Keisuke Ueda, Soyoung Kim, Deanna J Greene, Kevin J Black
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Correlates and clinical implications of tic suppressibility.
Purpose of review: Tic disorders are common in the pediatric population and are differentiated from other movement disorders by tic suppressibility. Understanding the mechanism of tic suppression may provide new insights to the pathophysiology of tic disorders. This article highlights clinical phenomenology and neuronal correlates of tic suppressibility.
Recent findings: Recent studies suggest that tic suppressibility exists in children shortly after onset of their tics. Moreover, those who are better able to suppress their tics have better tic outcomes. Interoceptive awareness and automatic action inhibition may be involved in tic suppression.
Summary: We illustrate a possible underlying mechanism of tic suppressibility and its clinical correlations and implications. New concepts such as interoceptive awareness and action inhibition may help explain tic disorders. Further study will be useful to fill remaining knowledge gaps.
期刊介绍：
Current Developmental Disorders Reports commissions expert reviews from leading scientists and clinicians in the field of developmental disorders. What makes the journal unique is its focus—coverage of not one but a host of major disorders in the field, ranging from autism, ADHD, and Tourette’s syndrome, to motor disorders such as cerebral palsy and developmental coordination disorder, through to language and reading disorders such as developmental dyslexia. International authorities serve as editorial board members and section editors, and articles from some of the world’s leading researchers will focus on timely and current reviews of the literature in areas spanning the continuum from bench to communities to individuals. Reviews on new scientific discoveries in neurosciences, genetics, and epidemiology, as well as clinical interventions and policy will provide readers with access to new, innovative, and impactful discoveries as they emerge.
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