综合性期刊最新文献

{"title":"Identifying the Respiratory Sound Based on Single-Channel Separation and Hyperdimensional Computing","authors":"Jie Zheng;Yixuan Wang;Jinglong Niu;Yan Shi;Fei Xie","doi":"10.1109/JSEN.2025.3557909","DOIUrl":"https://doi.org/10.1109/JSEN.2025.3557909","url":null,"abstract":"In intensive care units (ICUs), efficient respiratory management, particularly sputum suction in weakened patients, is critical. Traditional stethoscope-based methods for respiratory sound analysis in tracheal sputum assessment are time-consuming and often struggle to differentiate between cardiac and respiratory sounds, affecting sputum detection accuracy. To address these issues, we propose identifying respiratory sound based on single-channel separation and hyperdimensional computing (IRS-SSHC). Specifically, the proposed method first employs an encoder-decoder framework to effectively separate heart and respiratory sounds in the time domain. Then, it segments respiratory sounds using short-duration energy, where each segment is represented by a 1024-D vector space. Next, it utilizes light gradient boosting machine (LightGBM) based on the vector space for classification. Experimental results show that the classification ACC of IRS-SSHC is 97.9%, which outperforms existing methods.","PeriodicalId":447,"journal":{"name":"IEEE Sensors Journal","volume":"25 13","pages":"24626-24633"},"PeriodicalIF":4.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144550219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technical Advisory Group on the Structural Integrity review of the fatigue crack growth approach to transient cycles and other parameters used.","authors":"Anthony Horn, Peter James, Peter Budden, Keith Wright, Mike Nielsen","doi":"10.1098/rsta.2024.0174","DOIUrl":"https://doi.org/10.1098/rsta.2024.0174","url":null,"abstract":"<p><p>TAGSI is the UK Technical Advisory Group for the Structural Integrity of high-integrity components (HICs) and has a role in reviewing specific technical questions from its sponsors through peer review utilizing independent experts. EDF-Nuclear Services (NS) asked TAGSI to review some proposed optimizations for calculating fatigue crack growth (FCG) and to provide some further insight into the basis of certain relevant parameters. The areas covered were as follows: numerical approaches to FCG evaluation using elastic-plastic cracked-body finite-element (FE) methods; the function of <i>R</i>-ratio term <i>f</i>(<i>R</i>) in RSE-M for Δ<i>K</i>_eff; and a new proposal for ordering and pairing transients aligned with plant operating conditions (POCs), referred to as the POC approach. This paper provides an overview of the review and associated discussions to address these questions. The main findings were as follows: TAGSI considers that the use of the Δ<i>J</i> parameter for estimating FCG in the elastic-plastic regime is consistent with UK guidance, though some caveats and points for consideration were noted. Although the basis for the <i>f</i>(<i>R</i>) term in RSE-M is not well documented, some suggestions were made for how this may be better understood and developed. The POC method adopts a different approach to traditional methods for both the ordering and pairing of transients. TAGSI considers that the chronological POC approach (when including a modification, POC-mod, to combine start-up and shutdown transients) is an appropriate method for the ordering of transients for assessment. Some areas of non-conservatism were noted, to be assessed on a case-by-case basis.This article is part of the theme issue 'Future challenges for structural integrity of high-integrity components'.</p>","PeriodicalId":19879,"journal":{"name":"Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences","volume":"383 2300","pages":"20240174"},"PeriodicalIF":4.