幽门杆菌病患儿胃肠道的内镜改变

IF 1 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
S. Turdieva
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引用次数: 0

摘要

背景:在世界范围内,慢性胃十二指肠病变(CGDP)在儿童中的发病率为3.2% ~ 52%,仅次于呼吸系统疾病。主要病原体为幽门螺杆菌(HP),研究这些儿童胃和十二指肠的内镜变化仍然是一个重要的问题。本研究探讨了食管胃十二指肠镜(EGD)检查儿童CGDP上消化道粘膜层的变化及其在HP感染中的特征。方法:对128例6 ~ 15岁儿童进行CGDP检查。所有患者均行EGD检查,胃和十二指肠可见粘膜。HP感染的研究通过两种方法进行:呼吸试验和免疫层析粪便试验。结果:胃肠道溃疡性病变患者幽门螺杆菌感染率高于炎症性病变患者(平均1:6 . 0)。HP感染患者胃食管反流和十二指肠胃反流发生率高。幽门螺杆菌感染儿童以胃窦和胃体、球和十二指肠远端萎缩病变为主。结论:幽门螺杆菌感染患儿发生胃溃疡和十二指肠溃疡的几率比未感染患儿高94% (P<0.005),胃十二指肠反流发生率为77.6%,十二指肠胃反流发生率为67.4%,胃肠道粘膜层萎缩性改变发生率为4倍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endoscopic changes in the gastrointestinal tract in children with helicobacteriosis
Background: All over the world, chronic gastroduodenal pathology (CGDP) occurs in children from 3.2% to 52% and takes 2nd place after diseases of the respiratory system. The main pathogen is Helicobacter pylori (HP), and the problem of studying endoscopic changes in the stomach and duodenum in n these children remains relevant. This study investigated changes observed by esophagogastroduodenoscopy (EGD) examination of the mucous layer of the upper digestive tract in children CGDP and its features in HP infection. Methods: A total of 128 children aged 6 to 15 years exhibited CGDP. All patients underwent EGD, with a description of the visible mucous membrane of the stomach and duodenum. Research on HP infection was carried out by two methods: a breath test and an immunochromatographic faecal test. Results: It was noted that the rate of Helicobacter pylori infection was higher in patients with ulcerative lesions of the gastrointestinal tract than in patients with inflammatory processes (on average 1: 0.6). A high prevalence of gastroesophageal and duodenogastric reflux was revealed in patients with HP infection. In children with HP infection, atrophic lesions of the antrum and body of the stomach, bulbar and distal duodenum prevailed. Conclusions: Gastric ulcers and duodenal ulcers developed 94% more often in children with HP infection than in HP-uninfected patients (P<0.005), and atrophic changes in the mucous layer of the stomach and intestines were 4 times more common against the background of the more common gastroduodenal (by 77.6%) and duodenogastric (by 67.4%) reflux.
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来源期刊
Biomedical and Biotechnology Research Journal
Biomedical and Biotechnology Research Journal Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
2.20
自引率
42.90%
发文量
24
审稿时长
11 weeks
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