在工作记忆训练过程中,通过多次经颅直流电刺激持续提高神经效率。

IF 3.6 1区 心理学 Q1 EDUCATION & EDUCATIONAL RESEARCH
Yufeng Ke, Shuang Liu, Long Chen, Xiashuang Wang, Dong Ming
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引用次数: 0

摘要

多次经颅直流电刺激(tDCS)结合工作记忆训练(WMT)导致长期行为改善的神经基础尚不清楚。在这项研究中,我们使用任务相关脑电图(EEG)测量来研究在具有挑战性的WMT期间,在左背外侧前额叶皮层(dlPFC)上应用阳极高清晰度(HD)-tDCS的持久神经生理学影响。34名健康的年轻人被随机分为假tDCS组或活动tDCS组,并在连续10天内接受10次30分钟的训练,在前一次测试之前,然后分别在最后一次测试后一天和三周进行后一次测试,通过执行高负荷WM任务和脑电图记录。多会话HD tDCS显著增强了WMT的行为益处。与假手术组相比,活动组在训练结束时表现出θ、α、β和γ任务相关振荡的增加,并在训练后3周显著增加P300反应。我们的研究结果表明,在多会话WMT期间,在左侧dlPFC上应用阳极tDCS可以增强WMT的行为益处,并促进WM相关神经效率的持续提高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Lasting enhancements in neural efficiency by multi-session transcranial direct current stimulation during working memory training.

Lasting enhancements in neural efficiency by multi-session transcranial direct current stimulation during working memory training.

The neural basis for long-term behavioral improvements resulting from multi-session transcranial direct current stimulation (tDCS) combined with working memory training (WMT) remains unclear. In this study, we used task-related electroencephalography (EEG) measures to investigate the lasting neurophysiological effects of anodal high-definition (HD)-tDCS applied over the left dorsolateral prefrontal cortex (dlPFC) during a challenging WMT. Thirty-four healthy young adults were randomized to sham or active tDCS groups and underwent ten 30-minute training sessions over ten consecutive days, preceded by a pre-test and followed by post-tests performed one day and three weeks after the last session, respectively, by performing high-load WM tasks along with EEG recording. Multi-session HD-tDCS significantly enhanced the behavioral benefits of WMT. Compared to the sham group, the active group showed facilitated increases in theta, alpha, beta, and gamma task-related oscillations at the end of training and significantly increased P300 response 3 weeks post-training. Our findings suggest that applying anodal tDCS over the left dlPFC during multi-session WMT can enhance the behavioral benefits of WMT and facilitate sustained improvements in WM-related neural efficiency.

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来源期刊
CiteScore
5.40
自引率
7.10%
发文量
29
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