化学•材料最新文献

{"title":"Palladium-Catalyzed α-Arylation of Nitroalkanes with Aryl Fluorosulfonates for Convenient Access to α-Arylated Nitroalkanes","authors":"Chen-Long Zhu, Fei Zhao, Yuan-Yuan Wang, Xue-Qiang Chu, Hao Xu, Chengping Miao, Weidong Rao, Zhi-Liang Shen","doi":"10.1021/acs.joc.5c01502","DOIUrl":"https://doi.org/10.1021/acs.joc.5c01502","url":null,"abstract":"Palladium-catalyzed α-arylation of nitroalkanes by utilizing aryl fluorosulfonates as effective arylating agents can be realized. The reactions proceed effectively through C–O bond activation to produce a variety of valuable α-arylated nitroalkanes in modest to good yields with wide functional group compatibility. Additionally, late-stage functionalization of complex molecules and scale-up synthesis can be achieved.","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"27 1","pages":""},"PeriodicalIF":4.354,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144840273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vesicular drug delivery systems: A breakthrough in wound healing therapies","authors":"Amr Selim Abu Lila ,&nbsp;Mahmoud Mostafa ,&nbsp;Ahmed A. Katamesh ,&nbsp;Mohamed Ibrahim ,&nbsp;Shimaa M. Hassoun ,&nbsp;Marwa Mohamed El Sayed ,&nbsp;Gehad M. Subaiea ,&nbsp;Marwa H. Abdallah ,&nbsp;Milad Reda Qelliny","doi":"10.1016/j.colsurfb.2025.115046","DOIUrl":"10.1016/j.colsurfb.2025.115046","url":null,"abstract":"<div><div>The skin plays a crucial role in mediating the most significant transactions in our lives and is essential to our biology and sensory experiences. The skin is highly susceptible to developing various lesions, including ulcers and wounds, because it is constantly exposed to the external environment. Wounds can attenuate skin function, with subsequent complications and further severe implications. Wound healing is a crucial process and remains a complex biological process, often hindered by challenges such as infection, chronic inflammation, and impaired tissue regeneration. Conventional therapies, despite their widespread use, face limitations in terms of efficacy, targeted delivery, and patient compliance. The present review explores the main roles of lipid-based vesicular delivery systems, including ethosomes, liposomes, niosomes, novasomes, and solid lipid nanoparticles, as promising wound-healing delivery systems. A comprehensive analysis of wound classifications, key factors influencing the healing process, conventional and emerging novel therapeutic approaches, and the application of vesicular delivery systems in wound management was conducted. Additionally, the diverse bioactive agents transported through these systems were examined along with characterization techniques, challenges, scalability, and opportunities associated with their clinical translation. Furthermore, future directions in optimizing vesicular platforms for enhanced therapeutic efficacy and wound regeneration have been explored, highlighting the need for advanced strategies to overcome existing limitations and improve patient outcomes. This review underscores the transformative potential of vesicular systems for revolutionizing wound-healing therapies while addressing existing limitations and exploring pathways for future progress.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"256 ","pages":"Article 115046"},"PeriodicalIF":5.6,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144852486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life Cycle Greenhouse Gas Emissions and Mitigation Performances of Various Hydrogen Production Routes.","authors":"Lyu Zhang,Magnus Fröhling,Jingru Liu,Guangxin Liu,Lei Shi","doi":"10.1021/acs.est.5c03792","DOIUrl":"https://doi.org/10.1021/acs.est.5c03792","url":null,"abstract":"Hydrogen is widely recognized as a crucial element in the future energy transition to address climate change. However, the greenhouse gas (GHG) emissions associated with different hydrogen production routes vary, and there are still doubts about the GHG reduction potential of many routes. This study conducts a meta-analysis of 1283 assessment scenarios, reporting life cycle GHG emissions for 101 hydrogen production routes. Routes with notably low emissions are identified, such as biomass and biofuel utilization with carbon capture and storage (CCS), natural gas reforming with CCS, waste-derived hydrogen, and renewable energy-driven electrolysis. In contrast, biological routes show high variability, with some among the highest emitters. Background energy sources and feedstock composition are identified as key influencing factors. Additionally, 53 routes with emissions lower than steam methane reforming (SMR) are analyzed for substitution factors and levelized costs of GHG mitigation, with 17 routes emerging as promising options for GHG reduction, particularly those utilizing waste or biomass with CCS. Our findings highlight the need for localized strategies that optimize renewable resources and energy use to achieve cost-effective GHG reductions in hydrogen production.