Gergely Tóth-Vajna, Zsombor Tóth-Vajna, Barna Konkoly Thege, Piroska Balog
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The role of depression (assessed by a shortened version of the Beck Depression Inventory) in predicting IC was examined using a binary logistic regression analysis - controlled for sex, age, hypertonia, diabetes, smoking, hypercholesterinemia, hazardous drinking, and body mass index (BMI).</p><p><strong>Results: </strong>The descriptive data indicated that the prevalence of depression was 57.9% in the IC subgroup and 16.1% in those free of IC. The bivariate analyses indicated that hypercholesterinemia, smoking, hazardous drinking, BMI, and depression were significantly associated with IC. Male sex and age showed a trend toward being a significant correlate of IC. Results of the multivariate analyses indicated that depressive symptomatology was significant in predicting IC (OR: 1.08 (1.05-1.11)), even after controlling for lifestyle and traditional risk factors such as smoking, hazardous drinking, and BMI. 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引用次数: 0
摘要
目的:本横断面研究旨在调查抑郁症与间歇性跛行(IC)之间的关系,而不考虑传统的风险因素:样本包括从 33 名全科医生办公室招募的 300 人(平均年龄为 65.3 ± 8.7 岁,61.0% 为女性)。研究人员记录了参与者的病史和是否存在主要心血管风险因素。参与者填写了爱丁堡跛行问卷。采用二元逻辑回归分析法研究了抑郁症(通过贝克抑郁量表的简易版进行评估)在预测 IC 方面的作用,并对性别、年龄、高血压、糖尿病、吸烟、高胆固醇血症、酗酒和体重指数(BMI)进行了控制:描述性数据显示,在 IC 亚组中,抑郁症的患病率为 57.9%,而在无 IC 的患者中,抑郁症的患病率为 16.1%。双变量分析表明,高胆固醇血症、吸烟、酗酒、体重指数和抑郁与 IC 显著相关。男性性别和年龄显示出与集成电路显著相关的趋势。多变量分析结果表明,即使在控制了生活方式和传统风险因素(如吸烟、有害饮酒和体重指数)后,抑郁症状仍可显著预测 IC(OR:1.08(1.05-1.11))。在传统风险因素中,吸烟(OR:2.44 (1.26-4.74))、酗酒(OR:1.19 (1.02-1.40))和高胆固醇血症(OR:2.17 (1.26-3.75))与 IC 呈显著的正相关关系:这些结果表明,在为 IC 患者提供护理时,必须采用多学科方法,重点支持与健康相关的行为改变并控制心理健康症状。
Depression among predictors of intermittent claudication: A cross-sectional study.
Purpose: The aim of the present cross-sectional study was to investigate the relationship between depression and intermittent claudication (IC), independently of traditional risk factors.
Main methods: The sample consisted of 300 individuals (M age = 65.3 ± 8.7 years, 61.0% female) recruited from the offices of 33 general practitioners. Participants' medical history and the presence of major cardiovascular risk factors were recorded. Participants completed the Edinburgh Claudication Questionnaire. The role of depression (assessed by a shortened version of the Beck Depression Inventory) in predicting IC was examined using a binary logistic regression analysis - controlled for sex, age, hypertonia, diabetes, smoking, hypercholesterinemia, hazardous drinking, and body mass index (BMI).
Results: The descriptive data indicated that the prevalence of depression was 57.9% in the IC subgroup and 16.1% in those free of IC. The bivariate analyses indicated that hypercholesterinemia, smoking, hazardous drinking, BMI, and depression were significantly associated with IC. Male sex and age showed a trend toward being a significant correlate of IC. Results of the multivariate analyses indicated that depressive symptomatology was significant in predicting IC (OR: 1.08 (1.05-1.11)), even after controlling for lifestyle and traditional risk factors such as smoking, hazardous drinking, and BMI. Among traditional risk factors, smoking (OR: 2.44 (1.26-4.74)), hazardous drinking (OR: 1.19 (1.02-1.40)), and hypercholesterinemia (OR: 2.17 (1.26-3.75)) showed a significant, positive relationship with IC.
Conclusions: These results underscore the importance of a multidisciplinary approach that focuses on supporting health-related behavioral changes and managing mental health symptoms when providing care for patients with IC.
期刊介绍:
The journal provides a forum for important new research papers written by eminent scientists on experimental medical sciences. Papers reporting on both original work and review articles in the fields of basic and clinical physiology, pathophysiology (from the subcellular organization level up to the oranizmic one), as well as related disciplines, including history of physiological sciences, are accepted.