国际机械系统动力学学报(英文)Pub Date : 2026-10-08Epub Date: 2026-07-07DOI: 10.1002/msd2.70079
Milad Shabani Yousefabad, Behzad Totakhaneh Bonab, Morteza Homayoun Sadeghi, Mir Mohammad Ettefagh, Mohammad Reza Chalak Qazani
{"title":"Detecting Loosening of Bolt-Flanged Pipe Using Smoothed Pseudo Wigner–Ville Distribution: Digital Twin-Based Approach Using Convolution Neural Networks","authors":"Milad Shabani Yousefabad, Behzad Totakhaneh Bonab, Morteza Homayoun Sadeghi, Mir Mohammad Ettefagh, Mohammad Reza Chalak Qazani","doi":"10.1002/msd2.70079","DOIUrl":"https://doi.org/10.1002/msd2.70079","url":null,"abstract":"<p>In this paper, an integrated digital twin-based fault-diagnosis framework is proposed to detect bolt loosening in flanged pipe connections. The approach combines finite element-based numerical modeling, experimental modal analysis, and advanced signal processing-assisted deep learning to achieve reliable loosening detection under operational excitations. First, a finite element model of the bolted flange pipe is developed and updated using experimentally identified natural frequencies to establish a validated digital twin. The dynamic responses of healthy and loosened bolt conditions are then simulated and experimentally measured. To extract fault-sensitive features, the vibration signals are decomposed using a Haar filter bank, followed by transformation into the time–frequency domain using the Smoothed Pseudo Wigner– Ville distribution (SPWVD). The resulting time–frequency representations are subsequently used to train a convolutional neural network (CNN). A key contribution of this study lies in the hybrid digital twin learning strategy, in which CNN training is performed using numerical data and healthy experimental data. At the same time, fault classification is conducted under experimental loosening conditions. The results demonstrate that the proposed framework effectively captures bolt loosening signatures and provides a practical, physics-consistent solution for condition monitoring of bolted flange connections.</p>","PeriodicalId":60486,"journal":{"name":"国际机械系统动力学学报(英文)","volume":"6 3","pages":"407-424"},"PeriodicalIF":3.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/msd2.70079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149125807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
国际机械系统动力学学报(英文)Pub Date : 2026-10-08Epub Date: 2026-06-09DOI: 10.1002/msd2.70075
Mario Spirto, Pierangelo Malfi, Armando Nicolella, Francesco Melluso, Chiara Cosenza, Sergio Savino, Vincenzo Niola
{"title":"Fault Detection of Electric Motors via Symmetrized Dot Pattern-Based Features","authors":"Mario Spirto, Pierangelo Malfi, Armando Nicolella, Francesco Melluso, Chiara Cosenza, Sergio Savino, Vincenzo Niola","doi":"10.1002/msd2.70075","DOIUrl":"https://doi.org/10.1002/msd2.70075","url":null,"abstract":"<p>This study proposes a novel symmetrized dot pattern (SDP) approach using designed SDP-based features, extracted from transformed vibration signals, for fault detection. These features describe the compactness, inclination, and shape of the “snowflake” diagram distributions. They were employed as inputs to a feedforward neural network for the automatic fault detection process. The effectiveness of the new technique was demonstrated on two experimental datasets of electric motors. The use of electric motors dataset is an application of the new technique that includes different fault types, fault severity levels, and operating conditions. The proposed method was also compared with the conventional one consisting of fault detection using the SDP derived images and convolutional neural network. The results demonstrate that the proposed SDP-features and feedforward neural network outperforms both the SDP, images, and convolutional neural network method in terms of classification accuracy and low false positive rates. Moreover, the novel method does not necessitate imaging, achieves higher accuracy and a lower false-positive rate than the conventional method. The new approach demonstrates a reduction in complexity and an enhancement in efficiency in comparison with the conventional one, and an automatic fault detection process.</p>","PeriodicalId":60486,"journal":{"name":"国际机械系统动力学学报(英文)","volume":"6 3","pages":"445-459"},"PeriodicalIF":3.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/msd2.70075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149125813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
