德国认知行为疗法和精神分析互动疗法中精神障碍患者的自恋维度和抑郁症状:一项前瞻性队列研究。

IF 30.8 1区 医学 Q1 PSYCHIATRY
Lancet Psychiatry Pub Date : 2023-12-01 Epub Date: 2023-10-13 DOI:10.1016/S2215-0366(23)00293-6
Maike Richter, Simon Mota, Leonie Hater, Rebecca Bratek, Janik Goltermann, Carlotta Barkhau, Marius Gruber, Jonathan Repple, Michael Storck, Rogério Blitz, Dominik Grotegerd, Oliver Masuhr, Ulrich Jaeger, Bernhard T Baune, Martin Dugas, Martin Walter, Udo Dannlowski, Ulrike Buhlmann, Mitja Back, Nils Opel
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引用次数: 1

摘要

背景:自恋型人格特征被认为会对抑郁症状、治疗联盟和治疗结果产生负面影响,即使在没有自恋型人格障碍的情况下也是如此。我们旨在研究在两个跨诊断样本中,钦佩和竞争的维度自恋方面如何影响不同治疗模式的抑郁症状。方法:我们在德国的两个独立成人样本中进行了一项自然主义、观察性前瞻性队列研究:一个样本来自一家住院精神病诊所和一家提供认知行为治疗(CBT)的门诊治疗服务,另一个样本则来自一家提供精神分析互动治疗(PIT)的住院诊所。接受CBT治疗的住院患者有情感或精神障碍。对于另外两个站点,收集了所有服务用户的数据。在接受CBT和PIT治疗的患者中,我们研究了核心自恋及其方面的钦佩和竞争对抑郁症状的影响,这些影响通过自恋钦佩和竞争问卷简版进行测量,通过Beck抑郁量表和患者健康问卷抑郁量表进行测量。主要分析是回归模型,从核心自恋及其方面预测基线和治疗后抑郁的严重程度。在门诊CBT组中进行中介分析,以了解治疗联盟对治疗后自恋与抑郁严重程度之间关系的影响。研究结果:样本包括2371名患者(1423[60%]女性和948[40%]男性;平均年龄33.13岁[SD13.19;范围18-81),CBT组有517名住院患者和1052名门诊患者,PIT组有802名住院患者。未收集种族数据。CBT的平均治疗时间为300天(SD319),PIT为67天(SD26)PIT。在两组患者中,核心自恋都不能预测治疗前抑郁的严重程度,但自恋竞争与基线时更高的抑郁症状负荷相关(CBT为β2.47[95%CI 1.78至3.12],PIT为1.05(0.54至1.55]),自恋钦佩显示出相反的效果(CBT的-2.02[-2.62至1.41],PIT的-0.64[-11.11至0.17])。CBT中的核心自恋(β0.79[0.10~1.47])和自恋竞争(0.89[0.19~1.58])预测治疗反应较差,而钦佩则没有效果。在PIT中,自恋对治疗结果没有明显影响。治疗联盟在门诊CBT样本中介导自恋对治疗后抑郁严重程度的影响。解释:由于自恋会影响CBT治疗前后精神障碍的抑郁严重程度,即使在没有自恋型人格障碍的情况下,在未来的研究和临床常规中也应考虑对自恋进行维度评估。治疗联盟和治疗策略的相关性可用于指导治疗方法。资助:IZKF Münster.翻译:关于摘要的德语翻译,请参阅补充材料部分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Narcissistic dimensions and depressive symptoms in patients across mental disorders in cognitive behavioural therapy and in psychoanalytic interactional therapy in Germany: a prospective cohort study.

Background: Narcissistic personality traits have been theorised to negatively affect depressive symptoms, therapeutic alliance, and treatment outcome, even in the absence of narcissistic personality disorder. We aimed to examine how the dimensional narcissistic facets of admiration and rivalry affect depressive symptoms across treatment modalities in two transdiagnostic samples.

Methods: We did a naturalistic, observational prospective cohort study in two independent adult samples in Germany: one sample pooled from an inpatient psychiatric clinic and an outpatient treatment service offering cognitive behavioural treatment (CBT), and one sample from an inpatient clinic providing psychoanalytic interactional therapy (PIT). Inpatients treated with CBT had an affective or psychotic disorder. For the other two sites, data from all service users were collected. We examined the effect of core narcissism and its facets admiration and rivalry, measured by Narcissistic Admiration and Rivalry Questionnaire-short version, on depressive symptoms, measured by Beck's Depression Inventory and Patient Health Questionnaire-Depression Scale, at baseline and after treatment in patients treated with CBT and PIT. Primary analyses were regression models, predicting baseline and post-treatment depression severity from core narcissism and its facets. Mediation analysis was done in the outpatient CBT group for the effect of the therapeutic alliance on the association between narcissism and depression severity after treatment.

Findings: The sample included 2371 patients (1423 [60·0%] female and 948 [40·0%] male; mean age 33·13 years [SD 13·19; range 18-81), with 517 inpatients and 1052 outpatients in the CBT group, and 802 inpatients in the PIT group. Ethnicity data were not collected. Mean treatment duration was 300 days (SD 319) for CBT and 67 days (SD 26) for PIT. Core narcissism did not predict depression severity before treatment in either group, but narcissistic rivalry was associated with higher depressive symptom load at baseline (β 2·47 [95% CI 1·78 to 3·12] for CBT and 1·05 [0·54 to 1·55] for PIT) and narcissistic admiration showed the opposite effect (-2·02 [-2·62 to -1·41] for CBT and -0·64 [-1·11 to -0·17] for PIT). Poorer treatment response was predicted by core narcissism (β 0·79 [0·10 to 1·47]) and narcissistic rivalry (0·89 [0·19 to 1·58]) in CBT, whereas admiration showed no effect. No effect of narcissism on treatment outcome was discernible in PIT. Therapeutic alliance mediated the effect of narcissism on post-treatment depression severity in the outpatient CBT sample.

Interpretation: As narcissism affects depression severity before and after treatment with CBT across psychiatric disorders, even in the absence of narcissistic personality disorder, the inclusion of dimensional assessments of narcissism should be considered in future research and clinical routines. The relevance of the therapeutic alliance and therapeutic strategy could be used to guide treatment approaches.

Funding: IZKF Münster.

Translation: For the German translation of the abstract see Supplementary Materials section.

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来源期刊
Lancet Psychiatry
Lancet Psychiatry PSYCHIATRY-
CiteScore
58.30
自引率
0.90%
发文量
0
期刊介绍: The Lancet Psychiatry is a globally renowned and trusted resource for groundbreaking research in the field of psychiatry. We specialize in publishing original studies that contribute to transforming and shedding light on important aspects of psychiatric practice. Our comprehensive coverage extends to diverse topics including psychopharmacology, psychotherapy, and psychosocial approaches that address psychiatric disorders throughout the lifespan. We aim to channel innovative treatments and examine the biological research that forms the foundation of such advancements. Our journal also explores novel service delivery methods and promotes fresh perspectives on mental illness, emphasizing the significant contributions of social psychiatry.
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