Health systems and reform Pub Date : 2025-12-31 Epub Date: 2025-06-30 DOI: 10.1080/23288604.2025.2521185

Koji Yamawaki, Aya Goto, Kimiko Ueda

{"title":"Improving Care for Preschool Children with Disabilities During Disasters in Japan.","authors":"Koji Yamawaki, Aya Goto, Kimiko Ueda","doi":"10.1080/23288604.2025.2521185","DOIUrl":"https://doi.org/10.1080/23288604.2025.2521185","url":null,"abstract":"This commentary traces the origins of Japan's special education system and explores the need to equip preschool teachers with the specific knowledge and skills necessary to care for children under the age of six with disabilities during disasters in Japan. Japan's slow implementation of inclusive education, in which children with and without disabilities are educated together, was noted by the UN Committee on the Rights of Persons with Disabilities in 2022. The Committee also recommended improved care for persons with disabilities in disaster situations and humanitarian emergencies. Historically, Japan has promoted policies that segregate children with disabilities from children without disabilities. Integrated childcare began in the 1970s, but there continues to be a lack of suitable systems and practical guidelines for disaster management in inclusive childcare. The curricula of institutions that train childcare professionals were reviewed. As of April 1, 2023, there were 666 designated childcare teacher training institutions in Japan. Of these, 498 training institutions offered courses to obtain both kindergarten and nursery teaching licenses. Thirty-seven of the institutions were national and public schools, of which the present study included 36 schools whose syllabus was available online and whose course content could be confirmed. Only one school (2.8%) was found to include \"disaster and childcare\" in its curriculum, and three schools (8.3%) included \"safety of children with disabilities\" in their curriculum. Specialist disaster preparedness training to enable teachers to care for preschool children with disabilities in the event of a disaster is critical in the context of inclusive childcare.","PeriodicalId":73218,"journal":{"name":"Health systems and reform","volume":"11 1","pages":"2521185"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rethinking Trust and Public Health Compliance: Introducing a Trust Continuum for Policy and Practice. 重新思考信任和公共卫生合规：为政策和实践引入信任连续体。

Health systems and reform Pub Date : 2025-12-31 Epub Date: 2025-02-11 DOI: 10.1080/23288604.2025.2457239

Ashley Fox, Victoria Y Fan, Heeun Kim, Minah Kang

引用次数: 0

How Health Systems World-wide Fail Type 2 Diabetics. 全球卫生系统如何使2型糖尿病患者失败？

Health systems and reform Pub Date : 2025-12-31 Epub Date: 2025-01-23 DOI: 10.1080/23288604.2024.2437898

Abdo S Yazbeck, Son Nam Nguyen, Maria-Luisa Escobar

引用次数: 0

The Diabetes Care Cascade in Sri Lanka: An Analysis of Losses, Disparities, and Opportunities for Improved Health System Outcomes. 斯里兰卡的糖尿病护理级联：损失、差异和改善卫生系统结果的机会分析。

Health systems and reform Pub Date : 2025-12-31 Epub Date: 2025-06-23 DOI: 10.1080/23288604.2025.2516904

Ravindra P Rannan-Eliya, Nilmini Wijemunige, H M M Herath, Prasadini Perera, Vajira H W Dissanayake, Bilesha Perera, Shanti Dalpatadu, Sarath Samarage, Anuji Gamage

