{"title":"INDIVIDUALIZED MEDICINE: REVOLUTIONIZING HEALTHCARE WITH TAILORED THERAPIES","authors":"Siddhesh G Waghmare, Ameetul Noor Zeba Khannam","doi":"10.36713/epra17655","DOIUrl":"https://doi.org/10.36713/epra17655","url":null,"abstract":"Individualized medicine is changing the way as we approach the healthcare by customizing the medical treatments to fit each person's unique genetic makeup, environmental influences, and to lifestyle choices. This concept focuses on the idea of that every patient is unique, but with genetic differences that influence their health and how they respond to the treatments. By using advanced technologies such as genomics (the study of genes and their functions), proteomics (the study of proteins and their functions), and the detailed patient data, precision medicine allows doctors to identify an specific genetic markers and molecular causes of diseases. With this information, the healthcare providers can create personalized treatment plans that target the exact causes of an illnesses, making the treatments more effective and reducing the side effects. We already have seen the benefits of precision medicine in the cancer treatment, where specific therapies designed to target specific genetic mutations have significantly improved patient outcomes. However, the potential of precision medicine extends far beyond the oncology. It could revolutionize the treatment of heart diseases, neurological disorders, rare genetic conditions, and many other health issues. Despite its promise, the precision medicine faces challenges like ensuring data security, addressing the ethical concerns, and providing equal access to such advanced treatments. Nevertheless, the future of the precision medicine looks bright. It aims to create a healthcare system that is more focused on the individual patients, providing treatments tailored to each person's unique biology and requirement. This approach is expected to lead to a more better health outcomes with a higher quality of life for many people.","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":"5 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141665370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexis Mae I. Aquino, Jhoan G. Simangan, Eduard S. Ualat, Martina R. Peñalber
{"title":"RICE EEL (Monopterus albus) FISHBALL FORTIFIED WITH CASSAVA - BASED SAGIP NUTRI- POWDER","authors":"Alexis Mae I. Aquino, Jhoan G. Simangan, Eduard S. Ualat, Martina R. Peñalber","doi":"10.36713/epra17661","DOIUrl":"https://doi.org/10.36713/epra17661","url":null,"abstract":"This study was conducted to determine the benefits of Rice Eel (Monopterus albus) Fishball Fortified with Cassava-Based SAGIP Nutri-Powder in promoting nutritious food to improve individual’s health and well-being. One purpose of the study was to address and mitigate the malnutrition covered by the BIDANI among 14 barangays in the municipality of Echague, Isabela. The study involved four treatments: Treatment 1 (Commercial Fishball), Treatment 2 (50 grams CBSNP, 200 grams Rice eel flesh), Treatment 3 (100 grams CBSNP, 300 grams Rice eel flesh), and Treatment 4 (150 grams CBSNP, 500 grams Rice eel flesh, 250 grams All-purpose flour). A 9-point Hedonic Scale was used for sensory evaluation, in terms of appearance/color, aroma/odor, flavor/taste, and general acceptability. Sixty (60) respondents, categorized as students, tricycle drivers/farmers, and professionals aged 18-50 years old, served as panelist. Treatment 3 received the highest mean score across all treatments, with the quantitative description of “Like Very Much.” Statistical analysis showed no significant differences among the treatments in terms of appearance/color, aroma/odor, flavor/taste, and general acceptability. However, Treatment 3 consistently received the highest ratings. The Return on Investment (ROI) analysis revealed that Treatment 2 was the most profitable for a business venture. Furthermore, the study underscores the importance of developing innovative, nutritious food products to improve public health. The development of such products can play a crucial role in improving the dietary habits and overall health of the population. \u0000KEYWORDS: BIDANI, CBSNP, Fishball,Fortified, Rice Eel","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":"60 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141663276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EVALUATION OF THE MECHANICAL PROPERTIES OF STYRENE BUTADIENE RUBBER(SBR)/BANANA FIBRE(BF) COMPOSITES","authors":"Toms Philip, Dr.N.H Jayadas","doi":"10.36713/epra17640","DOIUrl":"https://doi.org/10.36713/epra17640","url":null,"abstract":"Tensile strength, rip strength, abrasion loss, hardness, and thermal conductivity are the main characteristics of Styrene-Butadiene Rubber (SBR) composites that are examined in this work as a function of increasing banana fibre loading. Because banana fibres are reinforcing, adding them to the SBR matrix initially increases tensile and tear strength. However, there is an ideal concentration at which fibre aggregation and poor interfacial bonding cause these qualities to drop. Abrasion loss increases with higher loadings because of insufficient fibre dispersion, but it decreases with moderate fibre concentration, indicating enhanced wear resistance. Fibre addition improves the composites' hardness up to a certain point, beyond which adding too many fibres causes inconsistent results and lower hardness. It is discovered that as fibre counts increase, thermal conductivity decreases.