生命科学最新文献

{"title":"Effects of chromatic light interventions and wavelengths on ocular biometry in human myopia: A systematic review and meta-analysis","authors":"Azfira Hussain ,&nbsp;Jose J Estevez ,&nbsp;Nicola S Anstice ,&nbsp;Alessandro Papandrea ,&nbsp;Feier Yang ,&nbsp;Konogan Baranton ,&nbsp;Eleonore Pic ,&nbsp;Pascale Lacan ,&nbsp;Sayantan Biswas ,&nbsp;Ranjay Chakraborty","doi":"10.1016/j.jpap.2025.100268","DOIUrl":"10.1016/j.jpap.2025.100268","url":null,"abstract":"<div><div>Studies highlight the use of different wavelengths of light as emerging interventions to slow myopia progression in children. This review evaluates the effects of different wavelengths of chromatic light interventions on ocular biometry in humans. A literature search of MEDLINE, CINAHL, Scopus, ProQuest Central, Web of Science, and trial registries identified thirty-seven studies examining the effects of either long-term (4 weeks- 24 months) or short-term (between 10–120 min and ≤ 4 weeks) monochromatic light exposure. A random-effects model was used to calculate the weighted mean difference (WMD) and 95 % confidence intervals (CI) in spherical equivalent refraction (SER), axial length (AL) and subfoveal choroidal thickness (ChT). In studies examining long-term exposure to both long- and short-wavelength light, significant changes in AL, SER, and ChT were observed primarily with long-wavelength red light used in repeated low-level red light (RLRL) therapy. RLRL resulted in a significant reduction in AL and SER, and an increase in subfoveal ChT compared to a control group wearing single vision spectacles (SVS) at both 6 and 12 months (WMD at 6 and 12 months, AL:0.24 and –0.36 mm; SER: 0.31 and 0.77 D; ChT: +32.12 and +31.78 µm). Exposure to short-wavelength (blue and/or violet light) resulted in only a modest change in AL and myopia progression in children [mean change (95 % CI) at 12 months, AL:0.04 mm (–0.15 to 0.07); SER: 0.04 D (–0.16 to 0.24)]. Short-term exposure to both long- and short-wavelengths on ocular biometry in young adults showed equivocal results. LED-based blue light (454–456 nm) induced choroidal thickening and a reduction in AL, whereas red light produced the opposite effects. In conclusion, longer-term exposure to RLRL and violet light can slow myopia progression in children, with RLRL showing a stronger effect. Short-term exposure to different wavelengths offers insights for developing newer light-based myopia therapies.</div></div>","PeriodicalId":375,"journal":{"name":"Journal of Photochemistry and Photobiology","volume":"29 ","pages":"Article 100268"},"PeriodicalIF":3.261,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144535802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arabidopsis thaliana root responses to Cd exposure: insights into root tip-specific changes and the role of HY5 in limiting Cd accumulation and promoting tolerance","authors":"Ludwig Richtmann,&nbsp;Santiago Prochetto,&nbsp;Noémie Thiébaut,&nbsp;Manon C. M. Sarthou,&nbsp;Stéphanie Boutet,&nbsp;Marc Hanikenne,&nbsp;Stephan Clemens,&nbsp;Nathalie Verbruggen","doi":"10.1111/tpj.70298","DOIUrl":"https://doi.org/10.1111/tpj.70298","url":null,"abstract":"<div>\u0000 \u0000 <p>Cadmium (Cd) is a major environmental pollutant with high toxicity. While Cd exposure reduces root growth, its specific impact on the root meristem and differentiating parts remains poorly understood. This study investigates the spatial and temporal responses of <i>Arabidopsis thaliana</i> roots to Cd stress by dividing roots into root tips (RT) and remaining roots (RR) and employing transcriptomic, ionomic, and metabolomic analyses. Cd exposure altered mineral profiles, with RT accumulating less Cd but showing distinct changes in other elements compared to RR. Metabolomic analysis revealed root part-specific changes in phytochelatins, flavonoids, and glucosinolates. Transcriptomic data highlighted constitutive differences between RT and RR, reflecting functional specialization. Also, they revealed Cd-induced root part-specific and time-dependent transcriptional responses, including modulation of Fe-related genes. Phenotypic validation identified ELONGATED HYPOCOTYL 5 as a key regulator limiting Cd accumulation and promoting tolerance, as <i>hy5</i> mutants exhibited increased Cd sensitivity and accumulation. Additionally, mutants of genes regulated by HY5, such as xyloglucan endotransglucosylase/hydrolase genes (<i>XTH</i>) and <i>MYB12</i>, also showed altered root growth under Cd stress, implicating cell wall remodeling and flavonoid biosynthesis in Cd responses. This study provides a spatially and temporally resolved understanding of Cd's impact on root growth, and highlights HY5's role in Cd tolerance, thereby advancing our knowledge of plant responses to trace metal excess.