Life medicine

Identification of deferasirox as a human xanthine oxidase inhibitor.

Pub Date : 2025-03-31 DOI: 10.1093/lifemedi/lnaf014 Yunfei Qi, Xinheng He, Xiaoshan Wu, Tingting Zhou, Ningning Liang, Jiazheng Jiao, Yanhao Chen, Yue Yuan, Yuwei Zhang, Yucheng Wang, Yan Liu, Qiurong Ding

A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement.

Pub Date : 2025-03-07 DOI: 10.1093/lifemedi/lnaf011 Xiaolong Fu, Si Wang, Yunhao Wu, Yu Sun, Wenwen Liu, Xin Xi, Geng-Lin Li, Ke Liu, Wei Yuan, Fangyi Chen, Hongyang Wang, Tao Yang, Yuhe Liu, Jialin Zheng, Haibo Shi, Jing Qu, Xiaowei Chen, Limin Suo, Yideng Huang, Xinbo Xu, Xuxia Tang, Xiaojun Li, Lei Xu, Xia Gao, Lisheng Yu, Yilai Shu, Weiqi Zhang, Jinpeng Sun, Huijun Yuan, Shusheng Gong, Wenyan Li, Xiulan Ma, Dingjun Zha, Jiangang Gao, Huawei Li, Zuhong He, Guang-Hui Liu, Gang Pei, Weijia Kong, Haibo Wang, Renjie Chai

Advances and applications of gut organoids: modeling intestinal diseases and therapeutic development.

Pub Date : 2025-03-07 DOI: 10.1093/lifemedi/lnaf012 Xiaoting Xu, Yuping Zhang, Guoxin Huang, Ansu Perekatt, Yan Wang, Lei Chen