\u0000KEYWORDS—SBR composites, tensile strength, thermal conducutivty.","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":"41 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141664959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A STUDY ON OCCUPATIONAL STRESS AMONG WOMEN WITH SPECIAL REFERENCE TO BANKING SECTOR","authors":"Ms. Teresa Stephen, Dr.Asha E Thomas","doi":"10.36713/epra17596","DOIUrl":"https://doi.org/10.36713/epra17596","url":null,"abstract":"Occupational stress stems from unexpected responsibilities and pressures that do not align with a person's knowledge, skills, or expectations, inhibiting one's ability to cope. It can increase when workers do not feel supported by supervisors or colleagues, or feel as if they have little control over work processes. The need for the study is to ascertain specific problems of employees related to job stress and to find out the level of stress. The present study will help to develop more appropriate strategies to minimize the job stress of employees and these could be incorporated into a well-designed set of human resources policies and also helps as one of the sources for the secondary data for future research also. This study is helpful in assessing the extent of stress experienced by women employees in Banking sector. The population selected for this study are employees of banks mainly women. The sampling population of this study includes 30 women employees from banking sector. Both primary and secondary data were used for the study.\u0000KEY TERMS: Occupational Stress, Banking Sector","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141673301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PERFORMANCE OF UCB AND CUSTOMERS SATISFACTION TOWARDS TUCBL","authors":"Dr. S.A. Mohamed Ali, Ms. Najma B","doi":"10.36713/epra17517","DOIUrl":"https://doi.org/10.36713/epra17517","url":null,"abstract":"UCB (Urban Cooperative Banks) as part of cooperative banking are deemed as the integral part of Indian economic growth. UCB channelise the deposits and saving accumulated into productive loans extended to small and medium scale business ventures. UCBs offers prime banking service to the urban poor i.e., both banking and financial assistance. This research article assessed performance of UCBs and various categories of customers satisfaction towards UCBs is assessed. The study considered 410 TUCBLs (Tirchur Urban Cooperative Limited) customers as sample. The article findings confirmed that 81.80 per cent are pleased with the TUBL staff behaviour towards their customers, they also appreciated the account opening procedure followed by TUBCL (80.40 per cent) and account closing procedures (78.20 per cent). The article also found that there exists association between nature of deposits owned, loan borrowed and services availed by TUCBL customers and their satisfaction towards overall services cum performance of TUCBL. The article concluded with the note that definitely, with able governance and controlling mechanism adoption the UCBs can perform well and support of the apex financial regulation agencies and RBI. In addition, customers play a greater role in sustainability of the UCBs, with their patronage UCBs functioning in Kerala can achieve new highest and new mile-stones. \u0000KEY WORDS: Cooperative Bank, Urban Cooperative Bank, Customers Satisfaction.","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":"2 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141684871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EDUCATIONAL PHILOSOPHY OF SRI AUROBINDO: A TRANSCENDENT VISION FOR HOLISTIC LEARNING","authors":"Khokan Das, Suvendu Ray","doi":"10.36713/epra17381","DOIUrl":"https://doi.org/10.36713/epra17381","url":null,"abstract":"Sri Aurobindo was an idealistic person based on Vedantic and Upanishad, and his educational philosophy aimed to develop the skills of Indians for self-creation and eternal spirit. This study aimed to create a life sketch of Sri Aurobindo, analyze his philosophical perspectives, and explore the relevance of his philosophy for holistic learning. The investigator employed a qualitative research methodology to investigate secondary sources such as books, online journals, and documents. The study explored Sri Aurobindo's philosophy, which advocates for holistic learning that encompasses physical, emotional, mental, and spiritual aspects. The philosophy is rooted in Sri Aurobindo's evolutionary worldview, aiming to nurture individuals who are intellectually competent, morally upright, and spiritually awakened. It also emphasizes personalized learning, respecting individuality and integrating spiritual values into the learning process. The study on Sri Aurobindo's educational philosophy suggests a holistic approach, emphasizing mindfulness practices and spiritual values in teaching methods, rather than academic achievement. Sri Aurobindo's educational philosophy transcends cultural, geographical, and temporal boundaries, promoting holistic learning and empowering individuals for a more enlightened future.\u0000KEY WORDS: Sri Aurobindo, Educational Philosophy, Holistic Learning, Integral Education","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":"47 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141343675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ANALYSIS OF FACTORS MOTIVATING THE BUILDING AND OTHER CONSTRUCTION WORKERS FOR REGISTRATION UNDER THE BUILDING AND OTHER CONSTRUCTION WORKERS WELFARE BOARD","authors":"Sushree Sanghamitra, Dr. Kailash Chandra Mishra","doi":"10.36713/epra17282","DOIUrl":"https://doi.org/10.36713/epra17282","url":null,"abstract":"This study aims to observe and know the Labour welfare measures which play a significant role that influencing the level of job satisfaction of employees and help the employers in indifferent ways. So certain amount of investment for the success and the progress of the organizations or the construction sites and somehow