</p>\u0000 </div>","PeriodicalId":233,"journal":{"name":"The Plant Journal","volume":"122 6","pages":""},"PeriodicalIF":6.2,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144492716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genome-wide association analysis and linkage mapping decipher the genetic control of primary metabolites and quality traits in Capsicum","authors":"Julia von Steimker,&nbsp;Regina Wendenburg,&nbsp;Annabella Klemmer,&nbsp;Macellaro Rosaria,&nbsp;Alisdair R. Fernie,&nbsp;Saleh Alseekh,&nbsp;Pasquale Tripodi","doi":"10.1111/tpj.70300","DOIUrl":"https://doi.org/10.1111/tpj.70300","url":null,"abstract":"<p>Pepper (<i>Capsicum</i> spp.) is a rich source of natural compounds, including primary metabolites essential for plants and influencing human nutrition and taste perception. Although pepper represents an important horticultural crop, the genetic bases underlying the primary metabolism remain largely unclear. Here, we performed a complementary approach for mapping primary metabolites via quantitative trait loci analysis (mQTL) and genome-wide association studies (mGWAS). Using gas chromatography coupled with mass spectrometry we quantified and mapped 80 metabolites, including amino acids, sugars, and organic acids in an interspecific backcross inbred line population and a GWAS panel over three independent trials. We identified 263 candidate genes implicated in 91 robust QTL across studies. Additionally, 28 QTL containing 84 candidate genes were identified with various pleiotropic effects. We further combined agro-physiological characteristics determining their relationships with metabolites, both underlying the quality of pepper fruits. We implemented plasticity analysis to investigate candidate genes causal for metabolic dispersion. Eighty-six genes were identified; among these, a previously reported UDP-glycosyltransferase responsible for capsianosides biosynthesis was found to be associated with a cluster of sugars, organic, and amino acids, which are the main precursors of sensory taste in vegetables. This study provides the first attempt to comprehend the genetic basis of <i>Capsicum</i> primary metabolism, which will further support assisted breeding for fruit quality.</p>","PeriodicalId":233,"journal":{"name":"The Plant Journal","volume":"122 6","pages":""},"PeriodicalIF":6.2,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/tpj.70300","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144492717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease.","authors":"Lisa Longo, Maria Assunta Costa, Rita Carrotta, Maria Rosalia Mangione, Vincenzo Martorana, Marco Tutone, Maria Grazia Ortore, Paula M Garcia-Franco, Sonia Vega, Adrian Velazquez-Campoy, Rosa Passantino, Silvia Vilasi","doi":"10.1007/s00249-025-01777-5","DOIUrl":"https://doi.org/10.1007/s00249-025-01777-5","url":null,"abstract":"<p><p>Vitamin B12 (cobalamin, Cbl) is a coordination compound of the cobalt, located at the center of a corrin ring composed of four pyrrolic-like groups. The cobalt ion can be bound to a variety of upper axial ligands, which vary among different cobalamin forms, including hydroxocobalamin (OHCbl), cyanocobalamin (CNCbl), methylcobalamin (MeCbl), and adenosylcobalamin (AdoCbl). MeCbl and AdoCbl are considered the biologically active forms, serving as cofactors in the metabolism of methylmalonic acid (MMA) and homocysteine (HCY). Impaired conversion of these metabolites leads to their pathological accumulation, resulting in severe cellular damage. This is precisely what occurs in cblC deficiency, a rare inborn disorder caused by mutations in the MMACHC protein, which plays a crucial role in binding and processing the various cobalamin forms. Mutations affecting MMACHC function impair its ability to correctly handle cobalamins, leading to the disease. In this study, we evaluated the impact of various cobalamin forms, specifically AdoCbl, MeCbl, and CNCbl, on the stability and oligomeric organization of the wild type MMACHC protein, using circular dichroism spectroscopy, native gel electrophoresis, and small-angle X-ray scattering. Moreover, isothermal titration calorimetry experiments provided insights into the thermodynamic parameters governing MMACHC binding to these cobalamins. In addition, we also assessed how the R161Q mutation in MMACHC alters the affinity of this protein for the different vitamin B12 forms, leading to decreased stability and impaired homodimerization, a process likely relevant to its functional role. Our findings provide molecular insights into cblC pathogenesis and advance our understanding of MMACHC structure-function relationships.