晚年抑郁症的证据:抑郁症状、运动、呼吸困难和认知之间的复杂关系。

IF 1.4 4区 医学 Q4 GERIATRICS & GERONTOLOGY
Experimental Aging Research Pub Date : 2024-05-01 Epub Date: 2023-04-10 DOI:10.1080/0361073X.2023.2196504
Martino Belvederi Murri, Federico Triolo, Alice Coni, Erika Nerozzi, Pasqualino Maietta Latessa, Silvia Fantozzi, Nicola Padula, Andrea Escelsior, Barbara Assirelli, Giuliano Ermini, Luigi Bagnoli, Donato Zocchi, Aderville Cabassi, Stefano Tedeschi, Giulio Toni, Rabih Chattat, Ferdinando Tripi, Francesca Neviani, Marco Bertolotti, Alessandro Cremonini, Klea D Bertakis, Mario Amore, Lorenzo Chiari, Stamatula Zanetidou
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引用次数: 0

摘要

背景:身体症状在晚年抑郁症中起着重要作用,并可能导致抗抑郁治疗后的残留症状。在这项探索性研究中,我们研究了特定身体维度在老年抑郁症患者中的作用,包括运动、呼吸功能、跌倒恐惧、认知和身体虚弱:方法:在基层医疗精神咨询联络项目中,临床稳定的老年重度抑郁症患者接受了抑郁症状、器械运动分析、呼吸困难、虚弱、活动受限、认知功能和跌倒恐惧的综合评估。研究人员进行了网络分析,以探索各临床维度之间的独特调整关联:结果:悲伤与翻身和行走能力以及从走到坐的运动转换能力下降有关,也与一般认知能力下降有关。悲伤还与呼吸困难有关,而神经肌肉抑郁负担则与活动受限有关:讨论:运动和认知功能受限、呼吸困难和虚弱可能会导致晚年抑郁症的残留症状持续存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The body of evidence of late-life depression: the complex relationship between depressive symptoms, movement, dyspnea and cognition.

Background: Physical symptoms play an important role in late-life depression and may contribute to residual symptomatology after antidepressant treatment. In this exploratory study, we examined the role of specific bodily dimensions including movement, respiratory functions, fear of falling, cognition, and physical weakness in older people with depression.

Methods: Clinically stable older patients with major depression within a Psychiatric Consultation-Liaison program for Primary Care underwent comprehensive assessment of depressive symptoms, instrumental movement analysis, dyspnea, weakness, activity limitations, cognitive function, and fear of falling. Network analysis was performed to explore the unique adjusted associations between clinical dimensions.

Results: Sadness was associated with worse turning and walking ability and movement transitions from walking to sitting, as well as with worse general cognitive abilities. Sadness was also connected with dyspnea, while neurovegetative depressive burden was connected with activity limitations.

Discussion: Limitations of motor and cognitive function, dyspnea, and weakness may contribute to the persistence of residual symptoms of late-life depression.

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来源期刊
Experimental Aging Research
Experimental Aging Research 医学-老年医学
CiteScore
3.60
自引率
0.00%
发文量
68
审稿时长
>12 weeks
期刊介绍: Experimental Aging Research is a life span developmental and aging journal dealing with research on the aging process from a psychological and psychobiological perspective. It meets the need for a scholarly journal with refereed scientific papers dealing with age differences and age changes at any point in the adult life span. Areas of major focus include experimental psychology, neuropsychology, psychobiology, work research, ergonomics, and behavioral medicine. Original research, book reviews, monographs, and papers covering special topics are published.
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