Experimental Aging Research最新文献_第9页

The QuadMax Task: Parametrically Manipulating Associative Memory Load across the Adult Lifespan. QuadMax任务:在成人寿命中参数化地操纵联想记忆负荷。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-07-01 DOI: 10.1080/0361073X.2022.2115740

Corinna Y Franco, Alexander Alcaraz-Torres, Ilana J Bennett

{"title":"The QuadMax Task: Parametrically Manipulating Associative Memory Load across the Adult Lifespan.","authors":"Corinna Y Franco, Alexander Alcaraz-Torres, Ilana J Bennett","doi":"10.1080/0361073X.2022.2115740","DOIUrl":"https://doi.org/10.1080/0361073X.2022.2115740","url":null,"abstract":"Adults of all ages are worse at recognizing pairs of items that were previously seen together relative to the individual items, and this paired-associative memory deficit is exacerbated in aging. Less is known about memory for higher associative loads, which place greater demands on binding processes that link items into a cohesive memory trace, among other processes (e.g., working memory, recollection). In this study, adults across the lifespan (n = 250, 18-78 years) completed a novel recognition task in which they studied word pairs, triplets, and quadruplets and were tested on their memory for repeated, recombined, and novel word sets. Associative memory deficits were seen in adults of all ages as fewer correct responses to repeated sets (hits), more incorrect responses to recombined sets (recombined false alarm, FA), and larger differences between these measures (associative memory) at higher set sizes. In addition, older adults had worse associative memory performance (higher recombined FA, lower associative memory) that increased at higher set sizes. These findings indicate that associative memory deficits increase with demands on binding or other processes at higher associative loads and with aging. They further demonstrate the feasibility of manipulating and assessing associative memory load using our novel QuadMax task.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9877272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reduced Olfactory Memory Performance Is Associated with Executive Function Deficits in Older Adults. 老年人嗅觉记忆能力下降与执行功能缺陷有关。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-07-01 DOI: 10.1080/0361073X.2022.2122651

Carina Schlintl, Anne Schienle

{"title":"Reduced Olfactory Memory Performance Is Associated with Executive Function Deficits in Older Adults.","authors":"Carina Schlintl, Anne Schienle","doi":"10.1080/0361073X.2022.2122651","DOIUrl":"https://doi.org/10.1080/0361073X.2022.2122651","url":null,"abstract":"Introduction: Previous research has identified an association between olfactory impairment (reduced odor sensitivity/ identification/ discrimination) and cognitive impairment in older adults. The present study focused on the relationship between olfactory memory performance and cognitive/affective functioning.Method: Recognition performance for olfactory and visual stimuli (control condition) was tested through a matching task in older adults (n = 44; Mage = 76 years) and younger adults (n = 56; Mage = 24 years). Additionally, negative affect (anxiety, depression) and cognitive functioning were assessed via validated questionnaires and a neuropsychological test battery.Results: The older participants performed worse than the younger adults in the olfactory memory task. In older adults, difficulties in remembering odors were associated with reduced odor identification and executive functioning (reduced cognitive flexibility). Affective well-being was not related to olfactory memory performance.Implication: Olfactory memory impairment in older adulthood might be a marker for cognitive decline in areas related to executive functions.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9877283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Psychometric Properties of the Turkish Version of the Fear of Falling Questionnaire-Revised (FFQ-R) in Nursing Home Residents with Mild Cognitive Decline. 轻度认知衰退的养老院居民土耳其语版跌倒恐惧问卷(FFQ-R)的心理测量特征

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-07-01 DOI: 10.1080/0361073X.2022.2106716