国际机械系统动力学学报(英文)Pub Date : 2026-10-08Epub Date: 2026-05-06DOI: 10.1002/msd2.70072
Mohammad Alabdullah, Khaled Alhazza
{"title":"Vibration Attenuation of Cantilever Beam Using Electromagnetic Delayed Feedback","authors":"Mohammad Alabdullah, Khaled Alhazza","doi":"10.1002/msd2.70072","DOIUrl":"https://doi.org/10.1002/msd2.70072","url":null,"abstract":"<p>This study presents a combined analytical and numerical investigation of a single-input single-output delayed feedback controller designed to suppress vibrations in a cantilever beam actuated by an electromagnet positioned beneath its free end. An analytical model was developed using the linearized equation of motion for a transversely excited cantilever beam, incorporating an electromagnetic actuation force term, and solved numerically. In parallel, a finite element model coupling solid mechanics and magnetic fields was implemented in COMSOL Multiphysics. To capture the nonlinear variation of the magnetic force with beam deflection, a moving mesh technique was employed. Continuous delayed feedback was applied within the finite element framework using built-in operators that access solutions from previous time steps. Stability regions and normalized damping values were obtained from both models and compared to assess the validity of the analytical formulation. The results show that optimal controller gains and delays can be identified, with the delay remaining nearly invariant while the optimal gain exhibited sensitivity to the initial vibration amplitude. Unlike conventional feedback control, the electromagnet-based delayed feedback controller demonstrated amplitude-dependent behavior but achieved significant suppression of the first vibration mode.</p>","PeriodicalId":60486,"journal":{"name":"国际机械系统动力学学报(英文)","volume":"6 3","pages":"477-488"},"PeriodicalIF":3.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/msd2.70072","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149125769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
国际机械系统动力学学报(英文)Pub Date : 2026-10-08Epub Date: 2026-06-21DOI: 10.1002/msd2.70077
Min Wei, Yuchen He, Xiaoting Rui, Yixin Liu, Lilin Gu
{"title":"Design, Analysis, and Experimental Validation of a Variable-Gap Magnetorheological Damper for Seat Suspension","authors":"Min Wei, Yuchen He, Xiaoting Rui, Yixin Liu, Lilin Gu","doi":"10.1002/msd2.70077","DOIUrl":"https://doi.org/10.1002/msd2.70077","url":null,"abstract":"<p>To address the dual challenges of routine driving vibration and impact loads in vehicle seat suspensions, a novel variable-gap magnetorheological damper (VGMRD) is proposed. By combining a tapered piston with a conformal variable-diameter cylinder, stroke-dependent, dual-mode damping characteristics are achieved without the need for complex control valves. A theoretical model incorporating the stroke-dependent gap flow dynamics is established, and a finite element analysis of the internal magnetic field distribution is conducted. Numerical results indicate that the magnetic flux lines are concentrated by the converging geometry of the buffer zone, increasing the magnetic flux density by 17.4% without additional power input. Experimental validations utilizing a servo-hydraulic testing system are performed, and the experimental results show good agreement with the theoretical predictions. Specifically, the damping force remains stable within the damping zone. As the piston enters the buffer zone, the damping force increases significantly with displacement. Through the passive self-reinforcement mechanism, the peak damping force is effectively elevated from 2240 N in the damping zone to a maximum of 4296 N. These findings demonstrate the reliability of the proposed VGMRD in preventing mechanical “bottoming-out” while maintaining routine ride comfort.</p>","PeriodicalId":60486,"journal":{"name":"国际机械系统动力学学报(英文)","volume":"6 3","pages":"460-476"},"PeriodicalIF":3.