生理学报 Pub Date : 2025-06-25 DOI: 10.13294/j.aps.2025.0003

Xin-Yue Zheng, Ming Zhang, Kai-Qi Su, Zhi-Min Ding

引用次数: 0

[Development of a balloon sensor device for force-electrical coupling measurement of esophagus]. [用于食道力电耦合测量的球囊传感器装置的研制]。

生物医学工程学杂志 Pub Date : 2025-06-25 DOI: 10.7507/1001-5515.202404019

Peng Ran, Ying Zhong, Yingbing Lai, Lei Liu, Yanhang Zhu, Huantao Zhu

{"title":"[Development of a balloon sensor device for force-electrical coupling measurement of esophagus].","authors":"Peng Ran, Ying Zhong, Yingbing Lai, Lei Liu, Yanhang Zhu, Huantao Zhu","doi":"10.7507/1001-5515.202404019","DOIUrl":"https://doi.org/10.7507/1001-5515.202404019","url":null,"abstract":"<p><p>To address the challenges of capturing micro-strains in detecting esophageal motility disorders and the limitations of existing high-resolution manometry and functional intraluminal imaging probes in directly measuring esophageal tissue electrical impedance, this study proposes a novel flexible balloon sensor structure that integrates a piezoelectric film assembly with a distributed impedance electrode array. Using the electrical analysis module in the finite element analysis (FEA) software, simulations of the forward problem for esophageal impedance detection were conducted to optimize the excitation source parameters, and a physical prototype was fabricated. Under a relative excitation mode with a voltage sensitivity of 2.059%, the voltage output characteristics of the impedance electrode array were analyzed during linear changes in the balloon filling volume. Based on the performance variation of the piezoelectric film assembly, 80% was selected as the optimal filling volume. Force-electric coupling tests were conducted on the balloon sensor using a pressure testing platform, revealing that both the piezoelectric film assembly inside the balloon and the impedance electrodes outside the balloon exhibited significant load differentiation characteristics as the force application point shifted. In summary, this balloon sensor facilitates the localization of force application while simultaneously analyzing esophageal tissue properties, offering a novel diagnostic approach and objective tool for esophageal disease detection.</p>","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 3","pages":"610-619"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Brain-computer interface technology and its applications for patients with disorders of consciousness]. [脑机接口技术及其在意识障碍患者中的应用]。

生物医学工程学杂志 Pub Date : 2025-06-25 DOI: 10.7507/1001-5515.202410061

Jiahui Pan, Zhihang Zhang, Yuanlin Zhang, Fei Wang, Jun Xiao

引用次数: 0

[Modeling and finite element analysis of human trabecular meshwork outflow pathways]. [人体小梁网流出通道的建模与有限元分析]。

生物医学工程学杂志 Pub Date : 2025-06-25 DOI: 10.7507/1001-5515.202407037

Shiya Bao, Qing Sun, Si Chen, Xinyu Chen, Xiang Peng, Jing Zhang

{"title":"[Modeling and finite element analysis of human trabecular meshwork outflow pathways].","authors":"Shiya Bao, Qing Sun, Si Chen, Xinyu Chen, Xiang Peng, Jing Zhang","doi":"10.7507/1001-5515.202407037","DOIUrl":"https://doi.org/10.7507/1001-5515.202407037","url":null,"abstract":"<p><p>Glaucoma is the leading cause of irreversible blindness worldwide, with its primary risk factor arising from elevated intraocular pressure (IOP) due to an imbalance between aqueous humor production and outflow. This study aims to establish quantitative correlations among IOP, iris mechanical properties, channel microstructures, and aqueous humor dynamics through three-dimensional modeling and finite element analysis, overcoming the limitations of conventional experimental techniques in studying aqueous flow within the trabecular meshwork (TM) outflow pathway. A three-dimensional fluid-structure interaction (FSI) model incorporating the layered TM structure, Schlemm's canal (SC), iris, and other anterior segment tissues was developed based on human ocular anatomy. FSI simulations were performed to quantify the effects of IOP variations and iris Young's modulus on tissue morphology and aqueous humor dynamics parameters. The computational results demonstrated that axial iris deformation showed significant correlations with IOP and iris Young's modulus. Although elevated IOP exhibited minimal effects on hydrodynamic parameters in the anterior and posterior chambers, it markedly suppressed aqueous flow velocity in the TM region. Additionally, wall shear stress in SC and collector channels displayed high sensitivity to IOP variations. These findings reveal that the tissue mechanics-FSI mechanism modulates outflow resistance by regulating aqueous humor dynamics, offering valuable references for developing clinical therapies targeting IOP reduction in glaucoma management.</p>","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 3","pages":"585-591"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Performance evaluation of a wearable steady-state visual evoked potential based brain-computer interface in real-life scenario]. [基于视觉诱发电位的可穿戴稳态脑机接口在现实场景中的性能评估]。