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144554099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A smart energy management system for surface unmanned vehicles for border surveillance missions.","authors":"João F P Fernandes, Mário Assunção, Daniel Serrano, Pedro Afonso, Pedro Pinheiro, Hugo Marques, José Neves, Pedro Teodoro, Ricardo Póvoa, Rosa Marat-Mendes, P J Costa Branco","doi":"10.1038/s41598-025-08579-x","DOIUrl":"https://doi.org/10.1038/s41598-025-08579-x","url":null,"abstract":"<p><p>This work proposes a methodology to extend the range of marine unmanned surface vehicles (USV) for border surveillance missions. The typical small scale of USVs and their lack of in-board pilots make USVs an important tool for remote applications, such as border surveillance missions and for dangerous areas operations. However, also due to their small scale, their mission range is typically limited. In this paper, it is proposed a combination of a smart energy management system (SEMS) with electric propulsion and photovoltaic panels to find the optimal path and speed capable of extending the mission range. The developed SEMS is capable of planning a mission profile based on the predicted environmental conditions. To achieve this, one presents a new A-star algorithm with probabilistic behaviour to avoid local minimums and find alternative paths that would reduce the energy consumption in later hours of the mission. The developed system was included in a USV prototype and tested under real environmental conditions at the interface between the Tejo River and the Atlantic Sea, in Lisbon, Portugal. Experimental results showed that the inclusion of photovoltaic panels and the SEMS allowed for planning the mission including the time-variable environmental conditions, leading to an extension of up to 50% of the mission range.</p>","PeriodicalId":21811,"journal":{"name":"Scientific Reports","volume":"15 1","pages":"23684"},"PeriodicalIF":3.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144554438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Correction: Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors","authors":"Wei Xia, Jing Xie, Zhiqing Cai, Xuhua Liu, Jing Wen, Zhong-Kai Cui, Run Zhao, Xiaomei Zhou, Jiahui Chen, Xinru Mao, Zhengtao Gu, Zhimin Zou, Zhipeng Zou, Yue Zhang, Ming Zhao, Maegele Mac, Qiancheng Song, Xiaochun Bai","doi":"10.1038/s41467-025-61622-3","DOIUrl":"https://doi.org/10.1038/s41467-025-61622-3","url":null,"abstract":"<p>Correction to: <i>Nature Communications</i> https://doi.org/10.1038/s41467-021-26302-y, published online 15 October 2021</p>","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"20 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phylogenetically informed predictions outperform predictive equations in real and simulated data","authors":"Jacob D. Gardner, Joanna Baker, Chris Venditti, Chris L. Organ","doi":"10.1038/s41467-025-61036-1","DOIUrl":"https://doi.org/10.1038/s41467-025-61036-1","url":null,"abstract":"<p>Inferring unknown trait values is ubiquitous across biological sciences—whether for reconstructing the past, imputing missing values for further analysis, or understanding evolution. Models explicitly incorporating shared ancestry amongst species with both known and unknown values (phylogenetically informed prediction) provide accurate reconstructions. However, 25 years after the introduction of such models, it remains common practice to simply use predictive equations derived from phylogenetic generalised least squares or ordinary least squares regression models to calculate unknown values. Here, we use a comprehensive set of simulations to demonstrate two- to three-fold improvement in the performance of phylogenetically informed predictions compared to both ordinary least squares and phylogenetic generalised least squares predictive equations. We found that phylogenetically informed prediction using the relationship between two weakly correlated (r = 0.25) traits was roughly equivalent to (or even better than) predictive equations for strongly correlated traits (r = 0.75). A critique and comparison of four published predictive analyses showcase real-world examples of phylogenetically informed prediction. We also highlight the importance of prediction intervals, which increase with increasing phylogenetic branch length. Finally, we offer guidelines to making phylogenetically informed predictions across diverse fields such as ecology, epidemiology, evolution, oncology, and palaeontology.</p>","PeriodicalId":19066,"journal":{"name":"Nature Communications","volume":"5 1","pages":""},"PeriodicalIF":16.