一种能利用砷而不是磷生长的细菌

IF 44.7 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Science Pub Date : 2010-12-02 DOI:10.1126/science.1197258

Felisa Wolfe-Simon, Jodi Switzer Blum, Thomas R. Kulp, Gwyneth W. Gordon, Shelley E. Hoeft, Jennifer Pett-Ridge, John F. Stolz, Samuel M. Webb, Peter K. Weber, Paul C. W. Davies, Ariel D. Anbar, Ronald S. Oremland

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引用次数: 453

摘要

生命主要由碳、氢、氮、氧、硫和磷元素组成。虽然这六种元素构成了核酸、蛋白质和脂质，从而构成了生命物质的主体，但从理论上讲，元素周期表中的其他一些元素也可能具有相同的功能。在这里，我们描述了一种从加利福尼亚州莫诺湖分离出来的卤单胞菌科 GFAJ-1 菌株，它能够以砷代替磷来维持生长。我们的数据显示，有证据表明通常含有磷酸盐的大分子（尤其是核酸和蛋白质）中存在砷酸盐。一种主要生物元素的交换可能具有深远的进化和地球化学意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus

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A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus

Life is mostly composed of the elements carbon, hydrogen, nitrogen, oxygen, sulfur, and phosphorus. Although these six elements make up nucleic acids, proteins, and lipids and thus the bulk of living matter, it is theoretically possible that some other elements in the periodic table could serve the same functions. Here, we describe a bacterium, strain GFAJ-1 of the Halomonadaceae, isolated from Mono Lake, California, that is able to substitute arsenic for phosphorus to sustain its growth. Our data show evidence for arsenate in macromolecules that normally contain phosphate, most notably nucleic acids and proteins. Exchange of one of the major bio-elements may have profound evolutionary and geochemical importance.

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来源期刊

Science 综合性期刊-综合性期刊

CiteScore

61.10

自引率

0.90%

发文量

审稿时长

2.1 months

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