{"title":"The Diabetes Care Cascade in Sri Lanka: An Analysis of Losses, Disparities, and Opportunities for Improved Health System Outcomes.","authors":"Ravindra P Rannan-Eliya, Nilmini Wijemunige, H M M Herath, Prasadini Perera, Vajira H W Dissanayake, Bilesha Perera, Shanti Dalpatadu, Sarath Samarage, Anuji Gamage","doi":"10.1080/23288604.2025.2516904","DOIUrl":"10.1080/23288604.2025.2516904","url":null,"abstract":"Sri Lanka has one of the highest prevalence rates of diabetes, and improving diabetes control is a national priority. The care cascade framework, a tool for evaluating diabetes control and identifying system gaps, has not been assessed nationally in Sri Lanka. This study addresses this gap using data from a nationally representative longitudinal cohort. Using 2018-2019 data from the Sri Lanka Health and Ageing Study (SLHAS), we evaluated the diabetes care cascade, estimating levels of (i) prevalence, (ii) testing, (iii) diagnosis, (iv) awareness, (v) treatment, (vi) medication adherence, and (vii) control. Logistic regression assessed factors associated with step performance, and concentration indices quantified socioeconomic inequalities. Performance was benchmarked against other countries. In 4,827 participants the weighted diabetes prevalence was 23.2%. Of those with diabetes, 86.0% had been tested, 62.3% diagnosed, 58.6% aware, 44.7% treated, and 20.6% (hemoglobin A1c, HbA1c < 8.0%) and 12.4% (HbA1c < 7.0%) controlled. Older adults and those with hypertension achieved higher rates at all steps, while disparities by gender, education, location, and body mass index were minimal. Concentration indices confirmed pro-rich inequity from testing to treatment but revealed no significant inequity in control. Sri Lanka outperforms most low- and middle-income countries (LMICs) in testing, diagnosis, treatment, and disparities in coverage, reflecting underlying system strengths. But only one in five Sri Lankans with diabetes achieve control, with significant losses post-treatment. High diagnosis and treatment rates alone are insufficient; strategy must shift toward understanding the reasons for poor control. and improving treatment outcomes, a lesson with wider relevance.","PeriodicalId":73218,"journal":{"name":"Health systems and reform","volume":"11 1","pages":"2516904"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Qatar's Progress in Curbing Diabetes: A Comprehensive and Proactive Approach. 卡塔尔在控制糖尿病方面的进展：全面和积极的方法。

Health systems and reform Pub Date : 2025-12-31 Epub Date: 2025-06-23 DOI: 10.1080/23288604.2025.2516897

Mohamed Hamad J T Al-Thani, Sameh El-Saharty, Zeina Jamal, Amit Mishra, Suresh Babu Kokku, Rehana Nasir Nawaz, Ioanna Skaroni, Abdul Badi Abou-Samra

{"title":"Qatar's Progress in Curbing Diabetes: A Comprehensive and Proactive Approach.","authors":"Mohamed Hamad J T Al-Thani, Sameh El-Saharty, Zeina Jamal, Amit Mishra, Suresh Babu Kokku, Rehana Nasir Nawaz, Ioanna Skaroni, Abdul Badi Abou-Samra","doi":"10.1080/23288604.2025.2516897","DOIUrl":"https://doi.org/10.1080/23288604.2025.2516897","url":null,"abstract":"This commentary examines Qatar's proactive approach to addressing the rising prevalence of Type 2 diabetes mellitus and associated non-communicable diseases within the Gulf Cooperation Council region. Following the 2012 STEPwise survey, which revealed a T2DM prevalence of 16.7%, Qatar launched the National Diabetes Strategy (2016-2022), focusing on six strategic pillars. Recent data from the 2023 STEPwise survey indicates a stabilization in diabetes (18.1%) and obesity (33.4%) rates, alongside other lifestyle factors, necessitating ongoing public health interventions. Qatar leverages innovative technologies and digital health initiatives to enhance diabetes care and disease surveillance. The establishment of national taskforces for obesity and childhood diabetes further exemplifies Qatar's commitment to a coordinated response. Future directions include the National Health Strategy (NHS-3): Action Plan 2024-2030, on Obesity, Diabetes, and Modifiable Risk Factors for Atherosclerotic Cardiovascular Diseases, which aims to strengthen screening and management activities. By fostering partnerships and prioritizing research, Qatar aspires to improve health outcomes and serve as a model for other nations facing similar health challenges.","PeriodicalId":73218,"journal":{"name":"Health systems and reform","volume":"11 1","pages":"2516897"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A century of Azospirillum: plant growth promotion and agricultural promise. 一个世纪的氮螺旋藻：促进植物生长和农业前景。

