission weight (<i>p</i> = .000), daily weight loss (<i>p</i> = .000), daily weight loss percentage (<i>p</i> = .000), first breastfeeding time after delivery (<i>p</i> = .000), breastfeeding frequency (<i>p</i> = .000), breastfeeding duration (<i>p</i> = .002), urination frequency (<i>p</i> = .000), defecation frequency (<i>p</i> = .000), and serum levels of sodium (<i>p</i> = .000), urea (<i>p</i> = .000), creatinine (<i>p</i> = .000), hematocrit (<i>p</i> = .002), platelet count (<i>p</i> = .001), and blood glucose (<i>p</i> = .010). Moreover, lethargy, irritability, seizure, mucosal dryness, inverted fontanelle, hyperthermia, unsoftened breast after breastfeeding, nipple fissure, and pregnancy problems were higher in the group nursed with improper positioning than the other group.ConclusionIn our study, breast problems, feeding problems, hypernatremia, hyperuremia, and weight loss were more common in infants of mothers with improper positioning of breastfeeding. Therefore, it is recommended to provide mothers with appropriate training and strategies for proper breastfeeding position.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"218-225"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of neonatal near miss among neonates admitted at Bahir Dar public hospitals, North West Ethiopia: A case-control study.","authors":"Daniel Mekete Alemu, Eleni Admasu, Mekonnen Melkie, Asnake Gashaw Belayneh","doi":"10.1177/19345798251324513","DOIUrl":"https://doi.org/10.1177/19345798251324513","url":null,"abstract":"<p><p>BackgroundNeonatal near miss is a significant public health issue in Ethiopia. Previous studies have often overlooked health system-related and behavioral factors of neonatal near miss. This study aimed to identify determinants of neonatal near misses in Bahir Dar public hospitals to fill those gaps in the aforementioned studies.MethodsAn unmatched case-control study was conducted in Bahir Dar public hospitals from October to December 2022, involving 443 neonates (147 cases, 296 controls). Cases were recruited consecutively, while controls were selected using systematic sampling. Data were collected using a pre-tested structured interviewer-administered questionnaire at discharge and from patients' cards using Epicollect5. Data were analyzed with SPSS version 26 for bivariable and multivariable binary logistic regression at a 95% confidence interval (CI). The Hosmer and Lemeshow test checked the model fit, with <i>p</i>-value <0.05 considered significant.ResultsDeterminants of neonatal near misses included not receiving exclusive breastfeeding within an hour of delivery [AOR = 3.13, 95% CI: 1.25, 7.83], a history of pregnancy-induced hypertension [AOR = 5.55, 95% CI: 2.34, 12.85], fewer than four antenatal care visits [AOR = 8.38, 95% CI: 3.62, 19.44], and travel time over an hour to reach health facilities [AOR = 6.55, 95% CI: 2.56, 16.78].Conclusion and recommendationDelayed initiation of exclusive breastfeeding, pregnancy-induced hypertension, travel time to health facilities, and the number of antenatal care visits were key determinants of neonatal near miss. Enhancing maternal health services, such as exclusive breastfeeding practices, increasing antenatal visits, improving ambulance accessibility, and prioritizing mothers with pregnancy-induced hypertension, is essential.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":"18 3","pages":"235-245"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malposition of a nasogastric tube into the middle ear of a premature one week old infant.","authors":"Abeer Alali, Sharon Cushing, Adrian James, Krista Marcotte, Noah Ditkofsky","doi":"10.1177/19345798251327369","DOIUrl":"10.1177/19345798251327369","url":null,"abstract":"<p><p>A significant number of pediatric patients require a nasogastric tube (NGT) during their hospital stay for indications including nutrition support, medication delivery and decompression of the gastrointestinal tract. As such NGT placement is commonly performed; however, misplacement can occur into other anatomic sites within proximity.Primary DiagnosisWe report a first in the literature case of NGT misplacement into the middle ear via the eustachian tube in a one-week-old premature infant that required an NGT for feeding support.Clinical FindingsThere was no reported resistance or concerns during NGT insertion; however, blood was noted in the syringe during aspiration performed to confirm tube