脑老化生物标志物框架:老化生物标志物联盟的共识声明

Life medicine Pub Date : 2023-05-06 eCollection Date: 2023-06-01 DOI:10.1093/lifemedi/lnad017
Yu-Juan Jia, Jun Wang, Jun-Rong Ren, Piu Chan, Shengdi Chen, Xiao-Chun Chen, Jagadish K Chhetri, Junhong Guo, Qihao Guo, Lingjing Jin, Qiang Liu, Qiang Liu, Wenlin Ma, Zhiyong Mao, Moshi Song, Weihong Song, Yi Tang, Difei Wang, Peijun Wang, Lize Xiong, Keqiang Ye, Junjian Zhang, Weiqi Zhang, Xiaoqing Zhang, Yunwu Zhang, Zhanjun Zhang, Zhuohua Zhang, Jialin Zheng, Guang-Hui Liu, Yi Eve Sun, Yan-Jiang Wang, Gang Pei
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引用次数: 0

摘要

中国和世界都面临着严重的人口老龄化和日益加重的老年疾病负担。大脑老化会导致与年龄相关的主要脑部疾病,如神经退行性疾病和中风。识别有效评估大脑衰老的生物标志物,建立大脑衰老评估系统,有助于制定大脑衰老干预策略,有效预防和治疗与衰老相关的脑疾病。因此,衰老生物标志物联盟(ABC)的专家们结合最新的研究结果和实践经验,推荐了大脑衰老的生物标志物,并形成了专家共识,旨在为评估大脑衰老程度和开展大脑衰老相关研究提供依据,最终目的是改善中国和世界老年人的大脑健康。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A framework of biomarkers for brain aging: a consensus statement by the Aging Biomarker Consortium.

China and the world are facing severe population aging and an increasing burden of age-related diseases. Aging of the brain causes major age-related brain diseases, such as neurodegenerative diseases and stroke. Identifying biomarkers for the effective assessment of brain aging and establishing a brain aging assessment system could facilitate the development of brain aging intervention strategies and the effective prevention and treatment of aging-related brain diseases. Thus, experts from the Aging Biomarker Consortium (ABC) have combined the latest research results and practical experience to recommend brain aging biomarkers and form an expert consensus, aiming to provide a basis for assessing the degree of brain aging and conducting brain-aging-related research with the ultimate goal of improving the brain health of elderly individuals in both China and the world.

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