理学最新文献_第9页

Deep learning enhanced light sheet fluorescence microscopy for in vivo 4D imaging of zebrafish heart beating

Light-Science & Applications Pub Date : 2025-02-25 DOI: 10.1038/s41377-024-01710-z

Meng Zhang, Renjian Li, Songnian Fu, Sunil Kumar, James Mcginty, Yuwen Qin, Lingling Chen

{"title":"Deep learning enhanced light sheet fluorescence microscopy for in vivo 4D imaging of zebrafish heart beating","authors":"Meng Zhang, Renjian Li, Songnian Fu, Sunil Kumar, James Mcginty, Yuwen Qin, Lingling Chen","doi":"10.1038/s41377-024-01710-z","DOIUrl":"https://doi.org/10.1038/s41377-024-01710-z","url":null,"abstract":"Time-resolved volumetric fluorescence imaging over an extended duration with high spatial/temporal resolution is a key driving force in biomedical research for investigating spatial-temporal dynamics at organism-level systems, yet it remains a major challenge due to the trade-off among imaging speed, light exposure, illumination power, and image quality. Here, we present a deep-learning enhanced light sheet fluorescence microscopy (LSFM) approach that addresses the restoration of rapid volumetric time-lapse imaging with less than 0.03% light exposure and 3.3% acquisition time compared to a typical standard acquisition. We demonstrate that the convolutional neural network (CNN)-transformer network developed here, namely U-net integrated transformer (UI-Trans), successfully achieves the mitigation of complex noise-scattering-coupled degradation and outperforms state-of-the-art deep learning networks, due to its capability of faithfully learning fine details while comprehending complex global features. With the fast generation of appropriate training data via flexible switching between confocal line-scanning LSFM (LS-LSFM) and conventional LSFM, this method achieves a three- to five-fold signal-to-noise ratio (SNR) improvement and ~1.8 times contrast improvement in ex vivo zebrafish heart imaging and long-term in vivo 4D (3D morphology + time) imaging of heartbeat dynamics at different developmental stages with ultra-economical acquisitions in terms of light dosage and acquisition time.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Robust low threshold full-color upconversion lasing in rare-earth activated nanocrystal-in-glass microcavity

Light-Science & Applications Pub Date : 2025-02-25 DOI: 10.1038/s41377-025-01765-6

Zhigang Gao, Lugui Cui, Yushi Chu, Luyue Niu, Lehan Wang, Rui Zhao, Yulong Yang, Xiaofeng Liu, Jing Ren, Guoping Dong

引用次数: 0

An achromatic metasurface waveguide for augmented reality displays

Light-Science & Applications Pub Date : 2025-02-25 DOI: 10.1038/s41377-025-01761-w

Zhongtao Tian, Xiuling Zhu, Philip A. Surman, Zhidong Chen, Xiao Wei Sun

{"title":"An achromatic metasurface waveguide for augmented reality displays","authors":"Zhongtao Tian, Xiuling Zhu, Philip A. Surman, Zhidong Chen, Xiao Wei Sun","doi":"10.1038/s41377-025-01761-w","DOIUrl":"https://doi.org/10.1038/s41377-025-01761-w","url":null,"abstract":"Augmented reality (AR) displays are emerging as the next generation of interactive platform, providing deeper human-digital interactions and immersive experiences beyond traditional flat-panel displays. Diffractive waveguide is a promising optical combiner technology for AR owing to its potential for the slimmest geometry and lightest weight. However, severe chromatic aberration of diffractive coupler has constrained widespread adoption of diffractive waveguide. Wavelength-dependent light deflection, caused by dispersion in both in-coupling and out-coupling processes, results in limited full-color field of view (FOV) and nonuniform optical responses in color and angular domains. Here we introduce an innovative full-color AR system that overcomes this long-standing challenge of chromatic aberration using a combination of inverse-designed metasurface couplers and a high refractive index waveguide. The optimized metasurface couplers demonstrate true achromatic behavior across the maximum FOV supported by the waveguide (exceeding 45°). Our AR prototype based on the designed metasurface waveguide, exhibits superior color accuracy and uniformity. This unique achromatic metasurface waveguide technology is expected to advance the development of visually compelling experience in compact AR display systems.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in ultrafast photonics: confluence of nonlinear optics and intelligent strategies

Light-Science & Applications Pub Date : 2025-02-25 DOI: 10.1038/s41377-024-01732-7

Qing Wu, Liuxing Peng, Zhihao Huang, Xiaolei Liu, Meng Luo, Danheng Gao, Haoran Meng