position. A plain film radiograph and thereafter high-resolution computed tomography (HRCT) imagining confirmed the malposition of the tube within the middle ear.Interventions and OutcomesAfter transfer to a tertiary center, the NGT was removed without event in the neonatal intensive care unit (NICU) under direct vision with a flexible nasal endoscopy and successful replacement occurred thereafter. No injury to the middle ear structures or hearing occurred.Practice RecommendationsWhile not a common site of misplacement, nasogastric tubes can be misdirected via the eustachian tube into the middle ear. Imaging modalities such as plain film radiographs and computed tomography can be helpful when misplacement is suspected based on bedside assessment. Protocols for routine replacement of functional nasogastric tubes after specific time periods in an effort to prevent nasal alar or nasal cavity complications from pressure should consider the risk of misplacement and consequences thereof.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":"18 3","pages":"282-284"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of stress-induced hemolysis in neonatal intravenous catheters: Theoretical and experimental analysis of shear stress, exposure time, and index of hemolysis.","authors":"Gordon Y Chang, Cynthia A Cox, Ellen A Kane, Giovanna Palermo Tye, Paul Fawcett, Thomas H Shaffer","doi":"10.1177/19345798251326071","DOIUrl":"10.1177/19345798251326071","url":null,"abstract":"<p><p>BackgroundSeveral studies report hemolysis when packed red blood cells (PRBCs) are transfused through small-inner-diameter (ID) catheters using presence of biomarkers but do not address cause and amount of hemolysis. This study aims to determine the cause and index of hemolysis percent (IH%) when PRBCs are infused through small-ID catheters.MethodsThe IH% was calculated using Giersiepen's empirical power law, which describes a relationship between hemolysis and magnitude of shear stress and exposure time. Six- and 27-day-old PRBCs were infused through five catheters with IDs of 0.20 mm to 0.70 mm at infusion rates of 3 mL and 10 mL/hour. Shear stress and exposure time were calculated. Data were analyzed as a function of catheter ID, infusion rates, and blood age.ResultsThe study demonstrated that shear stress was supraphysiologic during laminar flow in catheters with IDs of 0.20 mm and 0.28 mm. These catheters' IH% were ∼117 times higher at 3 mL/hour and ∼75 times higher at 10 mL/hour than catheters with larger IDs of 0.48 mm, 0.51 mm, and 0.70 mm. For blood age, in catheters with IDs of 0.20 mm and 0.28 mm, IH% was ∼155 times higher at 6 days and ∼76 times higher at 27 days than in catheters with IDs of 0.48 mm, 0.51 mm, and 0.70 mm.ConclusionsThis study demonstrated that when RBCs are subjected to supraphysiologic shear stress in catheters with IDs of ≤0.28 mm, index of hemolysis is greater than in catheters with IDs ≥0.48 mm.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"255-269"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and limitations of the prenatal sonographic assessment of choanal flow and neonatal implications.","authors":"Assaad Kesrouani, Nadine Cheaib, Wael Abdalla, Alain Daher, Fadi Sleilaty","doi":"10.1177/19345798251336732","DOIUrl":"https://doi.org/10.1177/19345798251336732","url":null,"abstract":"<p><p>ObjectiveTo evaluate the factors associated with the prenatal detection of choanal flow (CF) in a normal population.MethodsFifty pregnant women underwent CF evaluation using B-Mode and color Doppler. Screening for CF began at 22 weeks, standardized according to two section planes: sagittal and transverse. CF was considered positive when flow was seen, and negative if no flow was detected after 1 minute. The screening was repeated monthly until flow was observed. We assessed maternal BMI, fetal gender, gestational age at the first detection of flow, placental site, visibility noted by the sonographer, nasal asymmetry, and possible nostril dilatation.ResultsChoanal flow was established in all patients except two cases where the fetal face was consistently downwards (48/50). The gestational age at first detection of choanal flow was 28 weeks ± 3.5 weeks. Flow was unilateral in 56.3% of cases and bilateral in 43.8% of cases. Visibility assessed by the operator was rated as good in 72% of cases, average in 20%, and poor in 8%. The only factor significantly associated with the gestational age at first detection of choanal flow was visibility (<i>p</i> = 0.006).ConclusionThe average gestational age for the detection of choanal flow is 28 weeks. Relying solely on second-trimester morphological ultrasound may result in missed detections.