Fatih Özden, Zeynep Yıldız Kızkın, Mehmet Özkeskin

{"title":"Psychometric Properties of the Turkish Version of the Fear of Falling Questionnaire-Revised (FFQ-R) in Nursing Home Residents with Mild Cognitive Decline.","authors":"Fatih Özden, Zeynep Yıldız Kızkın, Mehmet Özkeskin","doi":"10.1080/0361073X.2022.2106716","DOIUrl":"https://doi.org/10.1080/0361073X.2022.2106716","url":null,"abstract":"Background: The aim of the study was to investigate the validity and reliability of the Turkish version of the Fear of Falling Questionnaire-Revised (FFQ-R) in older adults with mild cognitive impairment (MCI) living in a nursing home.Methods: The study was conducted with 107 (69 women) older adults. The participants were evaluated with the FFQ-R, the Falls Efficacy Scale (FES), the Mini-Mental State Examination (MMSE), the Barthel Index and Montgomery-Åsberg Depression Rating Scale (MADRS)\". FFQ-R was refilled one month later for retesting.Results: Cronbach's alpha value of the FFQ-R was 0.971. The global internal consistency was excellent (>0.80). Intraclass correlation coefficient of the FFQ-R was 0.962 (95% CI: 0.92-0.98), indicating excellent test-retest reliability. The Standard Error of Measurement (SEM) and Minimal Detectable Change (MDC) values of the FFQ-R was 0.80 and 2.21, respectively. The correlation between the total score of FFQ-R and the FES was excellent (r = 0.963, p < .001). The relationship between FFQ-R and MMSE was excellent (r = -0.821, p < .001). Besides, there was a moderate correlation between the FFQ-R with Barthel Index (r = -0.648, p < .001) and FFR-Q with MADRS (r = 0.568, p < .001).Conclusion: Turkish version of the FFQ-R is a valid and reliable tool to assess the fear of falling in nursing home residents.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9508129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Musical Mnemonics on Working Memory Performance in Cognitively Unimpaired Young and Older Adults. 音乐助记法对认知功能健全的青年和老年人工作记忆表现的影响。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-07-01 DOI: 10.1080/0361073X.2022.2104061

Marije W Derks-Dijkman, Rebecca S Schaefer, Maartje L Stegeman, Ilse D A van Tilborg, Roy P C Kessels

引用次数: 2

Aerobic Training with Naringin Supplementation Improved Spatial Cognition via H₂S Signaling Pathway in Alzheimer's Disease Model Rats. 有氧训练加柚皮苷通过H2S信号通路改善阿尔茨海默病模型大鼠的空间认知

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-07-01 DOI: 10.1080/0361073X.2022.2101303

Mojtaba Salehpour, Ghorbangol Ashabi, Majid Kashef, Elahe Sadat Marashi, Tayyebeh Ghasemi

{"title":"Aerobic Training with Naringin Supplementation Improved Spatial Cognition via H2S Signaling Pathway in Alzheimer's Disease Model Rats.","authors":"Mojtaba Salehpour, Ghorbangol Ashabi, Majid Kashef, Elahe Sadat Marashi, Tayyebeh Ghasemi","doi":"10.1080/0361073X.2022.2101303","DOIUrl":"https://doi.org/10.1080/0361073X.2022.2101303","url":null,"abstract":"Objectives: This study examined the effects of one-month naringin administration and exercise training on cognitive impairment and H2S signaling pathway in an Amyloid β (Aβ)-injected rat.Methods: Rats were divided into four groups: control group; rats underwent Aβ microinjection surgery, exercise group; rats underwent Aβ microinjection surgery and trained by treadmill for four weeks, naringin group; rats underwent Aβ microinjection surgery, and rats orally administrated 80 mg.kg-1 naringin for four weeks, naringin+exercise group; rats underwent Aβ microinjection surgery and were trained by treadmill for four weeks, and also, rats orally administrated 80 mg.kg-1 naringin for four weeks. After one month of treatment, spatial learning and memory were measured, and then hippocampi were sampled. S-adenosylmethionine (SAM), cystathionine-β-synthase (CBS), hydrogen sulfide (H2S) levels, and neuronal death were detected in the hippocampi of rats.Results: Naringin and exercise improved spatial learning (latency time, P < .001) and memory (P < .001) in the Morris Water Maze test in Aβ-injected rats compared with the control group. SAM (P < .01), CBS (P < .001), and H2S (P < .01) levels are increased in the naringin+exercise group compared with the control group.Conclusion: The result of this study supports the effect of exercise and/or naringin to improve cognitive dysfunction and cell death through the production of H2S.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9499114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Mastering the Relationship between the Body and the Brain? The Case of a Female Master Athlete. 掌握身体和大脑的关系?一位女运动健将的案例。

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-07-01 DOI: 10.1080/0361073X.2022.2109340

Kathia Saillant, Brittany Intzandt, Béatrice Bérubé, Safa Sanami, Claudine Gauthier, Louis Bherer