引用次数: 0

Progress on intelligent metasurfaces for signal relay, transmitter, and processor

Light-Science & Applications Pub Date : 2025-02-25 DOI: 10.1038/s41377-024-01729-2

Chao Qian, Longwei Tian, Hongsheng Chen

{"title":"Progress on intelligent metasurfaces for signal relay, transmitter, and processor","authors":"Chao Qian, Longwei Tian, Hongsheng Chen","doi":"10.1038/s41377-024-01729-2","DOIUrl":"https://doi.org/10.1038/s41377-024-01729-2","url":null,"abstract":"Pursuing higher data rate with limited spectral resources is a longstanding topic that has triggered the fast growth of modern wireless communication techniques. However, the massive deployment of active nodes to compensate for propagation loss necessitates high hardware expenditure, energy consumption, and maintenance cost, as well as complicated network interference issues. Intelligent metasurfaces, composed of a number of subwavelength passive or active meta-atoms, have recently found to be a new paradigm to actively reshape wireless communication environment in a green way, distinct from conventional works that passively adapt to the surrounding. In this review, we offer a unified perspective on how intelligent metasurfaces can facilitate wireless communication in three manners: signal relay, signal transmitter, and signal processor. We start by the basic modeling of wireless channel and the evolution of metasurfaces from passive, active to intelligent metasurfaces. Integrated with various deep learning algorithms, intelligent metasurfaces adapt to cater for the ever-changing environments without human intervention. Then, we overview specific experimental advancements using intelligent metasurfaces. We conclude by identifying key issues in the practical implementations of intelligent metasurfaces, and surveying new directions, such as gain metasurfaces and knowledge migration.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microcavity optomechanical magnetometry with picotesla-sensitivity

Light-Science & Applications Pub Date : 2025-02-20 DOI: 10.1038/s41377-025-01767-4

Zhaoyu Cai, Chengying Bao

引用次数: 0

Innovations in bulk photovoltaics: design strategies for boosted photocurrent

Light-Science & Applications Pub Date : 2025-02-20 DOI: 10.1038/s41377-025-01764-7

Akhil Sreevalsan, Hyosung Choi

引用次数: 0

Dispersive optical activity for spectro-polarimetric imaging

Light-Science & Applications Pub Date : 2025-02-20 DOI: 10.1038/s41377-025-01766-5

Zhijie Cao, Siwei Sun, Jingxuan Wei, Yong Liu

引用次数: 0

“QuanTour” illuminates Europe with single photons: celebrating the International Year of Quantum Science and Technology 2025 "量子之旅 "用单光子照亮欧洲：庆祝 2025 国际量子科技年

Light-Science & Applications Pub Date : 2025-02-17 DOI: 10.1038/s41377-025-01745-w

Fei Ding

引用次数: 0

Compact and reciprocal probe-signal-integrated rotational Doppler velocimetry with fiber-sculpted light

Light-Science & Applications Pub Date : 2025-02-17 DOI: 10.1038/s41377-025-01747-8

Zhenyu Wan, Ziyi Tang, Xi Zhang, Miles J. Padgett, Jian Wang

{"title":"Compact and reciprocal probe-signal-integrated rotational Doppler velocimetry with fiber-sculpted light","authors":"Zhenyu Wan, Ziyi Tang, Xi Zhang, Miles J. Padgett, Jian Wang","doi":"10.1038/s41377-025-01747-8","DOIUrl":"https://doi.org/10.1038/s41377-025-01747-8","url":null,"abstract":"In recent years, with the clarification of the mechanism of the rotational Doppler effect (RDE), there has attracted extensive attention to its development of applications, especially in the detection of the angular velocity of rotating objects. On the other hand, optical fiber technology is widely applied in laser velocimetry from beam delivery to scattered light collection, aiding the miniaturization of instruments. Here we report the first all-fiber rotational Doppler velocimetry (AF-RDV) with a single probe based on a fabricated mode-sculpted fiber-optic element. The constructed AF-RDV can be operated in two reciprocal schemes wherein exchanging the illuminating mode and detected mode. Using this, we experimentally demonstrate the mode-changing dependent nature of the RDE. Particularly, the results suggest that the rotational Doppler shift can be observed by mode-filtering the scattered signal even with a non-twisted probe light. We also show the achromatic property of the RDE by scanning the incident wavelength, enabling the AF-RDV within an ultra-broadband operation range. The AF-RDV exhibits favorable performance for detecting spinning rough surfaces. It may provide an exciting new practical sensing instrument with significant prospects for monitoring angular motion in both research and industry.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0