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"19345798251336732"},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocardial calcifications in a neonate with surgically corrected truncus arteriosus: Case report.","authors":"Celia Permuy, María Sánchez-Holgado, Paloma López-Ortego, Monserrat Bret, Carlos Labrandero, Mercedes Sampedro, Juvenal Rey, Esther Mazarío, Adelina Pellicer","doi":"10.1177/19345798251337296","DOIUrl":"https://doi.org/10.1177/19345798251337296","url":null,"abstract":"<p><p>BackgroundMyocardial calcifications in neonates with truncus arteriosus are rare and poorly understood. These calcifications, resulting from dystrophic processes in injured tissue, may have significant clinical implications. This case highlights a neonate with truncus arteriosus and interrupted aortic arch who developed extensive myocardial calcifications following surgical correction and extracorporeal membrane oxygenation (ECMO).MethodsA neonate with truncus arteriosus underwent surgical repair at 11 days of life, requiring ECMO support. Clinical data, imaging findings, and therapeutic interventions were analyzed to explore the pathophysiology and clinical implications of myocardial calcifications.ResultsThe patient developed recurrent ischemic episodes, significant left ventricular dysfunction, and severe vascular abnormalities. Echocardiography and computed tomography revealed extensive myocardial and extracardiac calcifications. Despite maintaining normal calcium levels, myocardial calcifications were accompanied by progressive heart failure. Surgical attempts to address associated coronary and valvular complications failed to improve outcomes, leading to intractable heart failure and death at 4.5 months of age.ConclusionsThis case underscores the potential role of ischemia-reperfusion injuries, ECMO, and neonatal surgical interventions in the pathogenesis of myocardial calcifications in complex congenital heart disease. These findings highlight the need for further research into preventative and therapeutic strategies for this severe and rare complication.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"19345798251337296"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal malignant pertussis and exchange transfusion: A case report.","authors":"Abdessamad Lalaoui, Ghizlane Kassal, Chaima Haidar, Khalid Abi El Aala, Fatiha Bennaoui, Nadia El Idrissi Slitine, Asma Hanchi, Nabila Soraa, Fadl Mrabih Rabou Maoulainine","doi":"10.1177/19345798251330800","DOIUrl":"https://doi.org/10.1177/19345798251330800","url":null,"abstract":"<p><p>Whooping cough (pertussis) is a bacterial infection caused by Bordetella pertussis. It poses a significant risk, especially in neonates. This contagious respiratory infection is transmitted via the aerosol route from human reservoirs. The severe form can lead to mortality in approximately 70% of cases. The aim of our study is to report the severity of malignant whooping cough in neonates and the potential contribution of exchange transfusion to improving prognosis. In this case, a 26-day-old infant presented with malignant whooping cough, confirmed by PCR testing. Initial clinical findings included tachycardia, fever, dyspnea, and right apical lesion with pulmonary arterial hypertension. Despite initial treatment with josamycin and supportive measures, the patient's condition deteriorated, requiring an exchange transfusion, which led to clinical improvement. The patient was successfully discharged after a 12-day hospitalization. Exchange transfusion should be considered for malignant whooping cough with leukocytosis and acute respiratory failure, but enhancing vaccination coverage remains the most effective prevention strategy.