IF 3.6

Plant signaling & behavior Pub Date : 2025-12-31 Epub Date: 2025-08-27 DOI: 10.1080/15592324.2025.2551609

Ramón Pelagio-Flores, Gustavo Ravelo-Ortega, Ernesto García-Pineda, José López-Bucio

{"title":"A century of Azospirillum: plant growth promotion and agricultural promise.","authors":"Ramón Pelagio-Flores, Gustavo Ravelo-Ortega, Ernesto García-Pineda, José López-Bucio","doi":"10.1080/15592324.2025.2551609","DOIUrl":"https://doi.org/10.1080/15592324.2025.2551609","url":null,"abstract":"The genus Azospirillum celebrates 100 y since its discovery in 1925 by Martinus Willem Beijerinck, who worked with Spirillum lipoferum as a starting species. Decades of work involving laboratory and field research endorse their various beneficial properties, such as plant rooting, mineral nutrition, hormonal strengthening, and the activation of cellular and molecular responses, which lead to better growth, development, and productivity. Some hormones, such as auxins and cytokinins, potentiate root branching through their effects on mitosis, and via signal transduction mediated by the Target Of Rapamycin (TOR) kinase. Although initial efforts were aimed at clarifying the importance of biological nitrogen fixation in plant growth in the face of root colonization with Azospirillum, recent advances show that these bacteria also activate the mechanisms of acquisition of phosphorus and iron, two essential nutrients for fulfilling the plant's life cycle. In recent years, Azospirillum structural elements such as flagellin and lipopolysaccharides emerged as elicitors, influencing the development and defense of the host. Goals have also been achieved in formulating biotechnological products, whose application has increased in countries such as Argentina and Brazil, showing relevant and promising results toward saving fertilizer, optimizing management, and ultimately, making agriculture more sustainable.","PeriodicalId":94172,"journal":{"name":"Plant signaling & behavior","volume":"20 1","pages":"2551609"},"PeriodicalIF":3.6,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Levels of extracellular ATP in growth zones of Arabidopsis primary roots are changed by altered expression of apyrase enzymes. 拟南芥初生根生长期细胞外ATP水平的变化是由apyrase酶表达改变引起的。

IF 3.6

Plant signaling & behavior Pub Date : 2025-12-31 Epub Date: 2025-09-17 DOI: 10.1080/15592324.2025.2555965

Greg Clark, Diana Vanegas, Ashley Cannon, Miranda Jankovik, Ryan Huang, Katherine A Brown, Eric McLamore, Stanley J Roux

{"title":"Levels of extracellular ATP in growth zones of Arabidopsis primary roots are changed by altered expression of apyrase enzymes.","authors":"Greg Clark, Diana Vanegas, Ashley Cannon, Miranda Jankovik, Ryan Huang, Katherine A Brown, Eric McLamore, Stanley J Roux","doi":"10.1080/15592324.2025.2555965","DOIUrl":"https://doi.org/10.1080/15592324.2025.2555965","url":null,"abstract":"In both animal and plant cells extracellular nucleotides act as hormone-like signals regulating many important physiological and developmental responses. In plants, many of these responses have been studied in roots. Here we used an enzyme-based microsensor to measure the concentrations of extracellular ATP (eATP) within 2 µm of epidermal cell surfaces in growth zones of primary roots of wild-type and transgenic Arabidopsis seedlings. The concentration of eATP outside of growing wild-type roots was in the nanomolar range and was highest in in the elongation zone. The concentrations of eATP in wild-type roots were altered in two kinds of mutants, those that were overexpressing AtAPY1 or AtAPY2, which encode apyrases (NTPDases) that regulate root and root hair growth, and those that were suppressed in the expression of these two transcripts. Our results indicate that the [eATP] measured varies inversely with the level of expression of these apyrases. Structural modeling of these two apyrases predicts active site configurations capable of binding ATP. Taken together these results favor the hypothesis that AtAPY1 and AtAPY2 regulate eATP levels in primary roots.","PeriodicalId":94172,"journal":{"name":"Plant signaling & behavior","volume":"20 1","pages":"2555965"},"PeriodicalIF":3.6,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colon lesions in elderly individuals with positive and negative fecal immunochemical test results among PERSIAN Guilan cohort study (PGCS) population. 波斯桂兰队列研究（PGCS）人群中粪便免疫化学试验结果阳性和阴性的老年人结肠病变