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"19 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144851231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massimo Olivucci: A Scientific Autobiography","authors":"Massimo Olivucci*,&nbsp;","doi":"10.1021/acs.jpcb.5c04288","DOIUrl":"https://doi.org/10.1021/acs.jpcb.5c04288","url":null,"abstract":"","PeriodicalId":60,"journal":{"name":"The Journal of Physical Chemistry B","volume":"129 32","pages":"8077–8086"},"PeriodicalIF":2.9,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144826260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Stability of Individual Carboxylate-Rich Alicyclic Molecules Under Simulated Environmental Irradiation and Microbial Incubation Conditions.","authors":"Alexander J Craig, Mahsa Norouzi, Paul Löffler, Foon Yin Lai, Rim Mtibaà, Eva Breyer, Federico Baltar, Lindon W K Moodie, Jeffrey A Hawkes","doi":"10.1021/acs.est.5c01958","DOIUrl":"https://doi.org/10.1021/acs.est.5c01958","url":null,"abstract":"<p><p>Understanding dissolved organic matter (DOM) relies on the development of methods capable of navigating its complexity. Although analytical techniques have continually advanced, the fate of individual compound classes remains nearly impossible to track with the current technology. Previously, we reported the synthesis of carboxylate-rich alicyclic molecule (CRAM) compounds that shared more similar analytical features with DOM than previously available standards. Here, we adopt an alternative approach to the conventional use of DOM as a bulk material by subjecting our synthesized CRAM compounds to simulated solar irradiation and microbial incubation experiments alongside molecules with chosen biological or chemical relevance. Irradiation experiments typically showed that compounds bearing only carboxylic acids and/or alcohols on a saturated carbon backbone were the most resistant to photochemical degradation but also that some of the investigated CRAM analogues were notably more stable in the presence of DOM. Within microbial incubations, all of our synthesized CRAMs were entirely stable after 8 months in various aquatic settings. These sets of experiments provide support for the proposed stability of CRAM within the environment as well as providing a platform from which a more diverse set of molecules can be used to assist in probing the stability of DOM.</p>","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144843804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Dynamics Simulations of Supercooled Aqueous Solutions of Calcium Perchlorate: Thermodynamics and Structure of Martian Solutes in TIP4P/2005 Water.","authors":"Paolo La Francesca, Paola Gallo","doi":"10.1021/acs.jpcb.5c03712","DOIUrl":"https://doi.org/10.1021/acs.jpcb.5c03712","url":null,"abstract":"<p><p>We employ molecular dynamics simulations to determine how calcium perchlorate modifies the phase diagram and structure of supercooled TIP4P/2005 water. These solutions are particularly relevant in light of recent experimental evidence of liquid water in perchlorate solutions underneath Martian soil. We focus on the interplay between its low-density liquid (LDL) and high-density liquid (HDL) phases, simulating solutions at concentrations of 3.15 and 25.7 wt%. Thermodynamic analysis confirms the persistence of several water anomalies, albeit shifted by the solutes. A second-order liquid-liquid critical point (LLCP) is observed at a concentration of 3.15 wt%. Structurally, radial distribution functions demonstrate that upon increasing the solute concentration, the HDL-like behavior is enhanced, as the thermodynamic LDL-like region appears to be shrinking. Calcium ions with perchlorate ions in water appear to be particularly effective at favoring supercooling.</p>","PeriodicalId":60,"journal":{"name":"The Journal of Physical Chemistry B","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144853952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atmosphere-pretreatment-induced structural reorganization of Al2O3-supported phosphorus oxynitride for enhanced catalytic activity in ethylbenzene direct dehydrogenation","authors":"Yuan Ma ,&nbsp;Baining Lin ,&nbsp;Chaojun Guo ,&nbsp;Yang Yang ,&nbsp;Chuli Shi ,&nbsp;Shuobin Fu ,&nbsp;Yonghua Zhou","doi":"10.1016/j.apcata.2025.120503","DOIUrl":"10.1016/j.apcata.2025.120503","url":null,"abstract":"<div><div>Non-metallic materials have attracted continuous interest in the direct dehydrogenation (DDH) of ethylbenzene due to their coke resistance and environmental friendliness. However, the catalytic activity was limited by the exposed density of active sites in non-metal catalysts. Herein, we report an atmosphere-pretreatment strategy using H₂ or O₂ at 350 ℃ to improve the exposure of active sites in Al₂O₃-supported phosphorus oxynitride (PNO) catalysts, thereby enhancing their catalytic performance in DDH of ethylbenzene. XPS, FTIR, and in situ DRIFTS analyses demonstrated that H₂ or O₂ pretreatment partially cleaved P–N bonds in the P₃N₅ framework, inducing structural reorganization and exposing the inner N₂P = O groups, thereby increasing the active site density. Among them, the H₂-pretreated PNO/Al₂O₃ catalyst (PNO/Al₂O₃-H) exhibited the highest N₂P = O content (a 74.2 % increase compared with PNO/Al₂O₃), which resulted in the highest catalytic activity (<em>X</em>_<em>EB</em>=58.5 %) under high-concentration ethylbenzene feed (12.2 vol%). This work demonstrates, for the first time, the application of atmosphere pretreatment to phosphorus-nitrogen catalysts and proposes a novel strategy for regulating the active site in dehydrogenation catalysis.</div></div>","PeriodicalId":243,"journal":{"name":"Applied Catalysis A: General","volume":"707 ","pages":"Article 120503"},"PeriodicalIF":4.