阿尔茨海默氏症患者从未预见到的分词中获得语义引物

IF 1.4 4区医学 Q4 GERIATRICS & GERONTOLOGY

Experimental Aging Research Pub Date : 2024-07-01 Epub Date: 2023-04-23 DOI:10.1080/0361073X.2023.2195294

Julie A Higgins, William Milberg, Regina McGlinchey

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引用次数: 0

摘要

研究问题阿尔茨海默病（AD）的语义障碍是否部分是由于空间注意力缺陷造成的？在目标检测任务中，老年人（OA）和注意力缺失症患者都会受到有效空间线索的影响，但与中性相比，只有OA会受到无效线索的影响。在阅读任务中，空间线索会有效或无效地提示图片的位置，这些图片与随后集中呈现的单词相关或无关。OA只在有效提示后才表现出语义引物，而AD个体在有效和无效提示后都表现出语义引物：讨论：不能抑制未提示的位置会导致注意力缺失症患者处理潜在的干扰语义信息。

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Semantic Priming from Uncued Distractors in Alzheimer's Disease.

Research question: Are semantic impairments in Alzheimer's disease (AD) partially due to deficits in spatial attention?

Methods and results: In a target detection task, both older adults (OAs) and AD individuals were facilitated by valid spatial cues, but only OAs were impaired by invalid cues compared to neutral. In a reading task, spatial cues validly or invalidly cued the location of pictures, which were related or unrelated to subsequent, centrally presented, words. OAs showed semantic priming only after valid cues, whereas AD individuals showed priming after valid and invalid cues.

Discussion: Failure to inhibit uncued locations results in processing of potentially distracting semantic information in AD.

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来源期刊

Experimental Aging Research 医学-老年医学

CiteScore

3.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Experimental Aging Research is a life span developmental and aging journal dealing with research on the aging process from a psychological and psychobiological perspective. It meets the need for a scholarly journal with refereed scientific papers dealing with age differences and age changes at any point in the adult life span. Areas of major focus include experimental psychology, neuropsychology, psychobiology, work research, ergonomics, and behavioral medicine. Original research, book reviews, monographs, and papers covering special topics are published.