</p>","PeriodicalId":548,"journal":{"name":"European Biophysics Journal","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Soybean Resistance to Atrazine Stress Through Seed Coating With Atrazine-Degrading Paenarthrobacter sp. AT5.","authors":"Xin Wen, Chao He, Yuhao Fu, Leilei Xiang, Jean Damascene Harindintwali, Yu Wang, Siqi Wei, Maoyuan Liao, Jiandong Jiang, Xin Jiang, Ravi Naidu, Fang Wang","doi":"10.1111/pce.70033","DOIUrl":"https://doi.org/10.1111/pce.70033","url":null,"abstract":"<p><p>Shifting from maize monoculture to maize-soybean rotation or intercropping is a key strategy to boost soybean self-sufficiency. However, the residual atrazine in soils, resulting from the extensive use of atrazine in long-term maize monocultures, poses a significant threat to soybean productivity, requiring immediate solutions. This study introduces a novel seed-coating method using atrazine-degrading Paenarthrobacter sp. AT5 to mitigate the adverse effects of atrazine on soybean growth. The efficacy of seed coating in reducing atrazine accumulation in seedlings and promoting seedling growth was found to vary depending on the growth stage and atrazine concentration in the soil. At low atrazine concentrations (close to safe levels for soybeans), the seed coating reduced leaf atrazine concentrations by 30.7%-46.0% at the cotyledon growth stage (VC). At high atrazine concentrations, the shoot atrazine concentrations decreased by 60.9%-88.4% at the emergence growth stage (VE) and seedling biomass was significantly increased in the VC stage. This is associated with the influence of seed coating on rhizosphere metabolites, which activate the plant defence system and recruit atrazine-degrading and plant-beneficial bacteria. This study offers comprehensive insights into the potential of seed coating with strain AT5 as a scalable solution for mitigating atrazine toxicity in soybeans.</p>","PeriodicalId":222,"journal":{"name":"Plant, Cell & Environment","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Getting out of a hairy situation: Increased trichome density improves pest resilience in tomato","authors":"Martin Balcerowicz","doi":"10.1111/tpj.70302","DOIUrl":"https://doi.org/10.1111/tpj.70302","url":null,"abstract":"&lt;p&gt;The plant epidermis serves as a crucial interface between the aerial parts of the plant and the external environment. It regulates interactions with the surroundings and provides protection against abiotic stress, pests and pathogens. Trichomes—small, often hair-like appendages—play an important role in these protective functions. They are classified as either glandular or non-glandular based on their ability to produce, store and secrete specialized metabolites, and can be further divided into eight distinct types based on morphology (Khan et al., &lt;span&gt;2021&lt;/span&gt;). Glandular trichomes produce biologically and commercially important chemicals such as essential oils, cannabinoids, alkaloids and terpenes, many of which have roles in defence and deter pathogens and herbivores. Understanding how glandular trichomes are formed and patterned is thus not only a fundamental question in plant developmental biology but also holds promise for agricultural and pharmaceutical applications (Huchelmann et al., &lt;span&gt;2017&lt;/span&gt;).&lt;/p&gt;&lt;p&gt;Glandular trichomes are multicellular and arise from epidermal cells that receive developmental cues from surrounding tissues. These cells then undergo a series of tightly regulated divisions and differentiation events to form the mature trichome, consisting of a base, a stalk and a glandular head. Since &lt;i&gt;Arabidopsis thaliana&lt;/i&gt; does not produce glandular trichomes, researchers have turned to other model systems to study their development. In tomato (&lt;i&gt;Solanum lycopersicum&lt;/i&gt;), the homeodomain-Leu zipper IV (HD-ZIP) transcription factor Woolly (Wo) regulates the formation of Type I trichomes (Wu et al., &lt;span&gt;2024&lt;/span&gt;), which are characterized by a multicellular stalk and a single glandular head cell, while the bHLH transcription factor SlMYC1 controls the formation of Type VI trichomes (Xu et al., &lt;span&gt;2018&lt;/span&gt;), which feature four glandular head cells. Despite the discovery of these factors, the regulatory networks guiding glandular trichome development remain incompletely understood and additional components are yet to be identified.