{"title":"Mastering the Relationship between the Body and the Brain? The Case of a Female Master Athlete.","authors":"Kathia Saillant, Brittany Intzandt, Béatrice Bérubé, Safa Sanami, Claudine Gauthier, Louis Bherer","doi":"10.1080/0361073X.2022.2109340","DOIUrl":"https://doi.org/10.1080/0361073X.2022.2109340","url":null,"abstract":"Background: Physical inactivity significantly increases risk of cardiovascular diseases, which are highly prevalent in aging. Conversely, higher levels of physical activity in aging have been associated with benefits for physical and cognitive health and is hypothesized to prevent and reduce development of cardiovascular risk factors. However, those older adults with the highest activity levels (i.e., Master Athletes [MA]) are relatively understudied, and even fewer studies involve female MA.Objective: The aim of this study was to compare the physiological, physical, and cognitive profiles of an 83-year-old track-and-field MA runner to a sample of inactive age-matched females.Results: Results revealed the MA had a high peak oxygen uptake and had superior performance on visuospatial memory tasks compared to her inactive counterparts. Cerebral blood flow was slightly elevated in the MA, but lower cerebrovascular reactivity was revealed compared to the other female included in the magnetic resonance imaging portion.Conclusion: Our results suggest that high levels of physical activity have benefits on multiple aspects of an aging female's life and that more studies should include MA, as well as a spectrum of cardiorespiratory fitness to further understand the role of physical activity in female aging.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9499123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Overload and Emotional Wellbeing in a Sample of Spanish Caregivers of Alzheimer's Patients during COVID-19 pandemic. COVID-19大流行期间西班牙阿尔茨海默病患者护理人员样本中的超载和情绪健康

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-07-01 DOI: 10.1080/0361073X.2022.2115739

Álvaro Rodríguez-Mora, Tania Mateo Guirola, José M Mestre

{"title":"Overload and Emotional Wellbeing in a Sample of Spanish Caregivers of Alzheimer's Patients during COVID-19 pandemic.","authors":"Álvaro Rodríguez-Mora, Tania Mateo Guirola, José M Mestre","doi":"10.1080/0361073X.2022.2115739","DOIUrl":"https://doi.org/10.1080/0361073X.2022.2115739","url":null,"abstract":"Introduction: Carers of Alzheimer's suffer from caregiver overload, anxiety and depression. Changes in caregiving brought about by pandemic restrictions (COVID-19) may play a role. The aim was to explore the caregiver profile and assess the influence of the pandemic on informal and formal caregivers in a Spanish sample.Method: Sixty caregivers participated. An ad hoc questionnaire, ZBI, STAI and BDI were administered.Results: Informal caregivers were more overloaded, anxious and depressed than professional caregivers. Both groups perceived themselves to be more sad, worried and stressed than in the pre-pandemic situation. The pandemic-generated variables associated with caregiving did not influence caregiver overload in both groups. In informal caregivers, worsening of the patient with stress and changes in perceived social support with anxiety and depression. In professional caregivers, changes in routine were associated with stress and lower depression and changes in perceived social support with higher caregiver strain. Changes in caregiving routine and changes in perceived social support were predictors of overload and emotional distress in both caregivers.Conclusions: Overload was not influenced by the pandemic situation. Changes in caregiving routine and lack of social support were found to be predictors of overload and emotional distress in both types of caregivers.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive Reserve and Cognitive Functioning among Oldest Old Adults: Findings from the Georgia Centenarian Study. 高龄老人的认知储备和认知功能：佐治亚州百岁老人研究的结果。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2023-07-01 Epub Date: 2022-08-05 DOI: 10.1080/0361073X.2022.2106717

Peter Martin, Yasuyuki Gondo, Gina Lee, John L Woodard, L Steven Miller, Leonard W Poon