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"19345798251330800"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal inpatient stays longer than one year: Who was admitted, what happened, and how much did it cost?","authors":"Nihaal Shah, Angel Sunny, Fredrick Dapaah-Siakwan","doi":"10.1177/19345798251315153","DOIUrl":"10.1177/19345798251315153","url":null,"abstract":"<p><p>BackgroundAnecdotal evidence suggests that some preterm infants remain hospitalized for more than a year, but little is known about this population. We aimed to describe the characteristics, the hospital course, and the hospital costs for preterm hospitalizations with length of stay (LOS) ≥365 days.MethodsThis was a retrospective, descriptive cohort study of the 2016 and 2019 Kids Inpatient Database. ICD-10 codes were used to identify preterm infants, their comorbidities, and surgical interventions. The study population was dichotomized into LOS ≤364 days (PT364) and LOS ≥365 days (PT365) and compared using Chi-square or Mann-Whitney U test as appropriate. The exposure was PT365, and the outcomes were the characteristics, comorbidities, discharge disposition, and inflation-adjusted hospital costs.ResultsAmong 688,995 preterm infants, 111 had LOS ≥365 days (0.016%). Compared to PT364, PT365 were more likely to be males (74.6% vs 53.2%), of gestational age ≤27 weeks (71.5% vs 4.7%), and <1000 gm birthweight (64.2% vs 4.0%). PT365 were more likely to have a higher prevalence of comorbidities in each organ system, surgical and procedural interventions, and neonatal chronic complex conditions (872% vs 13.3%). PT365 were less likely to be discharged home (45.7% vs 93.4%) and more likely to be discharged to home healthcare (28.0% vs 5.7%) or to a skilled nursing facility (16.0% vs 0.8). The median hospital cost per surviving PT365 was $1,616,336.ConclusionPT365 was rare but was associated with complex chronic conditions, increased morbidity and surgical burden, and high inflation-adjusted hospital costs.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"173-178"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differences in survival rates among extreme low birth weight infants: Insight from a 16-year, single-centre study.","authors":"Mansour Al Qurashi","doi":"10.1177/19345798241310150","DOIUrl":"https://doi.org/10.1177/19345798241310150","url":null,"abstract":"<p><p>BackgroundPreterm infants with a birth weight of less than 1000 grams (g), extreme low birth weight (ELBW) account for approximately 0.6% of all live births. Despite their small proportion, they contribute significantly to neonatal deaths, short-term morbidities, and long-term sequalae among survivors. This study aims to evaluate the survival trends of ELBW infants over the study period and the impact of gender on survival odds.MethodsThis retrospective cohort study involved ELBW infants admitted to our neonatal intensive care unit over 16 years (2008-2023). We examined their survival trends in context with their gender to analyze impact on survival odds.ResultsOut of 336 infants who met the inclusion criteria, 175 were males (52.1%) and 161 (47.9%) were females. The mean birth weight for males was 780 g (SD = 134 g), and 770 g (SD = 132) for females, while the mean gestational age (GA) was 26.2 weeks (SD = 2.14 week) for males and 26.6 weeks (SD = 2.18 week) for females. Female ELBW infants had a higher survival rate of 78.9% compared to 68.6% for males, with an odds ratio (OR) of 1.712 (<i>p</i> value = 0.017). The survival advantage for females was more evident among birth weight of less than (<) 750 g (62% vs 44%) with an OR of 2.06 (<i>p</i> value = 0.023).ConclusionThis study demonstrated that female ELBW infants have a higher survival rate than males, particularly with birth weight under 750 g.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":"18 2","pages":"137-141"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ping-pong skull fracture in a neonate managed successfully with vacuum-assisted technique.","authors":"Omer Akbar, Khaled Abushafi, Heba AlShaikh, Abdulaziz Al-Khotani, Mansour Al Qurashi","doi":"10.1177/19345798241309879","DOIUrl":"10.1177/19345798241309879","url":null,"abstract":"<p><p>Ping-pong fractures (PPFs) are rare types of depressed skull fractures that occur in neonates due to mechanical traumatic factors. Such conditions result in inward bowing of the skull bones, but its continuity remains intact. In this paper, we report a case of PPF in a female newborn infant associated with instrumental delivery, which was managed non-surgically with a vacuum extraction method. Because such a condition is uncommon and can be effectively managed with a relatively easy non-invasive method, this case is clinically interesting.</p>","PeriodicalId":16537,"journal":{"name":"Journal of neonatal-perinatal medicine","volume":" ","pages":"167-172"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}