&lt;/p&gt;&lt;p&gt;Baowen Huang and Zhenguo Li from Chongqing University have extensive experience in tomato breeding and improvement, while Julien Pirrello, based at the Université de Toulouse, studies transcriptional regulation in tomato. The groups have a longstanding partnership, spanning more than 20 years and involving multiple student exchanges between the laboratories. The highlighted study represents one output of this partnership: Shi et al. investigated genes selectively expressed in glandular trichomes to identify new regulators of trichome development. They found that the GAI, RGA and SCR (GRAS) family transcription factor Sl&lt;i&gt;GRAS9&lt;/i&gt; was highly expressed in Type VI trichomes but showed low expression in non-glandular trichomes and surrounding leaf tissue. Across a range of tomato cultivars, Sl&lt;i&gt;GRAS9&lt;/i&gt; transcript levels were inversely correlated with Type VI trichome densit","PeriodicalId":233,"journal":{"name":"The Plant Journal","volume":"122 6","pages":""},"PeriodicalIF":6.2,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/tpj.70302","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144492684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ZmMYB92 modulates secondary wall cellulose synthesis in maize","authors":"Xiao Zhang,&nbsp;Haiyan Li,&nbsp;Chengyang Zhao,&nbsp;Ying Wu,&nbsp;Xiaoduo Lu","doi":"10.1111/tpj.70296","DOIUrl":"https://doi.org/10.1111/tpj.70296","url":null,"abstract":"<div>\u0000 \u0000 <p>Lodging resistance, a pivotal determinant for crop stability and yield of maize, is chiefly governed by the mechanical attributes of cell walls, particularly the secondary cell walls (SCWs). Cellulose, the predominant constituent of SCWs, serves a vital function in physical support. Despite its significance, the regulatory mechanisms orchestrating SCW cellulose biosynthesis in maize remain elusive. In this investigation, we identify and characterize ZmMYB92, a transcription factor (TF) from the R2R3-MYB family, as a pivotal regulator of SCW biosynthesis in maize. Mutations in ZmMYB92 result in an altered phenotype characterized by increased stem brittleness, diminished cellulose content, and thinner cell walls, especially in stems and leaf veins. ZmMYB92 directly binds to the <i>cis</i> elements of the <i>ZmCesA10</i> and <i>ZmCesA11</i> promoters to activate their expression. The transcriptionally binding <i>cis</i> elements of ZmMYB92 are summarized. These findings provide a foundation for further modulation of cell wall properties and subsequent maize improvement.</p>\u0000 </div>","PeriodicalId":233,"journal":{"name":"The Plant Journal","volume":"122 6","pages":""},"PeriodicalIF":6.2,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144492715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MhNF-YA1-Like-MhDnaJC76-MhAAO3 Transcriptional Cascade Enhances ABA Biosynthesis and Drought Tolerance in Apple.","authors":"Jianwen Tian, Chunhui Song, Xiang Gao, Juan Gong, Lulu Yu, Xinwu Tian, Kunxi Zhang, Jian Jiao, Miaomiao Wang, Pengbo Hao, Xianbo Zheng, Tuanhui Bai","doi":"10.1111/pce.70029","DOIUrl":"https://doi.org/10.1111/pce.70029","url":null,"abstract":"<p><p>Drought, the most unfavorable and widespread environmental factor among abiotic stresses, has become a significant global issue that severely crop growth and yield. Nuclear factor-Y (NF-Y) transcription factors have well-documented functions in regulating stress tolerance in plants. However, the specific functions and molecular mechanisms of NF-YS in conferring drought tolerance in apples remain largely unexplored. Here, we reported that the NF-Y transcription factor MhNF-YA1-like positively modulates drought stress tolerance in apple (Malus domestica Borkh.). MhNF-YA1-like is transcriptionally upregulated in response to drought and abscisic acid (ABA) treatments. Overexpression of MhNF-YA1-like enhances drought tolerance in apples, whereas its silencing results in weakened drought tolerance. Further investigation reveals that MhNF-YA1-like directly binds to the promoter of MhAAO3 and activates its expression. Additionally, we identified MhDnaJC76 as an interacting protein of MhNF-YA1, and MhDnaJC76 positively modulates apple drought tolerance. Furthermore, the interaction between MhNF-YA1-like and MhDnaJC76 significantly amplifies the regulatory effect of MhNF-YA1-like on MhAAO3, thereby promoting ABA accumulation and consequently enhancing apple drought tolerance. Taken together, our findings elucidate a molecular framework by which the MhNF-YA1-like-MhDnaJC76 complex modulates drought tolerance in apples, thereby providing targets for developing drought-tolerant crops.