Functional Foods - Phytochemicals and Health Promoting Potential最新文献

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Role of Functional Food in Treating and Preventing Cardiovascular Diseases 功能食品在治疗和预防心血管疾病中的作用
Functional Foods - Phytochemicals and Health Promoting Potential Pub Date : 2021-11-10 DOI: 10.5772/intechopen.96614
Mpho Edward Mashau, Shonisani Eugenia Ramashia
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引用次数: 1
Theoretical Studies on Anti-Oxidant Activity of the Phytochemical, Coumestrol and Its Derivatives 植物化学甘美醇及其衍生物抗氧化活性的理论研究
Functional Foods - Phytochemicals and Health Promoting Potential Pub Date : 2021-11-10 DOI: 10.5772/intechopen.96967
P. Vinduja, K. Muraleedharan
{"title":"Theoretical Studies on Anti-Oxidant Activity of the Phytochemical, Coumestrol and Its Derivatives","authors":"P. Vinduja, K. Muraleedharan","doi":"10.5772/intechopen.96967","DOIUrl":"https://doi.org/10.5772/intechopen.96967","url":null,"abstract":"Free radical-induced changes in cellular and organ levels have been studied as a possible underlying cause of various adverse health conditions. Important research efforts have, therefore, been made to discover more powerful and potent antioxidants/free radical scavengers for the treatment of these adverse conditions. The phytoestrogen coumestrol intensively attracted scientific interest due to their efficient pharmacological activities. In this scenario, DFT studies were carried out to test the antiradical activities of coumestrol and its derivatives. The results obtained from FEDAM plots demonstrated that the coumestrol derivatives pointed out were good radical scavengers relative to the parent molecule in the gas phase. The derivatives whose 16thposition substituted with electron-donating groups like -NH2, -OCH3 and -CH3 showed good antioxidant capacity. Three antioxidant mechanisms, including hydrogen atom transfer (HAT), electron transfer followed by proton transfer (SET-PT), and sequential proton loss electron transfer (SPLET), were investigated by measuring thermodynamic parameters.","PeriodicalId":346836,"journal":{"name":"Functional Foods - Phytochemicals and Health Promoting Potential","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131836782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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