生物医学工程学杂志 Pub Date : 2025-06-25 DOI: 10.7507/1001-5515.202310069

Xiaodong Li, Xiang Cao, Junlin Wang, Weijie Zhu, Yong Huang, Feng Wan, Yong Hu

{"title":"[Performance evaluation of a wearable steady-state visual evoked potential based brain-computer interface in real-life scenario].","authors":"Xiaodong Li, Xiang Cao, Junlin Wang, Weijie Zhu, Yong Huang, Feng Wan, Yong Hu","doi":"10.7507/1001-5515.202310069","DOIUrl":"https://doi.org/10.7507/1001-5515.202310069","url":null,"abstract":"<p><p>Brain-computer interface (BCI) has high application value in the field of healthcare. However, in practical clinical applications, convenience and system performance should be considered in the use of BCI. Wearable BCIs are generally with high convenience, but their performance in real-life scenario needs to be evaluated. This study proposed a wearable steady-state visual evoked potential (SSVEP)-based BCI system equipped with a small-sized electroencephalogram (EEG) collector and a high-performance training-free decoding algorithm. Ten healthy subjects participated in the test of BCI system under simplified experimental preparation. The results showed that the average classification accuracy of this BCI was 94.10% for 40 targets, and there was no significant difference compared to the dataset collected under the laboratory condition. The system achieved a maximum information transfer rate (ITR) of 115.25 bit/min with 8-channel signal and 98.49 bit/min with 4-channel signal, indicating that the 4-channel solution can be used as an option for the few-channel BCI. Overall, this wearable SSVEP-BCI can achieve good performance in real-life scenario, which helps to promote BCI technology in clinical practice.</p>","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 3","pages":"464-472"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Research on bimodal emotion recognition algorithm based on multi-branch bidirectional multi-scale time perception]. 基于多分支双向多尺度时间感知的双峰情绪识别算法研究

生物医学工程学杂志 Pub Date : 2025-06-25 DOI: 10.7507/1001-5515.202404047

Peiyun Xue, Sibin Wang, Jing Bai, Yan Qiang

{"title":"[Research on bimodal emotion recognition algorithm based on multi-branch bidirectional multi-scale time perception].","authors":"Peiyun Xue, Sibin Wang, Jing Bai, Yan Qiang","doi":"10.7507/1001-5515.202404047","DOIUrl":"https://doi.org/10.7507/1001-5515.202404047","url":null,"abstract":"<p><p>Emotion can reflect the psychological and physiological health of human beings, and the main expression of human emotion is voice and facial expression. How to extract and effectively integrate the two modes of emotion information is one of the main challenges faced by emotion recognition. In this paper, a multi-branch bidirectional multi-scale time perception model is proposed, which can detect the forward and reverse speech Mel-frequency spectrum coefficients in the time dimension. At the same time, the model uses causal convolution to obtain temporal correlation information between different scale features, and assigns attention maps to them according to the information, so as to obtain multi-scale fusion of speech emotion features. Secondly, this paper proposes a two-modal feature dynamic fusion algorithm, which combines the advantages of AlexNet and uses overlapping maximum pooling layers to obtain richer fusion features from different modal feature mosaic matrices. Experimental results show that the accuracy of the multi-branch bidirectional multi-scale time sensing dual-modal emotion recognition model proposed in this paper reaches 97.67% and 90.14% respectively on the two public audio and video emotion data sets, which is superior to other common methods, indicating that the proposed emotion recognition model can effectively capture emotion feature information and improve the accuracy of emotion recognition.</p>","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 3","pages":"528-536"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Research progress in central aortic pressure estimation algorithms]. [中央主动脉压估计算法研究进展]。

生物医学工程学杂志 Pub Date : 2025-06-25 DOI: 10.7507/1001-5515.202407014

Shuo Du, Shuran Zhou, Guanglei Wang, Haijun Zhu, Lisheng Xu

引用次数: 0

[Cellular differential impact of the Rap1 on atherosclerosis]. Rap1对动脉粥样硬化的细胞差异影响。

