评估双叶主动脉瓣对升主动脉的湍流影响。

IF 1.7 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Rukiye Kara, Christian Vergara
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引用次数: 0

摘要

有二尖叶的主动脉瓣有两个而不是三个小叶,这是一种先天性心脏病。大约0.5-2%的人有二尖主动脉瓣。通过主动脉的血流通常被认为是层流的,尽管主动脉瓣疾病会导致湍流过渡。了解湍流的影响对于预测疾病的进展至关重要。本研究的目的是使用大涡模拟对二叶主动脉瓣功能障碍的湍流进行全面分析。使用大涡模拟,比较了二尖瓣和三尖瓣主动脉瓣的血流模式,发现了显著差异。双叶构型的流速场向升主动脉不对称分布。另一方面,在三尖瓣主动脉瓣(TAV)中,流量在同一主动脉段内是对称的。此外,我们研究了每种情况下的标准偏差、Q准则、粘度比和壁剪切应力,以了解向湍流的过渡。我们的研究结果表明,在双叶主动脉瓣(BAV)病例中,流体动力学异常增加。还研究了TAV和BAV情景下的整体湍流动能和时间平均壁剪切应力。我们发现,与TAV相比,BAV情况下的整体湍流动能更高,此外BAV在升主动脉中引起的壁剪切应力增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessing turbulent effects in ascending aorta in presence of bicuspid aortic valve.

Aortic valves with bicuspids have two rather than three leaflets, which is a congenital heart condition. About 0.5-2% of people have a bicuspid aortic valve. Blood flow through the aorta is commonly believed to be laminar, although aortic valve disorders can cause turbulent transitions. Understanding the impact of turbulence is crucial for foreseeing how the disease will progress. The study's objective was use large eddy simulation to provide a thorough analysis of the turbulence in bicuspid aortic valve dysfunction. Using a large eddy simulation, the blood flow patterns of the bicuspid and tricuspid aortic valves were compared, and significant discrepancies were found. The velocity field in flow in bicuspid configurations was asymmetrically distributed toward the ascending aorta. In tricuspid aortic valve (TAV) the flow, on the other hand, was symmetrical within the same aortic segment. Moreover, we looked into standard deviation, Q-criterion, viscosity ratio and wall shear stresses for each cases to understand transition to turbulence. Our findings indicate that in the bicuspid aortic valve (BAV) case, the fluid-dynamic abnormalities increase. The global turbulent kinetic energy and time-averaged wall shear stress for the TAV and BAV scenarios were also examined. We discovered that the global turbulent kinetic energy was higher in the BAV case compared to TAV, in addition to the increased wall shear stress induced by the BAV in the ascending aorta.

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来源期刊
CiteScore
4.10
自引率
6.20%
发文量
179
审稿时长
4-8 weeks
期刊介绍: The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.
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