比较自闭症和神经正常个体的手势频率:一项系统综述和荟萃分析。

IF 4 2区 医学 Q2 CHEMISTRY, MEDICINAL
Nicola McKern, Nicole Dargue, Naomi Sweller
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引用次数: 0

摘要

虽然自闭症的诊断评估通常会筛查手势频率的降低,但支持自闭症手势产生减少的证据并不一致。这项系统综述和荟萃分析旨在阐明自闭症和神经正常个体之间手势频率的差异。纳入的研究比较了自闭症和神经正常个体的手势频率。数据库搜索(APA PsycInfo、ERIC、MEDLINE、ProQuest论文和全球论文)和国际手势研究学会列表服务上未发表数据的呼吁确定了1994年1月至2023年3月的研究。使用Joanna Briggs研究所准实验设计关键评估清单评估研究质量。定量综合包括对所有研究结果的叙述性审查,以及允许根据手势类型进行效果大小计算的文章的荟萃分析。31篇比较701名自闭症患者和860名神经正常患者手势频率的文章被纳入叙事综述,其中25篇也被纳入荟萃分析。荟萃分析发现,与神经正常个体相比,自闭症个体产生的总体、指示和象征性手势明显较少。虽然标志性手势的数量在各组之间似乎是可比较的,但调查标志性手势时,正面和负面效果大小的趋势几乎相同,但大多不显著。手势产生的测量方式、年龄、观察者熟悉程度和任务结构(但不是整体研究质量)调节了效果大小,尽管不同类型的手势不一致。研究结果与自闭症诊断评估中手势使用的特征分析有关,并突出了我们对自闭症手势产生差异的理解差距。(PsycInfo数据库记录(c)2023 APA,保留所有权利)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparing gesture frequency between autistic and neurotypical individuals: A systematic review and meta-analysis.

While diagnostic assessments for autism routinely screen for reduced frequency of gestures, evidence supporting reduced gesture production in autism is inconsistent. This systematic review and meta-analysis aimed to clarify differences in frequency of gestures between autistic and neurotypical individuals. Included studies compared frequency of gestures between autistic and neurotypical individuals. Database searches (APA PsycInfo, ERIC, MEDLINE, ProQuest Dissertations and Theses Global) and a call for unpublished data on the International Society for Gesture Studies listserv identified research from January 1994 to March 2023. Study quality was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Quasi-Experimental Designs. Quantitative synthesis involved a narrative review of all findings and meta-analysis of articles allowing effect size calculations, stratified by the type of gesture. Thirty-one articles comparing frequency of gestures between 701 autistic and 860 neurotypical individuals were included in the narrative review, 25 of which were also included in the meta-analysis. Compared to neurotypical individuals, meta-analyses found that autistic individuals produced significantly less total, deictic, and emblematic gestures. While the number of iconic gestures appeared comparable between groups, studies investigating iconic gestures exhibited an almost equal trend of both positive and negative effect sizes, which were mostly nonsignificant. The way gesture production was measured, age, observer familiarity, and task structure (but not overall study quality) moderated the effect size, albeit inconsistently across the types of gestures. Findings have implications relating to profiling gesture use in diagnostic assessments for autism and highlight gaps in our understanding of differences in gesture production in autism. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

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来源期刊
ACS Infectious Diseases
ACS Infectious Diseases CHEMISTRY, MEDICINALINFECTIOUS DISEASES&nb-INFECTIOUS DISEASES
CiteScore
9.70
自引率
3.80%
发文量
213
期刊介绍: ACS Infectious Diseases will be the first journal to highlight chemistry and its role in this multidisciplinary and collaborative research area. The journal will cover a diverse array of topics including, but not limited to: * Discovery and development of new antimicrobial agents — identified through target- or phenotypic-based approaches as well as compounds that induce synergy with antimicrobials. * Characterization and validation of drug target or pathways — use of single target and genome-wide knockdown and knockouts, biochemical studies, structural biology, new technologies to facilitate characterization and prioritization of potential drug targets. * Mechanism of drug resistance — fundamental research that advances our understanding of resistance; strategies to prevent resistance. * Mechanisms of action — use of genetic, metabolomic, and activity- and affinity-based protein profiling to elucidate the mechanism of action of clinical and experimental antimicrobial agents. * Host-pathogen interactions — tools for studying host-pathogen interactions, cellular biochemistry of hosts and pathogens, and molecular interactions of pathogens with host microbiota. * Small molecule vaccine adjuvants for infectious disease. * Viral and bacterial biochemistry and molecular biology.
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