神话和传说:支气管瓣膜在肺气肿的治疗中有作用吗?

Q4 Medicine
A. Lampkin, C. Bellinger
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引用次数: 0

摘要

肺气肿和慢性阻塞性肺疾病是非常普遍的疾病状态。严重肺气肿患者已被证明可以从肺减容手术中获益,但代价是围手术期死亡率增加。在过去的20年里,人们对微创支气管镜下肺减容术的兴趣越来越大,其中支气管内瓣膜(ebv)是研究最多的一种方法。目前,美国食品和药物管理局批准了两种这样的设备:Zephyr和Spiration。在这里,我们回顾了关于EBV放置的文献,强调了以前的试验如何告知瓣膜放置的当前适应症。本文还回顾了ebv的潜在益处和相关并发症。尽管支气管瓣膜已经取得了令人鼓舞的结果,并且是肺减容手术的潜在更安全的替代方法,但需要进一步的指南来改善患者选择和手术效果。误解:在严重肺气肿中,手术切除是肺减容的唯一选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Myths and Legends: Do Bronchial Valves Have a Role in the Management of Emphysema?
Emphysema and chronic obstructive pulmonary disease are highly prevalent disease states. Patients with severe emphysematous disease have been shown to benefit from lung volume reduction surgery, at the cost of increased perioperative mortality. Interest in minimally invasive bronchoscopic lung volume reduction has increased over the past 2 decades, with endobronchial valves (EBVs) being the most studied of these modalities. Currently, there are 2 such devices that are US Food and Drug Administration approved, Zephyr and Spiration. Here, we have reviewed the literature with regard to EBV placement, highlighting how previous trials have informed current indications for valve placement. This article also reviews the potential benefits of EBVs and the associated complications. Although bronchial valves have yielded promising results and are a potentially safer alternative to lung volume reduction surgery, further guidelines are needed to improve patient selection and procedure performance. Myth: In severe emphysema, surgical resection is the only option for lung volume reduction.
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来源期刊
Clinical Pulmonary Medicine
Clinical Pulmonary Medicine Medicine-Critical Care and Intensive Care Medicine
自引率
0.00%
发文量
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期刊介绍: Clinical Pulmonary Medicine provides a forum for the discussion of important new knowledge in the field of pulmonary medicine that is of interest and relevance to the practitioner. This goal is achieved through mini-reviews on focused sub-specialty topics in areas covered within the journal. These areas include: Obstructive Airways Disease; Respiratory Infections; Interstitial, Inflammatory, and Occupational Diseases; Clinical Practice Management; Critical Care/Respiratory Care; Colleagues in Respiratory Medicine; and Topics in Respiratory Medicine.
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