阿片类激动剂治疗患者身体发病率的性别差异:来自捷克共和国和挪威的基于人群的队列研究。

IF 3 3区 医学 Q2 SUBSTANCE ABUSE
Gabriela Rolová, Desiree Eide, Roman Gabrhelík, Ingvild Odsbu, Thomas Clausen, Svetlana Skurtveit
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引用次数: 0

摘要

背景:身体疾病是阿片受体激动剂治疗(OAT)患者的一个重要负担。本研究描述了两个国家OAT患者群体的生理发病率,重点关注性别差异。方法:这项基于人群的队列研究连接了多个健康登记,调查了2010-2019年捷克共和国(N = 4,280)和挪威(N = 11,389)接受OAT的患者的身体疾病(ICD-10)。进行性别分层分析。结果:总体而言,我们发现不同性别的OAT患者存在较大的身体发病率负担。在捷克共和国和挪威,OAT地区的妇女在大多数诊断章节中患身体疾病的比例要高得多,特别是泌尿生殖系统疾病和肿瘤。伤害/外因和传染病/寄生虫病是男女中最常见的疾病。病毒性肝炎占两个队列中女性和男性感染性发病率的一半以上。结论:我们的研究结果支持需要跨器官系统的疾病和病症的早期筛查、检测和治疗,以及整合健康促进活动来降低OAT患者的身体发病率。性别差异突出表明,需要有针对性地解决具体的医疗状况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Gender differences in physical morbidity in opioid agonist treatment patients: population-based cohort studies from the Czech Republic and Norway.

Gender differences in physical morbidity in opioid agonist treatment patients: population-based cohort studies from the Czech Republic and Norway.

Background: Physical diseases represent a significant burden for opioid agonist treatment (OAT) patients. This study described physical morbidity in two national cohorts of OAT patients focusing on gender differences.

Methods: This population-based cohort study linking multiple health registers investigated physical diseases (ICD-10) in patients receiving OAT in the Czech Republic (N = 4,280) and Norway (N = 11,389) during 2010-2019. Gender-stratified analysis was performed.

Results: Overall, we found a large burden of physical morbidity across gender groups in OAT patients. In the Czech Republic and Norway, women in OAT had a significantly higher prevalence of physical diseases across most diagnostic chapters, notably genitourinary diseases and neoplasms. Injuries/external causes and infectious/parasitic diseases were among the most common diseases in both women and men. Viral hepatitis accounted for over half of infectious morbidity in women and men in both cohorts.

Conclusions: Our findings support the need for early screening, detection, and treatment of diseases and conditions across organ systems and the integration of health promotion activities to reduce physical morbidity in OAT patients. The gender differences underline the need for a tailored approach to address specific medical conditions.

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来源期刊
CiteScore
5.20
自引率
0.00%
发文量
73
审稿时长
19 weeks
期刊介绍: Substance Abuse Treatment, Prevention, and Policy is an open access, peer-reviewed journal that encompasses research concerning substance abuse, with a focus on policy issues. The journal aims to provide an environment for the exchange of ideas, new research, consensus papers, and critical reviews, to bridge the established fields that share a mutual goal of reducing the harms from substance use. These fields include: legislation pertaining to substance use; correctional supervision of people with substance use disorder; medical treatment and screening; mental health services; research; and evaluation of substance use disorder programs.
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