异位性皮炎患者的奇异果过敏- ALEX2多重检查特异性IgE结果分析。乳胶果综合征

IF 1.7 3区农林科学 Q3 CHEMISTRY, APPLIED

Food and Agricultural Immunology Pub Date : 2022-07-08 DOI:10.1080/09540105.2022.2095985

J. Čelakovská, E. Čermáková, R. Vankova, P. Boudková, C. Andrys, J. Krejsek

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引用次数: 1

摘要

本研究采用ALEX2过敏探索者试验分析了特应性皮炎患者对猕猴桃过敏原的致敏情况。对乳胶果综合征患者对乳胶、香蕉、鳄梨、花粉、种子等分子成分的致敏性也进行了评价。对100例特应性皮炎患者进行了调查。在15%的患者中观察到猕猴桃临床反应的发生率;猕猴桃过敏原Act d 1, Act d 2和Act d 10的组合诊断敏感性为33.3%。1例(1%)患者出现乳胶果综合征，结果为Hev b 6.02、pepers a阳性，并在摄入猕猴桃后出现口腔过敏综合征。7%的患者对猕猴桃和乳胶的分子成分都有过敏反应。进一步研究猕猴桃过敏应关注几丁质酶和2S白蛋白的重要性。

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Kiwi allergy in atopic dermatitis patients – analysis of specific IgE results in ALEX2 multiplex examination. Latex fruit syndrome

ABSTRACT Our study analyses the sensitisation profile to kiwi allergens in patients suffering from atopic dermatitis with the use of ALEX2 Allergy Explorer test. The sensitisation to molecular components of latex, banana, avocado, pollen, seeds within latex fruit syndrome was also evaluated. Altogether 100 atopic dermatitis patients were examined. The incidence of clinical reaction to kiwi was observed in 15% of patients; a combination of the kiwi allergens Act d 1, Act d 2 and Act d 10 gave a diagnostic sensitivity of 33.3%. The latex fruit syndrome was recorded in one patient (1%) with the positive result to Hev b 6.02, to (Pers a) and oral allergy syndrome after kiwi ingestion. The sensitisation both to molecular components of kiwi and latex was recorded in 7% of patients. Further research on kiwi allergy should focus on the importance of chitinase and 2S albumins.

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来源期刊

Food and Agricultural Immunology 农林科学-毒理学

CiteScore

5.30

自引率

6.70%

发文量

审稿时长

2 months

期刊介绍： Food and Agricultural Immunology is an international open access journal publishing original immunological research with applications in food, agricultural, environmental and veterinary science. Submissions describing the use of immunological techniques and methods are particularly welcomed. The journal aims to expand our understanding of the interactions at the interface of food and immune systems including studies on: -Development of diagnostic systems – all types of ligand-based assays, e.g. antibody, aptamer -Application of ligand-based assays for the detection or identification of molecules of interest in food science, agricultural research, veterinary investigations and clinical systems relating to food allergy or sensitivity to agricultural chemicals -Effects of food on the immune system -Studies on allergy and allergic reactions -Investigations into food allergies -Development of allergen-free food systems -Development of novel assay formats -Applications of assay systems to the monitoring of food items in relation to safety and labelling -Food quality issues, e.g. speciation, adulteration and contamination -Comparisons between different analytical techniques The journal publishes research and review articles and is essential reading for food scientists, immunologists and all those concerned with the interaction between food and immune systems.