IF 1

Caspian Journal of Internal Medicine Pub Date : 2025-12-24 eCollection Date: 2025-01-01 DOI: 10.22088/cjim.16.3.451

Heydar Ali Balou, Farahnaz Joukar, Mahdi Orang Goorabzarmakhi, Milad Shahdkar, Soheil Hassanipour, Saman Maroufizadeh, Mehrnaz Asgharnezhad, Paridokht Karimian, Fariborz Mansour-Ghanaei

{"title":"Colon lesions in elderly individuals with positive and negative fecal immunochemical test results among PERSIAN Guilan cohort study (PGCS) population.","authors":"Heydar Ali Balou, Farahnaz Joukar, Mahdi Orang Goorabzarmakhi, Milad Shahdkar, Soheil Hassanipour, Saman Maroufizadeh, Mehrnaz Asgharnezhad, Paridokht Karimian, Fariborz Mansour-Ghanaei","doi":"10.22088/cjim.16.3.451","DOIUrl":"10.22088/cjim.16.3.451","url":null,"abstract":"Background: Early colorectal cancer (CRC) detection helps reduce the mortality rate. This study aimed to investigate colon lesions in individuals with positive and negative fecal immunochemical test (FIT) results among the (PERSIAN) Guilan cohort study (PGCS) population.Methods: This cross-sectional study was conducted on 1158 participants over 50 who were volunteers for the FIT stool test at the Endoscopy Department of Razi Hospital, Rasht, Iran, from 2021 to 2022. The FIT test was screened for all participants, and for 172 individuals (86 individuals from each group with positive and negative FIT results), a colonoscopy was performed to investigate the colon lesions. Demographic/clinical characteristics, FIT results, colonoscopy findings, and the Bristol Stool Chart were completed. All data were analyzed using SPSS Version 16, considering a significant level<0.05.Results: Out of 1,158 participants, 86 had positive FIT results, and 172 (52.3%) were females. The colonoscopy results showed that 34.3% of the patients had colon lesions. Individuals with positive FIT exhibited a significantly higher prevalence of colon lesions (p<0.001). No statistically significant differences were observed between positive and negative FIT results, demographic and clinical characteristics, and the location of lesions in individuals with colon lesions (p>0.05). Moreover, there was a significant difference in pathological findings and the presence of adenomatous polyps regarding the FIT results (p<0.001).Conclusion: The effectiveness of FIT in the initial stages of screening for early lesion detection is considerable, especially for individuals with upper age.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"16 3","pages":"451-457"},"PeriodicalIF":1.0,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the bioremediation of methylene blue by Haematococcus pluvialis through synchrotron-FTIR imaging and spectroscopy. 雨红球菌对亚甲基蓝生物修复的同步红外成像与光谱研究。

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Pub Date : 2025-12-15 Epub Date: 2025-06-24 DOI: 10.1016/j.saa.2025.126613

Jinghua Liu, Wenzhe Li, Xuanyi Ren, Zeming Qi, Jingwen Ma, Shan Huang, Lishuan Chai, Yue Jiao, Jiawei Xu, Xueqin Liu