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144852881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interlayer Sliding Induced Triferroic Coupling in 2D Bilayer NbSi2N4.","authors":"Yue Yang,Ying Zhao,Fanhan Kong,Qinxi Liu,Yan Su,Jijun Zhao,Xue Jiang","doi":"10.1021/acs.jpclett.5c02112","DOIUrl":"https://doi.org/10.1021/acs.jpclett.5c02112","url":null,"abstract":"Interlayer sliding symmetry breaking presents a powerful technique for achieving intrinsic multiferroic coupling among magnetism, ferroelectricity, and valley polarization, thereby establishing a new paradigm for the design of multifunctional devices. First-principles calculations unveil multiferroic coupling in 2D NbSi2N4. The monolayer exhibits a ferromagnetic ground state, where valley polarization is tuned by magnetic moment reversal. The energetically stable AB/BA-stacked bilayer hosts coexisting triferroic orders: antiferromagnetism, ferrovalley, and out-of-plane ferroelectricity. The interlayer-sliding-induced AB to BA transition enables non-volatile ferroelectric bistability via polarization reversal. The magneto-optic Kerr effect (MOKE) confirms magnetoelectric coupling between sliding ferroelectricity and antiferromagnetism. Valley polarization reversal is achieved by electric-field-driven polarization switching or magnetic-field-controlled magnetization direction flipping, inducing a significant stacking-dependent anomalous valley Hall effect (AVHE) and spin currents. This establishes NbSi2N4 as an ideal platform for novel non-volatile memory and spin-valleytronic devices.","PeriodicalId":62,"journal":{"name":"The Journal of Physical Chemistry Letters","volume":"104 1","pages":"8649-8656"},"PeriodicalIF":6.475,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144851029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Greenhouse Microclimate Management and Solar Energy - A Review of Possibilities for Botswana amid Climate Change Challenges","authors":"E.L. Thipe,&nbsp;J.E. Hoffmann,&nbsp;A.B. Sebitosi","doi":"10.1016/j.rser.2025.116145","DOIUrl":"10.1016/j.rser.2025.116145","url":null,"abstract":"<div><div>Botswana's climate is characterised by extreme conditions, exacerbated by climate change, which pose challenges for greenhouse horticulture and contribute to food insecurity. To mitigate these impacts, energy input in greenhouses is essential, and solar energy technologies present sustainable solutions for rural, resource-constrained farmers. This review examines the potential for managing greenhouse microclimates in Botswana using solar-based solutions, highlighting their strengths and limitations. It also identifies potential barriers to their broader adoption and recommends remedial measures to address these issues. Viable solutions include conventional photovoltaic modules and solar thermal storage systems, such as ground or rock-bed storage. Futuristic, semi-transparent organic solar cells show promise due to their in-house electricity generation and lower cooling loads, despite challenges such as lower efficiency and shorter lifespans. However, no single technology can effectively manage the microclimate in Botswana, highlighting the need for an integrated approach that combines various technologies. Barriers to adopting solar solutions include policy gaps, skills shortages, financial constraints, and inadequate research among local institutions. Recommendations to mitigate these barriers include enhancing policies and regulatory frameworks, developing innovative funding models, establishing a renewable energy research centre, and fostering collaborative research among local, regional, and international partners, as well as the development of responsive and robust curricula by local training institutions.</div></div>","PeriodicalId":418,"journal":{"name":"Renewable and Sustainable Energy Reviews","volume":"225 ","pages":"Article 116145"},"PeriodicalIF":16.3,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144842673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catalyst-Free Regioselective 1,6-Aza-Michael Addition of para-Quinone Methides with Tetrazoles in Water.","authors":"Yanan Li,Chenpei Yang,Jianan Sun,Kuiliang Li,Yifei Wang,Rui Zhu,Jiajing Tan,Peng Qian","doi":"10.1021/acs.joc.5c00689","DOIUrl":"https://doi.org/10.1021/acs.joc.5c00689","url":null,"abstract":"A facile catalyst-free regioselective 1,6-aza-Michael addition of para-quinone methides with tetrazoles was efficiently developed using water as a green solvent. This process exhibited broad substrate compatibility, including benzotriazole, pyrazole, and indazole, yielding the corresponding N-substituted azoles with excellent efficiency and regioselectivity. To demonstrate the practicality of this methodology, gram-scale reactions were successfully conducted. The possible mechanistic pathway is elucidated based on the preliminary results from control experiments as well as discrete fourier transform (DFT) calculations, which reveal that the solvent water plays a crucial role in facilitating the reaction by forming hydrogen bonds with the substrate, thereby enhancing the reaction progress.","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":"26 1","pages":""},"PeriodicalIF":4.354,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144825239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}