{"title":"用于超聚焦和定向微磁脑部刺激的平面数字 8 线圈。","authors":"Hongbae Jeong, Jiangdong Deng, Giorgio Bonmassar","doi":"10.1116/6.0001281","DOIUrl":null,"url":null,"abstract":"<p><p>Recently, white-matter fiber tract pathways carrying neural signals through the brain were shown to follow curved, orthogonal grids. This study focuses on how these white-matter fibers may be selectively excited using micromagnetic stimulation (<i>μ</i>MS), a new type of neuronal stimulation, which generates microscopic eddy currents capable of directionally activating neurons. One of the most remarkable properties of this novel type of stimulation is that the <i>μ</i>MS fields provide unique directional activation of neuronal elements not seen with traditional electrical stimulation. An initial prototype built with SU-8 based photolithography technology shows that the structure can be fabricated. The coil design was optimized through electrical resistance calculations and electric field simulations to elicit the brain's maximal focal and directional neural responses.</p>","PeriodicalId":38110,"journal":{"name":"Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516478/pdf/JVTBD9-000039-063202_1.pdf","citationCount":"0","resultStr":"{\"title\":\"Planar figure-8 coils for ultra-focal and directional micromagnetic brain stimulation.\",\"authors\":\"Hongbae Jeong, Jiangdong Deng, Giorgio Bonmassar\",\"doi\":\"10.1116/6.0001281\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Recently, white-matter fiber tract pathways carrying neural signals through the brain were shown to follow curved, orthogonal grids. This study focuses on how these white-matter fibers may be selectively excited using micromagnetic stimulation (<i>μ</i>MS), a new type of neuronal stimulation, which generates microscopic eddy currents capable of directionally activating neurons. One of the most remarkable properties of this novel type of stimulation is that the <i>μ</i>MS fields provide unique directional activation of neuronal elements not seen with traditional electrical stimulation. An initial prototype built with SU-8 based photolithography technology shows that the structure can be fabricated. The coil design was optimized through electrical resistance calculations and electric field simulations to elicit the brain's maximal focal and directional neural responses.</p>\",\"PeriodicalId\":38110,\"journal\":{\"name\":\"Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2021-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516478/pdf/JVTBD9-000039-063202_1.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1116/6.0001281\",\"RegionNum\":4,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/10/13 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"ENGINEERING, ELECTRICAL & ELECTRONIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1116/6.0001281","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/10/13 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
Planar figure-8 coils for ultra-focal and directional micromagnetic brain stimulation.
Recently, white-matter fiber tract pathways carrying neural signals through the brain were shown to follow curved, orthogonal grids. This study focuses on how these white-matter fibers may be selectively excited using micromagnetic stimulation (μMS), a new type of neuronal stimulation, which generates microscopic eddy currents capable of directionally activating neurons. One of the most remarkable properties of this novel type of stimulation is that the μMS fields provide unique directional activation of neuronal elements not seen with traditional electrical stimulation. An initial prototype built with SU-8 based photolithography technology shows that the structure can be fabricated. The coil design was optimized through electrical resistance calculations and electric field simulations to elicit the brain's maximal focal and directional neural responses.