生理学报 Pub Date : 2025-06-25 DOI: 10.13294/j.aps.2025.0045

Shan-Shan Song, Hui-Ru Yang, Xiao-Li Yi, Jun Yu, Chuan-Ming Xu

引用次数: 0

[Biomechanical study of lumbar vertebra during gait cycle in adolescent idiopathic scoliosis]. [青少年特发性脊柱侧凸步态周期腰椎的生物力学研究]。

生物医学工程学杂志 Pub Date : 2025-06-25 DOI: 10.7507/1001-5515.202410010

Yunxin Wang, Ping Xu, Yingsong Wang, Yingliang Liu, Shisen Xu, Zhi Zhao, Hongfei Li, Xiaoming Chen

{"title":"[Biomechanical study of lumbar vertebra during gait cycle in adolescent idiopathic scoliosis].","authors":"Yunxin Wang, Ping Xu, Yingsong Wang, Yingliang Liu, Shisen Xu, Zhi Zhao, Hongfei Li, Xiaoming Chen","doi":"10.7507/1001-5515.202410010","DOIUrl":"https://doi.org/10.7507/1001-5515.202410010","url":null,"abstract":"<p><p>In order to investigate the mechanical response of lumbar vertebrae during gait cycle in adolescents with idiopathic scoliosis (AIS), the present study was based on computed tomography (CT) data of AIS patients to construct model of the left support phase (ML) and model of the right support phase (MR), respectively. Firstly, material properties, boundary conditions and load loading were set to simulate the lumbar vertebra-pelvis model. Then, the difference of stress and displacement in the lumbar spine between ML and MR was compared based on the stress and displacement cloud map. The results showed that in ML, the lumbar stress was mostly distributed on the convex side, while in MR, it was mostly distributed on the concave side. The stress of the two types of stress mainly gathered near the vertebral arch plate, and the stress of the vertebral arch plate was transmitted to the vertebral body through the pedicle with the progress of gait. The average stress of the intervertebral tissue in MR was greater than that in ML, and the difference of stress on the convex and convex side was greater. The displacement of lumbar vertebrae in ML decreased gradually from L1 to L5. The opposite is true in MR. In conclusion, this study can accurately quantify the stress on the lumbar spine during gait, and may provide guidance for brace design and clinical decision making.</p>","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 3","pages":"601-609"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the presence of toxic transformation products and microfibers on end-of-life RO membranes 揭示有毒转化产物和超细纤维在寿命结束的反渗透膜上的存在

IF 5.3 2区环境科学与生态学

Emerging Contaminants Pub Date : 2025-06-24 DOI: 10.1016/j.emcon.2025.100538

M.K. Akhil Nazim , Amitha Unnikrishnan , Anastasia Penkova , Charuvila T. Aravindakumar , Usha K. Aravind

{"title":"Unveiling the presence of toxic transformation products and microfibers on end-of-life RO membranes","authors":"M.K. Akhil Nazim , Amitha Unnikrishnan , Anastasia Penkova , Charuvila T. Aravindakumar , Usha K. Aravind","doi":"10.1016/j.emcon.2025.100538","DOIUrl":"10.1016/j.emcon.2025.100538","url":null,"abstract":"<div><div>Point-of-use (PoU) drinking water treatment systems using reverse osmosis (RO) are becoming increasingly popular. Over time, the membrane cartridges in these systems accumulate a concentrated layer of contaminants on their surfaces. This study focuses on analysing this fouling layer by performing autopsies on spent membrane cartridges from PoU units. Four used RO membranes were collected from rural and urban locations in Kerala, India. Two of these membranes treated groundwater in rural areas, while the other two were supplied by municipal water and groundwater in urban settings. The foulants desorbed from the membrane surfaces were analysed using a combination of spectroscopic, microscopic, and chromatographic methods. Non-target analysis (NTA) revealed the presence of micropollutants, including herbicides, personal care products, and pharmaceuticals. Toxic transformation products of diuron, namely 3,4-dichloroaniline and 3,4-dichlorophenyl-N-methylurea, were also detected. Raman spectroscopy identified polyethylene terephthalate (PET) and cotton microfibers, while inorganic foulants such as calcium, iron, silicon, and aluminium were also found. Infrared spectra confirmed that the membranes were composed of polypropylene, polysulfone, and polyurethane. Improper disposal of these end-of-life membranes risks reintroducing these contaminants into the environment.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100538"},"PeriodicalIF":5.3,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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