从自闭症成人之间的差异中发现相似之处:两个复制分组

IF 3.2 2区 心理学 Q1 PSYCHOLOGY, DEVELOPMENTAL
Tulsi A Radhoe, Joost A Agelink van Rentergem, Carolien Torenvliet, Annabeth P Groenman, Wikke J van der Putten, Hilde M Geurts
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引用次数: 0

摘要

自闭症具有异质性,这使得提供量身定制的支持和未来前景变得复杂。我们的目标是在智力处于中上水平的成年自闭症患者中找出亚群,以明确某些亚群是否需要支持。我们纳入了 14 个与老龄化和/或自闭症有关的问卷变量(如人口、心理和生活方式)。社区检测分析用于识别原始样本中的亚组,原始样本包括 114 名成年后被诊断患有自闭症的成年人(自闭症)和 58 名作为对比组的非自闭症成年人(COMP),以及一个复制样本(NAutism = 261;NCOMP = 287),年龄均为 30-89 岁。接下来,我们在自闭症样本中确定了亚组,并评估了外部有效性(认知和心理障碍以及生活质量 [QoL])。为了测试特异性,我们在加入了 123 名患有多动症(ADHD)、年龄在 30-80 岁之间的成年人后重复了上述分析。不出所料,自闭症组和 COMP 组形成了不同的亚组。在自闭症成人中,我们发现了三个亚组,其中两个得到了重复。其中一个亚组在群集变量方面似乎最为脆弱;这个亚组也报告了最多的认知和心理困难,以及最低的 QoL。加入多动症组并没有改变结果。在成人自闭症患者中,有一个亚组可能会特别受益于支持和专门护理,但这必须在今后的研究中进行检验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Finding Similarities in Differences Between Autistic Adults: Two Replicated Subgroups.

Autism is heterogeneous, which complicates providing tailored support and future prospects. We aim to identify subgroups in autistic adults with average to high intelligence, to clarify if certain subgroups might need support. We included 14 questionnaire variables related to aging and/or autism (e.g., demographic, psychological, and lifestyle). Community detection analysis was used for subgroup identification in an original sample of 114 autistic adults with an adulthood diagnosis (autism) and 58 non-autistic adults as comparison group (COMP), and a replication sample (NAutism = 261; NCOMP = 287), both aged 30-89 years. Next, we identified subgroups and assessed external validity (for cognitive and psychological difficulties, and quality of life [QoL]) in the autism samples. To test specificity, we repeated the analysis after adding 123 adults with ADHD, aged 30-80 years. As expected, the autism and COMP groups formed distinct subgroups. Among autistic adults, we identified three subgroups of which two were replicated. One of these subgroups seemed most vulnerable on the cluster variables; this subgroup also reported the most cognitive and psychological difficulties, and lowest QoL. Adding the ADHD group did not alter results. Within autistic adults, one subgroup could especially benefit from support and specialized care, although this must be tested in future studies.

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来源期刊
CiteScore
8.00
自引率
10.30%
发文量
433
期刊介绍: The Journal of Autism and Developmental Disorders seeks to advance theoretical and applied research as well as examine and evaluate clinical diagnoses and treatments for autism and related disabilities. JADD encourages research submissions on the causes of ASDs and related disorders, including genetic, immunological, and environmental factors; diagnosis and assessment tools (e.g., for early detection as well as behavioral and communications characteristics); and prevention and treatment options. Sample topics include: Social responsiveness in young children with autism Advances in diagnosing and reporting autism Omega-3 fatty acids to treat autism symptoms Parental and child adherence to behavioral and medical treatments for autism Increasing independent task completion by students with autism spectrum disorder Does laughter differ in children with autism? Predicting ASD diagnosis and social impairment in younger siblings of children with autism The effects of psychotropic and nonpsychotropic medication with adolescents and adults with ASD Increasing independence for individuals with ASDs Group interventions to promote social skills in school-aged children with ASDs Standard diagnostic measures for ASDs Substance abuse in adults with autism Differentiating between ADHD and autism symptoms Social competence and social skills training and interventions for children with ASDs Therapeutic horseback riding and social functioning in children with autism Authors and readers of the Journal of Autism and Developmental Disorders include sch olars, researchers, professionals, policy makers, and graduate students from a broad range of cross-disciplines, including developmental, clinical child, and school psychology; pediatrics; psychiatry; education; social work and counseling; speech, communication, and physical therapy; medicine and neuroscience; and public health.
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