Hamdi M Al-Said, Ahmed Alghamdi, Sami S Ashgar, Naif A Jalal, Hani S Faidah, Ayman K Johargy, Aiman M Momenah, Abeer A Barhameen, Sumyya H Hariri, Farkad Bantun, Essa Althobiany, Elshiekh B Khidir
{"title":"沙特阿拉伯一家三级护理医院术后伤口感染中耐药性细菌病原体的分离和检测。","authors":"Hamdi M Al-Said, Ahmed Alghamdi, Sami S Ashgar, Naif A Jalal, Hani S Faidah, Ayman K Johargy, Aiman M Momenah, Abeer A Barhameen, Sumyya H Hariri, Farkad Bantun, Essa Althobiany, Elshiekh B Khidir","doi":"10.4103/sjmms.sjmms_405_22","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Surgical site infections (SSIs), especially when caused by multidrug-resistant (MDR) bacteria, are a major healthcare concern worldwide. For optimal treatment and prevention of antimicrobial resistance, it is important for clinicians to be aware of local drug-resistant bacterial pathogens that cause SSIs.</p><p><strong>Objective: </strong>To determine the frequency patterns of drug-resistant bacterial strains causing SSIs at a tertiary care hospital in Saudi Arabia.</p><p><strong>Methods: </strong>This retrospective study was conducted at the Microbiology laboratory of Al-Noor Specialist Hospital, Makkah, Saudi Arabia, and included wound swab samples from all cases of SSI between January 01, 2017, and December 31, 2021. The swabs were processed for the identification of bacterial strains and their resistance pattern to antibiotics according to the Clinical and Laboratory Standards Institute.</p><p><strong>Results: </strong>A total of 5409 wound swabs were analyzed, of which 3604 samples (66.6%) were from male. Most samples were from the Department of Surgery (43.3%). A total of 14 bacterial strains were isolated, of which 9 were Gram-negative bacteria. The most common isolates were <i>Klebsiella pneumoniae</i>, followed by <i>Pseudomonas aeruginosa</i>, <i>Escherichia coli</i>, <i>Acinetobacter baumannii</i>, methicillin-resistant <i>Staphylococcus aureus</i> (MRSA), vancomycin-resistant Enterococci (VRE), and vancomycin-resistant <i>S. aureus</i> (VRSA). In terms of MDR in 2021, the highest rate of carbapenem-resistance was in <i>A. baumannii</i> (97%). MDR was as follows: <i>A. baumannii</i>, 97%; <i>K. pneumoniae</i>, 81%; <i>E. coli</i>, 71%; MRSA, 60%; <i>P. aeruginosa</i>, 33%; VRE, 22%; and VRSA, 2%.</p><p><strong>Conclusion: </strong>This study showed that in the city of Makkah, Saudi Arabia, the rates of MDR bacteria are high, with the majority being Gram-negative.</p>","PeriodicalId":21442,"journal":{"name":"Saudi Journal of Medicine & Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/65/SJMMS-11-229.PMC10393095.pdf","citationCount":"1","resultStr":"{\"title\":\"Isolation and Detection of Drug-Resistant Bacterial Pathogens in Postoperative Wound Infections at a Tertiary Care Hospital in Saudi Arabia.\",\"authors\":\"Hamdi M Al-Said, Ahmed Alghamdi, Sami S Ashgar, Naif A Jalal, Hani S Faidah, Ayman K Johargy, Aiman M Momenah, Abeer A Barhameen, Sumyya H Hariri, Farkad Bantun, Essa Althobiany, Elshiekh B Khidir\",\"doi\":\"10.4103/sjmms.sjmms_405_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Surgical site infections (SSIs), especially when caused by multidrug-resistant (MDR) bacteria, are a major healthcare concern worldwide. For optimal treatment and prevention of antimicrobial resistance, it is important for clinicians to be aware of local drug-resistant bacterial pathogens that cause SSIs.</p><p><strong>Objective: </strong>To determine the frequency patterns of drug-resistant bacterial strains causing SSIs at a tertiary care hospital in Saudi Arabia.</p><p><strong>Methods: </strong>This retrospective study was conducted at the Microbiology laboratory of Al-Noor Specialist Hospital, Makkah, Saudi Arabia, and included wound swab samples from all cases of SSI between January 01, 2017, and December 31, 2021. The swabs were processed for the identification of bacterial strains and their resistance pattern to antibiotics according to the Clinical and Laboratory Standards Institute.