生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202406054

Yihao Du, Mengyu Sun, Jingjin Li, Xiaoran Wang, Tianfu Cao

{"title":"[Research on multi-scale convolutional neural network hand muscle strength prediction model improved based on convolutional attention module].","authors":"Yihao Du, Mengyu Sun, Jingjin Li, Xiaoran Wang, Tianfu Cao","doi":"10.7507/1001-5515.202406054","DOIUrl":"https://doi.org/10.7507/1001-5515.202406054","url":null,"abstract":"In order to realize the quantitative assessment of muscle strength in hand function rehabilitation and then formulate scientific and effective rehabilitation training strategies, this paper constructs a multi-scale convolutional neural network (MSCNN) - convolutional block attention module (CBAM) - bidirectional long short-term memory network (BiLSTM) muscle strength prediction model to fully explore the spatial and temporal features of the data and simultaneously suppress useless features, and finally achieve the improvement of the accuracy of the muscle strength prediction model. To verify the effectiveness of the model proposed in this paper, the model in this paper is compared with traditional models such as support vector machine (SVM), random forest (RF), convolutional neural network (CNN), CNN - squeeze excitation network (SENet), MSCNN-CBAM and MSCNN-BiLSTM, and the effect of muscle strength prediction by each model is investigated when the hand force application changes from 40% of the maximum voluntary contraction force (MVC) to 60% of the MVC. The research results show that as the hand force application increases, the effect of the muscle strength prediction model becomes worse. Then the ablation experiment is used to analyze the influence degree of each module on the muscle strength prediction result, and it is found that the CBAM module plays a key role in the model. Therefore, by using the model in this article, the accuracy of muscle strength prediction can be effectively improved, and the characteristics and laws of hand muscle activities can be deeply understood, providing assistance for further exploring the mechanism of hand functions .","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 1","pages":"90-95"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Study on lightweight plasma recognition algorithm based on depth image perception].

生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202404064

Hanwen Zhang, Yu Sun, Hao Jiang, Jintian Hu, Gangyin Luo, Dong Li, Weijuan Cao, Xiang Qiu

{"title":"[Study on lightweight plasma recognition algorithm based on depth image perception].","authors":"Hanwen Zhang, Yu Sun, Hao Jiang, Jintian Hu, Gangyin Luo, Dong Li, Weijuan Cao, Xiang Qiu","doi":"10.7507/1001-5515.202404064","DOIUrl":"https://doi.org/10.7507/1001-5515.202404064","url":null,"abstract":"In the clinical stage, suspected hemolytic plasma may cause hemolysis illness, manifesting as symptoms such as heart failure, severe anemia, etc. Applying a deep learning method to plasma images significantly improves recognition accuracy, so that this paper proposes a plasma quality detection model based on improved \"You Only Look Once\" 5th version (YOLOv5). Then the model presented in this paper and the evaluation system ‌were introduced‌ into the plasma datasets, and ‌the average accuracy of the final classification reached 98.7%‌. The results of this paper's experiment were obtained through the combination of several key algorithm modules including‌ omni-dimensional dynamic convolution, pooling with separable kernel attention, residual bi-fusion feature pyramid network, ‌and‌ re-parameterization convolution. The method of this paper‌ obtains the feature information of spatial mapping efficiently, and enhances the average recognition accuracy of plasma quality detection. This paper presents a high-efficiency detection method for plasma images, aiming to provide a practical approach to prevent hemolysis illnesses caused by external factors.","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 1","pages":"123-131"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Methods for enhancing image quality of soft tissue regions in synthetic CT based on cone-beam CT].

生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202407078

Ziwei Fu, Yechen Zhu, Zijian Zhang, Xin Gao

{"title":"[Methods for enhancing image quality of soft tissue regions in synthetic CT based on cone-beam CT].","authors":"Ziwei Fu, Yechen Zhu, Zijian Zhang, Xin Gao","doi":"10.7507/1001-5515.202407078","DOIUrl":"https://doi.org/10.7507/1001-5515.202407078","url":null,"abstract":"Synthetic CT (sCT) generated from CBCT has proven effective in artifact reduction and CT number correction, facilitating precise radiation dose calculation. However, the quality of different regions in sCT images is severely imbalanced, with soft tissue region exhibiting notably inferior quality compared to others. To address this imbalance, we proposed a Multi-Task Attention Network (MuTA-Net) based on VGG-16, specifically focusing the enhancement of image quality in soft tissue region of sCT. First, we introduced a multi-task learning strategy that divides the sCT generation task into three sub-tasks: global image generation, soft tissue region generation and bone region segmentation. This approach ensured the quality of overall sCT image while enhancing the network's focus on feature extraction and generation for soft tissues region. The result of bone region segmentation task guided the fusion of sub-tasks results. Then, we designed an attention module to further optimize feature extraction capabilities of the network. Finally, by employing a results fusion module, the results of three sub-tasks were integrated, generating a high-quality sCT image. Experimental results on head and neck CBCT demonstrated that the sCT images generated by the proposed MuTA-Net exhibited a 12.52% reduction in mean absolute error in soft tissue region, compared to the best performance among the three comparative methods, including ResNet, U-Net, and U-Net++. It can be seen that MuTA-Net is suitable for high-quality sCT image generation and has potential application value in the field of CBCT guided adaptive radiation therapy.","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 1","pages":"113-122"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological perspectives on emerging contaminants and gout or hyperuricemia 新出现的污染物与痛风或高尿酸血症的流行病学观点