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression","authors":"Daniëlle Bianchi,&nbsp;Razvan Borza,&nbsp;Erica De Zan,&nbsp;Guizela Huelsz-Prince,&nbsp;Sebastian Gregoricchio,&nbsp;Marleen Dekker,&nbsp;Alex Fish,&nbsp;Abdelghani Mazouzi,&nbsp;Lona J. Kroese,&nbsp;Simon Linder,&nbsp;Miguel Hernandez-Quiles,&nbsp;Michiel Vermeulen,&nbsp;Patrick H. N. Celie,&nbsp;Paul Krimpenfort,&nbsp;Ji-Ying Song,&nbsp;Wilbert Zwart,&nbsp;Lodewyk Wessels,&nbsp;Sebastian M. B. Nijman,&nbsp;Anastassis Perrakis,&nbsp;Thijn R. Brummelkamp","doi":"10.1126/science.adv2861","DOIUrl":"10.1126/science.adv2861","url":null,"abstract":"<div >Zinc finger proteins (ZNFs) are the largest family of transcription factors, yet how they activate gene expression remains unclear. In this study, we identified Zincore, a protein complex consisting of QRICH1 and SEPHS1, as a ZNF-specific coregulator essential for embryonic development in mice and associated with developmental syndromes in humans. We also identified ZFP91 as a representative Zincore client, binding the conserved promoter motif CTTTAAR. Cryo–electron microscopy of a Zincore-ZFP91-DNA complex revealed a SEPHS1 arginine clamp to recognize the DNA-bound zinc finger domains. This mode of binding explains recognition of different ZNFs and stabilizes ZFP91 onto its cognate DNA motif. Thus, our study identified Zincore as a ZNF-specific coregulator essential for development, involving a distinctive mechanism that locks ZNFs onto DNA and regulates transcription.</div>","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6755","pages":""},"PeriodicalIF":44.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorine-free strongly dipolar polymers exhibit tunable ferroelectricity","authors":"Jiahao Huang,&nbsp;Guanchun Rui,&nbsp;Yueming Yan,&nbsp;Elshad Allahyarov,&nbsp;Man-Hin Kwok,&nbsp;Wenyi Zhu,&nbsp;Li Li,&nbsp;Shixian Zhang,&nbsp;Zhiliang Pan,&nbsp;Deyu Li,&nbsp;Honghu Zhang,&nbsp;Richard R. Mu,&nbsp;Bin Zhao,&nbsp;Qing Wang,&nbsp;Philip L. Taylor,&nbsp;Richard F. Haglund,&nbsp;Q. M. Zhang,&nbsp;Lei Zhu","doi":"10.1126/science.ads4702","DOIUrl":"10.1126/science.ads4702","url":null,"abstract":"<div >Current research on ferroelectric polymers centers predominantly on poly(vinylidene fluoride) (PVDF)–based fluoropolymers because of their superior performance. However, they are considered “forever chemicals” with environmental concerns. We describe a family of rationally designed fluorine-free ferroelectric polymers, featuring a polyoxypropylene main chain and disulfonyl alkyl side chains with a C3 spacer: −SO₂CH₂CHRCH₂SO₂− (R = −H or −CH₃). Both experimental and simulation results demonstrate that strong dipole-dipole interactions between neighboring disulfonyl groups induce ferroelectric ordering in the condensed state, which can be tailored by changing the R group: ferroelectric for R = −H or relaxor ferroelectric for R = −CH₃. At low electric fields, the relaxor polymer exhibits electroactuation and electrocaloric performance comparable with those of state-of-the-art PVDF-based tetrapolymers.</div>","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6755","pages":""},"PeriodicalIF":44.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Other Journals","authors":"Di Jiang,&nbsp;Jelena Stajic,&nbsp;Ian S. Osborne,&nbsp;Sarah Lemprière,&nbsp;Caroline Ash,&nbsp;Priscilla N. Kelly,&nbsp;Jack Huang","doi":"10.1126/science.aea2122","DOIUrl":"10.1126/science.aea2122","url":null,"abstract":"","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6755","pages":""},"PeriodicalIF":44.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/science.aea2122","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rejecting genetic essentialism","authors":"Santiago J. Molina","doi":"10.1126/science.adu5497","DOIUrl":"10.1126/science.adu5497","url":null,"abstract":"","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6755","pages":""},"PeriodicalIF":44.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supporting scientists who study and work abroad","authors":"Tanmoy Chakraborty,&nbsp;Hager Khaled Mekkawy,&nbsp;Karen Jacqueline Cloete,&nbsp;Ranjeet Singh Mahla,&nbsp;Dandan Peng,&nbsp;Arturo Perez,&nbsp;Nora Rouabah,&nbsp;Joseph Flavian Gomes,&nbsp;Fotini Drallou,&nbsp;Tyseer Abdalrahman,&nbsp;Julio Santos,&nbsp;Vini Tiwari,&nbsp;Teng-Jui Lin,&nbsp;Shihao He,&nbsp;Jan Kadlec,&nbsp;Fatma Betul Dincaslan,&nbsp;Yana Suchikova,&nbsp;Zelong Lu,&nbsp;JiaHao Shi,&nbsp;Ankita Gupta,&nbsp;Andressa Monteiro Venturini,&nbsp;Hagar Abousidara,&nbsp;Alaa Mostafa,&nbsp;Anna Uzonyi,&nbsp;Ali Saber,&nbsp;Yan Ge,&nbsp;Howard Lopes Ribeiro Jr.","doi":"10.1126/science.aea0626","DOIUrl":"10.1126/science.aea0626","url":null,"abstract":"","PeriodicalId":21678,"journal":{"name":"Science","volume":"389 6755","pages":""},"PeriodicalIF":44.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/science.aea0626","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}