</p><p><strong>Results: </strong>A total of 5409 wound swabs were analyzed, of which 3604 samples (66.6%) were from male. Most samples were from the Department of Surgery (43.3%). A total of 14 bacterial strains were isolated, of which 9 were Gram-negative bacteria. The most common isolates were <i>Klebsiella pneumoniae</i>, followed by <i>Pseudomonas aeruginosa</i>, <i>Escherichia coli</i>, <i>Acinetobacter baumannii</i>, methicillin-resistant <i>Staphylococcus aureus</i> (MRSA), vancomycin-resistant Enterococci (VRE), and vancomycin-resistant <i>S. aureus</i> (VRSA). In terms of MDR in 2021, the highest rate of carbapenem-resistance was in <i>A. baumannii</i> (97%). MDR was as follows: <i>A. baumannii</i>, 97%; <i>K. pneumoniae</i>, 81%; <i>E. coli</i>, 71%; MRSA, 60%; <i>P. aeruginosa</i>, 33%; VRE, 22%; and VRSA, 2%.</p><p><strong>Conclusion: </strong>This study showed that in the city of Makkah, Saudi Arabia, the rates of MDR bacteria are high, with the majority being Gram-negative.</p>\",\"PeriodicalId\":21442,\"journal\":{\"name\":\"Saudi Journal of Medicine & Medical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/65/SJMMS-11-229.PMC10393095.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Saudi Journal of Medicine & Medical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/sjmms.sjmms_405_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/7/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Saudi Journal of Medicine & Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/sjmms.sjmms_405_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/7/15 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Isolation and Detection of Drug-Resistant Bacterial Pathogens in Postoperative Wound Infections at a Tertiary Care Hospital in Saudi Arabia.
Background: Surgical site infections (SSIs), especially when caused by multidrug-resistant (MDR) bacteria, are a major healthcare concern worldwide. For optimal treatment and prevention of antimicrobial resistance, it is important for clinicians to be aware of local drug-resistant bacterial pathogens that cause SSIs.
Objective: To determine the frequency patterns of drug-resistant bacterial strains causing SSIs at a tertiary care hospital in Saudi Arabia.
Methods: This retrospective study was conducted at the Microbiology laboratory of Al-Noor Specialist Hospital, Makkah, Saudi Arabia, and included wound swab samples from all cases of SSI between January 01, 2017, and December 31, 2021. The swabs were processed for the identification of bacterial strains and their resistance pattern to antibiotics according to the Clinical and Laboratory Standards Institute.
Results: A total of 5409 wound swabs were analyzed, of which 3604 samples (66.6%) were from male. Most samples were from the Department of Surgery (43.3%). A total of 14 bacterial strains were isolated, of which 9 were Gram-negative bacteria. The most common isolates were Klebsiella pneumoniae, followed by Pseudomonas aeruginosa, Escherichia coli, Acinetobacter baumannii, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE), and vancomycin-resistant S. aureus (VRSA). In terms of MDR in 2021, the highest rate of carbapenem-resistance was in A. baumannii (97%). MDR was as follows: A. baumannii, 97%; K. pneumoniae, 81%; E. coli, 71%; MRSA, 60%; P. aeruginosa, 33%; VRE, 22%; and VRSA, 2%.
Conclusion: This study showed that in the city of Makkah, Saudi Arabia, the rates of MDR bacteria are high, with the majority being Gram-negative.
期刊介绍：
Saudi Journal of Medicine & Medical Sciences (SJMMS) is the official scientific journal of Imam Abdulrahman Bin Faisal University. It is an international peer-reviewed, general medical journal. The scope of the Journal is to publish research that will be of interest to health specialties both in academic and clinical practice. The Journal aims at disseminating high-powered research results with the objective of turning research into knowledge. It seeks to promote scholarly publishing in medicine and medical sciences. The Journal is published in print and online. The target readers of the Journal include all medical and health professionals in the health cluster such as in medicine, dentistry, nursing, applied medical sciences, clinical pharmacology, public health, etc.
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