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/msd2.70077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149125793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Insight into the sunlight-mediated photodegradation of active pharmaceuticals using ZnO-doped TiO2/Carbon nanocomposite derived from leather waste","authors":"Ravichandran Sushmitha, Palanisamy Thanikaivelan","doi":"10.1186/s42825-026-00270-9","DOIUrl":"10.1186/s42825-026-00270-9","url":null,"abstract":"<div><p>Treatment of pharmaceutical wastewater is gaining importance due to health risks. In this study, carbon sourced from vegetable-tanned leather waste was utilized to develop an effective photocatalyst. ZnO incorporated TiO<sub>2</sub>/carbon nanocomposites were synthesized via the sol–gel route by systematically changing the TiO<sub>2</sub>:ZnO mass ratio. The nanocomposites exhibited a reduction in band gap energy values and particle size as ZnO content increased. The photocatalytic performance of the synthesized materials was tested for degrading sulfasalazine (SUZ) and losartan potassium (LP) under visible light and sunlight conditions. The ZnO@TiO<sub>2</sub>/carbon (with a 1:0.075 mass ratio of TiO<sub>2</sub>:ZnO) nanocomposite with a band gap energy of 3.23 eV demonstrated maximum degradation efficiencies of 97% and 96% for SUZ and LP, respectively, under sunlight illumination within 120 min. The photocatalytic degradation of SUZ was studied using radical scavengers and EPR spin-trap experiments. The findings indicate that superoxide (O<sub>2</sub><sup>⋅−</sup>), holes from valence band (h<sub>vb</sub><sup>+</sup>) and adsorbed hydroxyl radicals (<sup>⋅</sup>OH<sub>ads</sub>) are the primary reactive species involved in the degradation of SUZ. Catalyst reuse was demonstrated up to three cycles. The photocatalytic performance was further evaluated in a synthetic wastewater matrix containing representative inorganic ions and natural organic matter, where the CTZ5 nanocomposite maintained appreciable degradation efficiency. ESI/MS based mechanistic studies identified 4-nitro-<i>N</i>-(2-pyridinyl)benzenesulfonamide and sulfapyridine as key intermediates. These findings highlight the nanocomposite’s strong potential for pharmaceutical wastewater treatment, thus contributing to environmental sustainability.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s42825-026-00270-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149132414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Can Li, Yuanhang Zhang, Wan Li, Li Wang, Jun Xiang, Haojun Fan, Hongmei Jiang, Lijuan Sun, Jinsong Tang
{"title":"Bio-hydrophilic chain extenders with amphiphilic character for waterborne polyurethane derived from castor oil/tea seed oil: separation, synthesis, and application","authors":"Can Li, Yuanhang Zhang, Wan Li, Li Wang, Jun Xiang, Haojun Fan, Hongmei Jiang, Lijuan Sun, Jinsong Tang","doi":"10.1186/s42825-026-00263-8","DOIUrl":"10.1186/s42825-026-00263-8","url":null,"abstract":"<div><p>Unsaturated vegetable fatty acids, as a renewable resource, are abundantly present in vegetable oils, exhibiting significant potential for the synthesis of bio-polyols and bio-based polyurethanes (PUs). Herein, castor oil (CO) and tea seed oil (TSO) were selected as feedstocks to fabricate bio-based hydrophilic chain extenders (HCEs) for water-based polyurethane (WPU). Firstly, the raw oils were treated through a three-step process involving saponification, acidification and urea inclusion purification, yielding unsaturated ricinoleic acid (RA) and oleic acid (OA) with high purities of 93.99% and 92.72%, respectively. Subsequently, an efficient thiol-ene click reaction was carried out to prepare amphiphilic ricinoleic acid-based chain extender (RACE) and amphiphilic oleic acid-based chain extender (OACE) under ambient conditions (1 h, room temperature) with relatively lower molecular weight (<i>M</i><sub>w</sub>) and accurate functionality (<i>f</i><sub>− OH</sub><i>= 2</i>). The activation energies for the reactions of RACE/OACE and dimethylolpropionic acid (DMPA) with isophorone diisocyanate (IPDI) were evaluated via non-isothermal DSC kinetic analysis (Kissinger method and Ozawa method), and the apparent activation energy (<i>Ea</i> from Kissinger/<i>Eo</i> from Ozawa) values were found to be 76.66/78.88 kJ·mol<sup>−</sup>¹ for RACE and 74.58/76.91 kJ·mol<sup>−</sup>¹ for OACE, respectively, which were slightly higher than that of DMPA (Ea/Eo = 73.01/75.32 kJ·mol<sup>−</sup>¹). Application of these bio-HCEs for preparing WPU revealed that the particle size and absolute zeta potential of emulsion with more than 0.0248 mol bio-HCEs were equivalent to those of the emulsion with 0.0192 mol DMPA, and the resultant WPU films showed enhanced broken elongation, increased water contact angles, and reduced water absorption ratio. Collectively, the significance of this work resides in providing a feasible and potentially universal strategy for fabricating bio-HCEs from natural unsaturated oils and offering a sustainable alternative for the advancement of WPU.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s42825-026-00263-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149132412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kai Wang, Xin Luo, Weidong Zhao, Yan Bao, Xiaoyan Pang, Jian Sun
