在我们的图像:CRISPR基因组编辑的伦理。

Q2 Biochemistry, Genetics and Molecular Biology

Biomolecular Concepts Pub Date : 2021-01-29 DOI:10.1515/bmc-2021-0001

Joel C Eissenberg

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引用次数: 5

摘要

基因组编辑技术的出现有望改变人类健康、牲畜和农业，并根除有害物种。这种变革的力量迫切需要审查和解决与工程基因组的创造和释放有关的伦理冲突。在这里，我讨论了在人类基因组编辑根除遗传疾病和基因驱动技术根除人类疾病的动物载体的背景下，围绕变革性CRISPR/ cas9介导的基因组编辑技术的伦理问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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In Our Image: The Ethics of CRISPR Genome Editing.

The advent of genome editing technology promises to transform human health, livestock and agriculture, and to eradicate pest species. This transformative power demands urgent scrutiny and resolution of the ethical conflicts attached to the creation and release of engineered genomes. Here, I discuss the ethics surrounding the transformative CRISPR/Cas9-mediated genome editing technology in the contexts of human genome editing to eradicate genetic disease and of gene drive technology to eradicate animal vectors of human disease.

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来源期刊

Biomolecular Concepts Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

5.30

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： BioMolecular Concepts is a peer-reviewed open access journal fostering the integration of different fields of biomolecular research. The journal aims to provide expert summaries from prominent researchers, and conclusive extensions of research data leading to new and original, testable hypotheses. Aspects of research that can promote related fields, and lead to novel insight into biological mechanisms or potential medical applications are of special interest. Original research articles reporting new data of broad significance are also welcome. Topics: -cellular and molecular biology- genetics and epigenetics- biochemistry- structural biology- neurosciences- developmental biology- molecular medicine- pharmacology- microbiology- plant biology and biotechnology.