{"title":"Cognitive Reserve and Cognitive Functioning among Oldest Old Adults: Findings from the Georgia Centenarian Study.","authors":"Peter Martin, Yasuyuki Gondo, Gina Lee, John L Woodard, L Steven Miller, Leonard W Poon","doi":"10.1080/0361073X.2022.2106717","DOIUrl":"10.1080/0361073X.2022.2106717","url":null,"abstract":"Objectives: Living a long life does not guarantee the maintenance of optimal cognitive functioning; however, similar to older adults in general, cognitive reserve may also protect oldest-old adults from cognitive decline. The purpose of this study was to assess cognitive reserve among centenarians and octogenarians and to evaluate a process model of cognitive reserve.Methods: A total of 321 centenarians and octogenarians from the Georgia Centenarian Study were included in this study. Cognitive reserve components included level of education, occupational responsibility, current social engagement, past engaged lifestyle, and activity. Cognitive functioning was measured with the Mini-Mental Status Examination.Results: Structural equation modeling was computed, and the overall model fit well, χ2 (df = 3) = 5.02, p = .17; CFI = .99, RMSEA = .05. Education is directly and indirectly related to cognitive functioning through occupational responsibility and past engaged lifestyle. Current social engagement is related to cognitive functioning directly and indirectly through current activities. The four direct predictors (i.e., education, current social engagement, current activity, and past engaged lifestyle) explained 35% of the variance in cognitive functioning.Conclusion: The results provide important information for cognitive reserve theories with implications for interventions that build cognitive reserve.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9511226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Older Adult Health Condition as a Moderator of How Middle-Aged Adults' Ageist Attitudes and Aging Anxiety Relate to Their Compassion for and Emotional Distance from Older Adults. 老年人健康状况对中年人年龄歧视态度和衰老焦虑对老年人同情和情感距离的调节作用

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-05-01 DOI: 10.1080/0361073X.2022.2091329

Hannah M Bashian, Grace I L Caskie

{"title":"Older Adult Health Condition as a Moderator of How Middle-Aged Adults' Ageist Attitudes and Aging Anxiety Relate to Their Compassion for and Emotional Distance from Older Adults.","authors":"Hannah M Bashian, Grace I L Caskie","doi":"10.1080/0361073X.2022.2091329","DOIUrl":"https://doi.org/10.1080/0361073X.2022.2091329","url":null,"abstract":"Objectives: Using Terror Management Theory and Social Identity Theory as frameworks, we examined whether the relationship of aging anxiety to compassion for and emotional distance from older adults was mediated by ageist attitudes and whether an older adult's health condition moderated these relationships.Method: Using an experimental design, 292 middle-aged adults (40-55 years) were assigned to read a description of an older adult with Alzheimer's Disease (AD), prostate cancer, or who was healthy.Results: The relationship of aging anxiety to compassion was mediated by ageist attitudes in both the AD and prostate cancer conditions. More ageist attitudes related to less compassion more strongly for unhealthy older adult conditions than for the healthy older adult condition as well as for the AD condition compared to the cancer condition. Ageist attitudes related to more emotional distance from the older adult with AD than the older adult with cancer.Discussion: Older adults with AD may evoke a stronger relationship of ageist attitudes with emotions toward older adults. These findings extend previous research by examining middle-aged participants, a population often serving as caregivers to their aging relatives.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9249598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between Health Literacy and Frailty in Older Adults with Chronic Kidney Disease. 老年慢性肾病患者健康素养与虚弱的关系

IF 1.8 4区医学

Experimental Aging Research Pub Date : 2023-05-01 DOI: 10.1080/0361073X.2022.2068326

Burcu Candemir, Funda Yıldırım, Emre Yaşar, Yasemin Erten, Berna Göker

{"title":"Relationship between Health Literacy and Frailty in Older Adults with Chronic Kidney Disease.","authors":"Burcu Candemir, Funda Yıldırım, Emre Yaşar, Yasemin Erten, Berna Göker","doi":"10.1080/0361073X.2022.2068326","DOIUrl":"https://doi.org/10.1080/0361073X.2022.2068326","url":null,"abstract":"Background: Chronic kidney disease (CKD) is associated with an increased risk of frailty, morbidity, and mortality in older adults. Limited health literacy (HL) is a condition that can cause frailty in CKD. Frailty leads to a decreased resistance to stress situations caused by activities of daily living and increased morbidity and mortality. The aim of this study was to investigate the relationship between HL and frailty in older adults with stage 4-5 CKD.Methods: A total of 109 patients with stage 4-5CKD were included. All patients underwent a comprehensive geriatric assessment. Health literacy was assessed by the Turkish version of the European Health Literacy Questionnaire. Frailty status was measured using the Fried Frailty Index.Results: The median age was 72 (68-80) years and 72 patients (66.1%) had lowHL. Forty-six patients (42.2%) were frail, and frailty was more common in the low HL group.Conclusion: The present study demonstrated that low HL level was common in geriatric patients with stage 4-5 CKD and was associated with frailty, as well as a decrease in daily and instrumental life activities, decrease in acceptance of illness scale, and compliance with medical treatment.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9242246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1