{"title":"Ionic liquids promote extraction of collagen from skins/leather and application of collagen-based materials","authors":"Kai Wang, Xin Luo, Weidong Zhao, Yan Bao, Xiaoyan Pang, Jian Sun","doi":"10.1186/s42825-026-00259-4","DOIUrl":"10.1186/s42825-026-00259-4","url":null,"abstract":"<div><p>Collagen is the key structural component of skins and leather. Currently, the commonly used methods for collagen extraction are acid treatment, alkaline treatment, or enzymatic hydrolysis. However, these approaches often compromise the native molecular structure and generate significant environmental burdens. As one of the green, and highly efficient extraction strategies, ionic liquids (ILs) technology has emerged as a promising direction. This work first outlines the advantages of the ILs extraction method over other extraction techniques. The IL extraction method can enhance collagen yield, and its extraction process is more environmentally friendly and economical. Subsequently, it reviews recent advances in collagen extraction from skins and leather using ILs, emphasizing their role in enhancing collagen yield. The work summarizes the mechanism whereby ILs disrupt hydrogen bonds and ionic bonds stabilizing collagen molecular structures, thereby forming reversible new interactions to facilitate extraction. It was found that ILs have significant advantages in the application of collagen-based materials. In addition to improving the extraction efficiency of collagen, ILs can also promote the functionalization modification of collagen. It can not only regulate the microstructure and mechanical properties of collagen, but also give collagen antibacterial, conductive and other functions. Meanwhile, due to the low volatility, low toxicity and recyclability of ILs, the cost and environmental risks are greatly reduced. Particular attention is given to practical applications in drug delivery systems, tissue engineering, flexible sensors, and leather industry, underlining the broad technological relevance of this approach. Finally, we identify current limitations and outline future research directions. By consolidating the latest findings, this review aims to accelerate broader adoption of IL technologies, fostering greener, more sustainable trajectories for collagen.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s42825-026-00259-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149132386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Animal collagen as a source of antihypertensive bioactive peptides: production technologies, structural characteristics, and molecular mechanisms","authors":"Phanthipha Laosam, Rayudika Aprilia Patindra Purba, Sasikan Katemala, Saranya Suwanangul, Chakkapat Aenglong, Nattapol Pongsamai, Yong Yue, Jukkrapong Pinyo, Papungkorn Sangsawad","doi":"10.1186/s42825-026-00265-6","DOIUrl":"10.1186/s42825-026-00265-6","url":null,"abstract":"<div><p>Hypertension affects approximately 1.4 billion adults globally, yet nearly 80% of hypertensive individuals remain inadequately controlled, underscoring the urgent need for safe, food-based interventions. Collagen-derived bioactive peptides from animal sources represent promising functional food ingredients for blood pressure management through controlled enzymatic hydrolysis. This review integrates evidence from source characteristics through clinical validation. A critical synthesis of 47 characterized peptides across bovine, porcine, poultry, and marine sources suggests that enzymatic processing parameters, rather than source origin per se, are key determinants of peptide bioactivity, with hydrolysis conditions critically influencing peptide size distribution, sequence diversity, and ACE inhibitory potency. Multiple complementary mechanisms extending beyond angiotensin-converting enzyme inhibition—including antioxidant activity, endothelial function restoration, and renin-angiotensin system modulation—operate synergistically, contributing to blood pressure reduction. Clinical evidence from randomized controlled trials and meta-analyses confirms significant antihypertensive efficacy in humans with favourable safety profiles. Quality standardization encompassing structure-activity characterization and functional biomarkers remains a key bottleneck for functional food applications. This review bridges agricultural animal production and food science by establishing a comprehensive framework linking collagen source selection, processing technology, peptide structure, and clinical outcomes—providing actionable guidance for developing evidence-based antihypertensive functional foods.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s42825-026-00265-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149132413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国医学科学院学报Pub Date : 2026-09-30DOI: 10.3881/j.issn.1000-503X.17189