IF 5.3 2区环境科学与生态学

Emerging Contaminants Pub Date : 2025-02-25 DOI: 10.1016/j.emcon.2025.100485

Weiwen Fu , Yangyi Guang , Zixing Zhang , Cheng Zhou , Xinyu Fang

引用次数: 0

[Controllability and predictability of riboflavin-ultraviolet A collagen cross-linking: advances in experimental techniques and theoretical research].

生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202402017

Xiaona Liu, Xiaona Li, Weiyi Chen

引用次数: 0

[Dynamic continuous emotion recognition method based on electroencephalography and eye movement signals].

生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202408013

Yangmeng Zou, Lilin Jie, Mingxun Wang, Yong Liu, Junhua Li

{"title":"[Dynamic continuous emotion recognition method based on electroencephalography and eye movement signals].","authors":"Yangmeng Zou, Lilin Jie, Mingxun Wang, Yong Liu, Junhua Li","doi":"10.7507/1001-5515.202408013","DOIUrl":"https://doi.org/10.7507/1001-5515.202408013","url":null,"abstract":"Existing emotion recognition research is typically limited to static laboratory settings and has not fully handle the changes in emotional states in dynamic scenarios. To address this problem, this paper proposes a method for dynamic continuous emotion recognition based on electroencephalography (EEG) and eye movement signals. Firstly, an experimental paradigm was designed to cover six dynamic emotion transition scenarios including happy to calm, calm to happy, sad to calm, calm to sad, nervous to calm, and calm to nervous. EEG and eye movement data were collected simultaneously from 20 subjects to fill the gap in current multimodal dynamic continuous emotion datasets. In the valence-arousal two-dimensional space, emotion ratings for stimulus videos were performed every five seconds on a scale of 1 to 9, and dynamic continuous emotion labels were normalized. Subsequently, frequency band features were extracted from the preprocessed EEG and eye movement data. A cascade feature fusion approach was used to effectively combine EEG and eye movement features, generating an information-rich multimodal feature vector. This feature vector was input into four regression models including support vector regression with radial basis function kernel, decision tree, random forest, and K-nearest neighbors, to develop the dynamic continuous emotion recognition model. The results showed that the proposed method achieved the lowest mean square error for valence and arousal across the six dynamic continuous emotions. This approach can accurately recognize various emotion transitions in dynamic situations, offering higher accuracy and robustness compared to using either EEG or eye movement signals alone, making it well-suited for practical applications.","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 1","pages":"32-41"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pancreas segmentation with multi-channel convolution and combined deep supervision].

生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202409019

Yue Yang, Yongxiong Wang, Chendong Qin

{"title":"[Pancreas segmentation with multi-channel convolution and combined deep supervision].","authors":"Yue Yang, Yongxiong Wang, Chendong Qin","doi":"10.7507/1001-5515.202409019","DOIUrl":"https://doi.org/10.7507/1001-5515.202409019","url":null,"abstract":"Due to its irregular shape and varying contour, pancreas segmentation is a recognized challenge in medical image segmentation. Convolutional neural network (CNN) and Transformer-based networks perform well but have limitations: CNN have constrained receptive fields, and Transformer underutilize image features. This work proposes an improved pancreas segmentation method by combining CNN and Transformer. Point-wise separable convolution was introduced in a stage-wise encoder to extract more features with fewer parameters. A densely connected ensemble decoder enabled multi-scale feature fusion, addressing the structural constraints of skip connections. Consistency terms and contrastive loss were integrated into deep supervision to ensure model accuracy. Extensive experiments on the Changhai and National Institute of Health (NIH) pancreas datasets achieved the highest Dice similarity coefficient (DSC) values of 76.32% and 86.78%, with superiority in other metrics. Ablation studies validated each component's contributions to performance and parameter reduction. Results demonstrate that the proposed loss function smooths training and optimizes performance. Overall, the method outperforms other advanced methods, enhances pancreas segmentation performance, supports physician diagnosis, and provides a reliable reference for future research.","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 1","pages":"140-147"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Research on arrhythmia classification algorithm based on adaptive multi-feature fusion network].