</p>","PeriodicalId":222,"journal":{"name":"Plant, Cell & Environment","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Germination of Peanut Seeds Promoted by an Endophytic Priestia megaterium PH3 via Activating ROS and Hormone Metabolism Pathway Under Salt Stress.","authors":"Zilong Li, Jiamin Jiang, Keyu Sun, Shuhong Ye","doi":"10.1111/pce.70040","DOIUrl":"https://doi.org/10.1111/pce.70040","url":null,"abstract":"<p><p>Salt stress poses a significant threat to global agriculture by inhibiting seed germination and impeding early seedling development. This study investigates the role of the endophytic bacterium Priestia megaterium PH3 in alleviating salt stress during peanut seed germination. P. megaterium PH3 effectively colonised peanut seeds, leading to enhanced germination rates and root elongation under 200 mM NaCl stress. Mechanistically, the endophyte modulated the reactive oxygen species (ROS) metabolism system, evidenced by increased activity of antioxidant enzymes (SOD, CAT, POD, APX, DHAR, MDHAR, and GR), elevated levels of nonenzymatic antioxidants (AsA and GSH), and reduced accumulation of H₂O₂ and O₂ ^•-. Notably, P. megaterium PH3 upregulated the expression of genes related to melatonin (MEL) biosynthesis (AhASMT1, AhASMT2, AhASMT3, AhTDC, AhT5H), contributing to increased MEL content. Furthermore, the endophyte influenced hormonal balance by promoting the expression of genes involved in abscisic acid (ABA) catabolism (AhCYP707A1) and gibberellin (GA) synthesis (AhGA20ox, AhGA3ox). Untargeted metabolomics analysis revealed that under salt stress, P. megaterium PH3 shifted its tryptophan metabolism, leading to decreased levels of indole-3-acetic acid (IAA) precursors and increased levels of MEL precursors. Correlation analysis highlighted a significant relationship between MEL levels, ABA and GA metabolism, and antioxidant enzyme activity. These findings suggest that P. megaterium PH3 enhances peanut seed germination under salt stress through a multifaceted approach involving ROS scavenging, hormonal regulation, and metabolic reprogramming. This study provides valuable insights into the potential of P. megaterium PH3 as a bio-inoculant to improve crop establishment and productivity in saline environments.</p>","PeriodicalId":222,"journal":{"name":"Plant, Cell & Environment","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of paternal Oryza sativa Baby Booms (OsBBMs) in initiating de novo gene expression and regulating early zygotic development in rice","authors":"Nargis Akter,&nbsp;Takumi Tezuka,&nbsp;Kasidit Rattanawong,&nbsp;Aya Satoh,&nbsp;Atsuko Kinoshita,&nbsp;Yutaka Sato,&nbsp;Takashi Okamoto","doi":"10.1111/tpj.70305","DOIUrl":"https://doi.org/10.1111/tpj.70305","url":null,"abstract":"<p><i>Oryza sativa</i> BABY BOOM 1 (OsBBM1), a member of the AP2/ERF family of transcription factors, is expressed from paternal allele in rice zygote and plays a crucial role in initiating zygotic development. However, the mechanism how the paternal OsBBM1 drives this development remains unclear. Rice zygotes with four different gamete combinations with or without functional paternal OsBBMs were produced by electrofusion, using gametes isolated from <i>bbms</i> triple mutants and wild-type rice plants. Developmental and gene expression profiles of these types of zygotes were intensively analyzed and compared. Mutations in <i>OsBBM1</i>, <i>OsBBM2</i>, and <i>OsBBM3</i> on the paternal alleles caused developmental arrest or delay in the zygotes, while defects in <i>OsBBMs</i> on the maternal allele had minimal effects on zygotic development. Paternal allele of <i>OsBBMs</i> significantly influenced gene expression profiles related to regulation of basic cellular processes, such as chromosome/chromatin organization/assembly and cell cycle/division compared to the maternal allele of <i>OsBBMs</i>. Majority of these genes were upregulated in zygotes from paternal/parental alleles via paternal <i>OsBBMs</i>. Paternal <i>OsBBMs</i> initiate early development of rice zygotes through the regulation of expression profiles of genes controlling status of chromosome/chromatin and cell cycle/division.</p>","PeriodicalId":233,"journal":{"name":"The Plant Journal","volume":"122 6","pages":""},"PeriodicalIF":6.2,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/tpj.70305","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144492666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}