Yu-Xin Yan, Nan Zheng, Yang Li, Jun Tang, Yi-Fei Pang, Xin-Yi Ding, Xiao-Mei Ren
{"title":"[Disease Burden of Non-alcoholic Steatohepatitis-Associated Hepatocellular Carcinoma in China,the Globe,and Regions with Different Socio-Demographic Indices,1990-2021].","authors":"Yu-Xin Yan, Nan Zheng, Yang Li, Jun Tang, Yi-Fei Pang, Xin-Yi Ding, Xiao-Mei Ren","doi":"10.3881/j.issn.1000-503X.17189","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.17189","url":null,"abstract":"<p><p>Objective To analyze the disease burden and trends of non-alcoholic steatohepatitis-associated hepatocellular carcinoma (NASH-HCC) in China,the globe,and regions with varying socio-demographic indices (SDI) from 1990 to 2021,thus providing theoretical support for the prevention and control of NASH-HCC. Methods Using the Global Burden of Disease Study 2021 database,we assessed the age-standardized incidence rate,prevalence rate,mortality rate,disability-adjusted life years (DALYs),and other disease burden metrics for NASH-HCC,along with their trends.Decomposition analysis and frontier analysis were performed to evaluate influencing factors and regional disparities. Results From 1990 to 2021,the age-standardized incidence rate of NASH-HCC in the globe increased from 0.36 per 100 000 to 0.49 per 100 000,while that in China rose from 0.48 per 100 000 to 0.54 per 100 000.All burden indicators in China showed lower growth rates than the global average.The burden increased most significantly in high-SDI regions and decreased in low-SDI regions.Decomposition analysis revealed that population aging was the primary driver of burden changes in China,while epidemiological shifts were the main factor contributing to global prevalence changes.Frontier analysis indicated that China ranked in the middle globally in terms of the effective gap between its age-standardized mortality rate,age-standardized DALY rate,and the theoretically optimal prevention and control level. Conclusions The global disease burden of NASH-HCC keeps rising,with the most significant increase occurring in high-SDI regions.There are substantial disparities in prevention and control capabilities across regions with different SDI.Comprehensive public health policies,targeted interventions,and effective treatment strategies must be developed to further enhance prevention and control efficacy.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国医疗器械杂志Pub Date : 2026-09-30DOI: 10.12455/j.issn.1671-7104.260102
Longfu Tian, Jiping Wang, Guodong Yang, Zhiyong Yang, Xin Li
{"title":"[Application and Future Prospects of Magnetic Resonance-Guided Adaptive Radiotherapy in Lung Cancer Treatment].","authors":"Longfu Tian, Jiping Wang, Guodong Yang, Zhiyong Yang, Xin Li","doi":"10.12455/j.issn.1671-7104.260102","DOIUrl":"10.12455/j.issn.1671-7104.260102","url":null,"abstract":"<p><p>Magnetic resonance-guided adaptive radiotherapy (MRgART) represents a significant advancement in the field of lung cancer treatment, integrating real-time magnetic resonance imaging (MRI) for monitoring and dynamic dose adjustment. This review provides a comprehensive analysis of the fundamental principles, technological advancements, clinical applications, and prospective developments of MRgART. It emphasizes the core benefits of MRgART in lung cancer therapy. Precise delineation of tumor boundaries is achieved based on the high soft-tissue resolution of MRI. This precision, coupled with online adaptive plan modifications, effectively addresses challenges posed by respiratory motion and tumor volume fluctuations, thereby improving target dose coverage and minimizing toxicity to surrounding healthy tissues.</p>","PeriodicalId":52535,"journal":{"name":"中国医疗器械杂志","volume":"50 5","pages":"498-504"},"PeriodicalIF":0.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}