{"title":"Study on the bioremediation of methylene blue by Haematococcus pluvialis through synchrotron-FTIR imaging and spectroscopy.","authors":"Jinghua Liu, Wenzhe Li, Xuanyi Ren, Zeming Qi, Jingwen Ma, Shan Huang, Lishuan Chai, Yue Jiao, Jiawei Xu, Xueqin Liu","doi":"10.1016/j.saa.2025.126613","DOIUrl":"10.1016/j.saa.2025.126613","url":null,"abstract":"Methylene blue (MB), as a phenothiazine dye, causes a harmful damage to health and receives increasingly more environmental concern. Herein, the batch experiments for MB biosorption and biotransformation by Haematococcus pluvialis were carried out to evaluate the optimal parameters of MB removal. In this work, we found that the maximum removal efficiency was attained when MB was at the initial concentration of 5 mg/L. Meanwhile, the cellular numbers and pigments decreased dramatically with the rising content of MB. Furthermore, synchrotron-FTIR microscopic imaging is employed here to investigate the interaction between MB dye and algal cells by the measurement of the various vital changes of cellular components involving in the bioremediation of the hazardous dye, which indicated that MB dye as a photosensitizer can trigger the algal transformation from vegetative cells into red cysts by introducing oxidative stress. Accordingly, the dye removal efficiency can be sharply enhanced by the transformed algal cells for the accumulation of astaxanthin or carotenoids. In addition, the FTIR spectroscopy combined with PCA algorithm was further utilized to discriminate various algal status based on their spectral features. As a result, it demonstrates that microscopic imaging and FTIR spectroscopy is a powerful and useful tool to elucidate underlying mechanisms of dye removal by algal cells at high spatial resolution and to evaluate cellular physiological characteristics through multivariate statistical analysis, and it even provides a novel and effective strategy to rapidly screen the potential microalgae for the removal of recalcitrant dyes from wastewater.","PeriodicalId":94213,"journal":{"name":"Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy","volume":"343 ","pages":"126613"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of adolescent acne vulgaris on CDLQI and DFIS: What does it depend on? 青少年寻常性痤疮对CDLQI和DFIS的影响：取决于什么？

IF 0.9

Northern clinics of Istanbul Pub Date : 2025-12-13 eCollection Date: 2025-01-01 DOI: 10.14744/nci.2023.45336

Defne Ozkoca, Nazli Caf, Tugba Kevser Uzuncakmak, Aysenur Ozdil, Ayse Nilhan Atsu

{"title":"The impact of adolescent acne vulgaris on CDLQI and DFIS: What does it depend on?","authors":"Defne Ozkoca, Nazli Caf, Tugba Kevser Uzuncakmak, Aysenur Ozdil, Ayse Nilhan Atsu","doi":"10.14744/nci.2023.45336","DOIUrl":"10.14744/nci.2023.45336","url":null,"abstract":"Objective: Acne vulgaris is a chronic and common disease among adolescents. The effects of acne vulgaris on the caregiver's quality of life and its relationship to patient's quality of life have been seldom studied. This study aims to investigate impact of adolescent acne vulgaris on the patients' and their caregivers' quality of life and to evaluate the relationship between these two variables.Methods: Acne vulgaris patients aged between 10 and 18 years and their caregivers were included in this prospective study. CDLQI (Children Dermatologic Quality of Life Index) and DFIS (Dermatological Family Impact Scale) questionnaires were used to assess the impact of acne vulgaris on the quality of life of patients and caregivers. SPSS version 21 was used for the statistical analysis; Spearman correlation test and Mann Whitney U test were used.Results: This study has shown a significant correlation between DFIS and CDLQI, between severity of acne and CDLQI, and between the previous use of systemic antibiotics and DFIS. There is no relationship of age, sex, disease duration, number of siblings, amount of money spent and previous treatment modalities to CDLQI. There is no relationship between age, sex, acne severity, disease duration, number of children and amount of money spent on DFIS.Conclusion: Acne vulgaris not only has an impact on the patient's quality of life but also on the caregiver's quality of life, which in turn affects the patient's quality of life.","PeriodicalId":94347,"journal":{"name":"Northern clinics of Istanbul","volume":"12 1","pages":"76-82"},"PeriodicalIF":0.9,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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