用于单细胞力学性能分析的MEMS传感器

2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS) Pub Date : 2020-01-01 DOI:10.1109/MEMS46641.2020.9056113

M. Kumemura, L. Kudo, Zhongcai Ma, S. Karsten

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引用次数: 0

摘要

我们开发了一种基于MEMS的传感器，Nanopin，用于单个贴壁细胞的机械表征。纳米粒子由与细胞形成接触的传感尖端、位移传感器和致动器组成。利用不同浓度的琼脂糖凝胶评估了传感的可行性，然后在不同的表面上对人癌细胞进行了刚度测量。在对细胞进行测量后，我们确认细胞在培养箱中正常生长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Nanopin - A MEMS Based Sensor for the Analysis of Single Cell Mechanical Properties

We developed a MEMS based sensor, Nanopin, for mechanical characterization of individual adherent cells. Nanopin consists of sensing tip that forms a contact with a cell, a displacement sensor, and an actuator. The feasibility of sensing was evaluated using various concentrations of agarose gel, and then the stiffness measurements of human carcinoma cells were conducted on different surfaces. After the measurements of cells, we confirmed that cells grow normally in an incubator.

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2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS)

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