for the society. The universe of the study includes three hundred building construction workers from different construction sites within the Mayurbhanj district of Odisha. After collecting the data, they were coded and analysed by using SPSS. Binary Logistic Regression Analysis was used to show the relationship between the registration of construction workers and different labour welfare measures of OB&OCWWB. Results indicated that the registration of building construction workers depends upon the increased monetary benefits that they receive from the welfare board. This registration of the workers under the board does not depend upon their age, level of education, type of work, duration of working hours, tenure of job, and other basic amenities they receive from the board. The result of the binary logistic regression shows that different welfare measures significantly affect the registration of building construction workers under the welfare board. \u0000KEY WORDS: Welfare Measures, Binary Logistic Regression, Construction Worker, Welfare Board, Construction Sites.","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":"30 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141357502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IMPLEMENTATION OF ENERGY EFFICIENT SECURITY MECHANISMS FOR WIRELESS SENSOR NETWORKS","authors":"Sirasani Srinivasa Rao, Gajula Madhavi, G.Ravi Kumar","doi":"10.36713/epra17302","DOIUrl":"https://doi.org/10.36713/epra17302","url":null,"abstract":"Designing energy-efficient security mechanisms is critical for WSNs due to their limited power resources. Techniques like low-power cryptography, duty cycling, and energy-aware security protocols can help in achieving security without significantly impacting the energy consumption of sensor nodes. In this paper, we propose an energy aware geographical multipath routing scheme for WSNs. The distance to the destination location, remaining battery capacity, and queue size of candidate sensor nodes in the local communication range are taken into consideration for next hop relay node selection, and Analytical Hierarchy Process (AHP) and Geographical Routing Algorithm (GRA) are applied for decision making. Simulation results show that these schemes can extend the network lifetime longer than the original geographical routing scheme which only considers distance to the destination location. \u0000KEYWORDS: WSN, linear discriminate packet flow analysis system, optimized rout path switch, Analytical Hierarchy Process (AHP) and Geographical Routing Algorithms(GRA).","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":"79 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141359731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RISK ASSESSMENT IN FINANCIAL DECISION MAKING ANALYSIS ON FISHERMAN PERSPECTIVE IN COASTAL REGION: A CASE STUDY","authors":"Mr. Swarn G Kanchan, Dr. C. K. Hebbar","doi":"10.36713/epra17298","DOIUrl":"https://doi.org/10.36713/epra17298","url":null,"abstract":"Assessing financial decision-making from a fisherman's perspective in coastal regions involves considering a range of risks. Market volatility, driven by fluctuations in fish prices and changing consumer demands, poses immediate challenges. Environmental factors, such as climate change and natural disasters, can disrupt fishing conditions, impacting yields. Regulatory uncertainties, including shifts in fishing quotas and environmental compliance standards, add complexities. Technological advancements may necessitate investments, while limited access to credit and interest rate fluctuations present financial risks. Study is done with secondary data such as case studies, literature reviews, books, blogs and internet sources. Findings show that it is reasonable to expect that conflicts in fisheries management will increase with time as human population grows and seafood demand increases.\u0000KEYWORDS: Risk Assessment, Financial Decision Making, Fisherman, Population, Coastal Region.","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":"50 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141358378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AN OVERVIEW ON CANCER CHRONOTHERAPY","authors":"Rachana Botla, Syeda Nishat Fathima","doi":"10.36713/epra17244","DOIUrl":"https://doi.org/10.36713/epra17244","url":null,"abstract":"The circadian clock is a complex biological circuitry that controls the daily rhythm of functions such as sleep, body temperature, and digestion. The master “clock” is an area in the brain that senses environmental cues (such as light) and communicates information to secondary clocks in other organs. The breaking of circadian tolerance or disbalance in the circadian clock results in the outbreak of several diseases. The prime factors that play in a disbalance circadian clock are artificial light during day or night, unbalanced diet, work-life balance, and unbalanced lifestyle. Defects or disruption in normal circadian functioning and altered levels of clock gene expressions can increase the risk of prostate cancers, breast cancers, ovarian cancers, colorectal cancers, endometrial cancers, non-Hodgkin’s lymphoma, pancreatic cancers, osteosarcomas, head and neck squamous cell carcinomas, acute myeloid leukemia, and hepatocellular carcinomas. Chronotherapy for cancer involves optimal timing of drug delivery based on individual circadian times, which can improve treatment tolerability and efficacy of anti-cancer medications.\u0000KEYWORDS: Chronotherapy; Cancer; Biological clock","PeriodicalId":114964,"journal":{"name":"EPRA International Journal of Research & Development (IJRD)","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141367838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}