生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202406069

Mengmeng Huang, Mingfeng Jiang, Yang Li, Xiaoyu He, Zefeng Wang, Yongquan Wu, Wei Ke

{"title":"[Research on arrhythmia classification algorithm based on adaptive multi-feature fusion network].","authors":"Mengmeng Huang, Mingfeng Jiang, Yang Li, Xiaoyu He, Zefeng Wang, Yongquan Wu, Wei Ke","doi":"10.7507/1001-5515.202406069","DOIUrl":"https://doi.org/10.7507/1001-5515.202406069","url":null,"abstract":"Deep learning method can be used to automatically analyze electrocardiogram (ECG) data and rapidly implement arrhythmia classification, which provides significant clinical value for the early screening of arrhythmias. How to select arrhythmia features effectively under limited abnormal sample supervision is an urgent issue to address. This paper proposed an arrhythmia classification algorithm based on an adaptive multi-feature fusion network. The algorithm extracted RR interval features from ECG signals, employed one-dimensional convolutional neural network (1D-CNN) to extract time-domain deep features, employed Mel frequency cepstral coefficients (MFCC) and two-dimensional convolutional neural network (2D-CNN) to extract frequency-domain deep features. The features were fused using adaptive weighting strategy for arrhythmia classification. The paper used the arrhythmia database jointly developed by the Massachusetts Institute of Technology and Beth Israel Hospital (MIT-BIH) and evaluated the algorithm under the inter-patient paradigm. Experimental results demonstrated that the proposed algorithm achieved an average precision of 75.2%, an average recall of 70.1% and an average F 1-score of 71.3%, demonstrating high classification accuracy and being able to provide algorithmic support for arrhythmia classification in wearable devices.","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 1","pages":"49-56"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Research progress on point-of-care testing of blood biochemical indexes based on microfluidic technology].

生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202406061

Huaqing Zhang, Canjie Hu, Pengjia Qi, Zhanlu Yu, Wei Chen, Jijun Tong

{"title":"[Research progress on point-of-care testing of blood biochemical indexes based on microfluidic technology].","authors":"Huaqing Zhang, Canjie Hu, Pengjia Qi, Zhanlu Yu, Wei Chen, Jijun Tong","doi":"10.7507/1001-5515.202406061","DOIUrl":"https://doi.org/10.7507/1001-5515.202406061","url":null,"abstract":"Blood biochemical indicators are an important basis for the diagnosis and treatment by doctors. The performance of related instruments, the qualification of operators, the storage method and time of blood samples and other factors will affect the accuracy of test results. However, it is difficult to meet the clinical needs of rapid detection and early screening of diseases with currently available methods. Point-of-care testing (POCT) is a new diagnostic technology with the characteristics of instant, portability, accuracy and efficiency. Microfluidic chips can provide an ideal experimental reaction platform for POCT. This paper summarizes the existing detection methods for common biochemical indicators such as blood glucose, lactic acid, uric acid, dopamine and cholesterol, and focuses on the application status of POCT based on microfluidic technology in blood biochemistry. It also summarizes the advantages and challenges of existing methods and prospects for development. The purpose of this paper is to provide relevant basis for breaking through the technical barriers of microfluidic and POCT product development in China.","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 1","pages":"205-211"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Experimental study on injection completion rate and performance for needle-free insulin injection].

生物医学工程学杂志 Pub Date : 2025-02-25 DOI: 10.7507/1001-5515.202406035

Yang Zhu, Can Kang, Wei Cai, Chao Huang

{"title":"[Experimental study on injection completion rate and performance for needle-free insulin injection].","authors":"Yang Zhu, Can Kang, Wei Cai, Chao Huang","doi":"10.7507/1001-5515.202406035","DOIUrl":"https://doi.org/10.7507/1001-5515.202406035","url":null,"abstract":"As a relatively novel technique for drug delivery, the needle-free injection technique is characterized by transporting the drug liquid to the designated subcutaneous position through a high-speed micro-jet. Although this technique has been applied in many fields, the research on its drug dispersion mechanism and injection performance is insufficient. The presented study aims to identify critical parameters during the injection process and describe their influence on the injection effect. The injection completion rate and performance of a needle-free injector under various operating conditions were compared based on mouse experiments. The results show that the nozzle diameter imposes a more significant influence on jet characteristics than other injection parameters. Moreover, the injection completion rate increases with the nozzle diameter. The nozzle diameters of 0.14 mm and 0.25 mm correspond to injection completion rates of 89.7% and 95.8%, respectively. Furthermore, by analyzing the rate of blood glucose change in the tested mice, it is found that insulin administration through the needle-free injection can achieve a drug effect duration longer than 120 min, which is better than that obtained using conventional needle-syringe technique. In summary, the obtained conclusions can provide an important reference for the optimal design and extending application of the air-powered needle-free injector.","PeriodicalId":39324,"journal":{"name":"生物医学工程学杂志","volume":"42 1","pages":"181-188"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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