气相色谱-离子迁移谱联用法定量测定酒精饮料中的氨基甲酸乙酯

IF 9.8 1区农林科学 Q1 CHEMISTRY, APPLIED

Food Chemistry Pub Date : 2025-10-10 DOI:10.1016/j.foodchem.2025.146710

Xiuqing Zheng, Mengting Huang, Jiaxu Liu, Binwang Yang, Jianna Yu, Wen Liu, Wenshan Li, Guoxing Jing, Wenjie Liu

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引用次数: 0

摘要

氨基甲酸乙酯（EC）是酒精饮料中的致癌物，对人体健康有潜在危害。建立了氨掺杂气相色谱-傅里叶反褶积离子迁移谱法（GC-FDIMS）测定EC的方法。无水MgSO4脱水辅助二氯甲烷萃取酒精饮料中的EC，简化了样品的前处理。采用FD技术建立了IMS系统，提高了分辨率和灵敏度。结果表明，EC的检出限和定量限分别为0.34 ng/mL和1.16 ng/mL。日内精密度和日间精密度的rsd范围为2.72 % ~ 13.74 %，平均回收率为81.93 % ~ 100.58 %。该方法对啤酒、黄酒、黄酒、红酒等多种酒精饮料样品的测定具有灵敏度高、分离速度快、专属性好、成本低等优点。

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Quantitative determination of ethyl carbamate in alcoholic beverages using gas chromatography coupled to ion mobility spectrometer

Ethyl carbamate (EC), a carcinogen in alcoholic beverages, poses a potential hazard to human health. This study developed a gas chromatography-Fourier deconvolution ion mobility spectrometry (GC-FDIMS) method with ammonia dopant for EC quantification. The anhydrous MgSO₄ dehydration-assisted dichloromethane extraction of EC in alcoholic beverages simplified the sample pretreatment. The IMS system was established by the FD technique to improve the resolution and sensitivity. The results showed that the limit of detection (LOD) and limit of quantification (LOQ) for EC were 0.34 ng/mL and 1.16 ng/mL. The RSDs of the intraday precision and interday precision were in the range of 2.72 %–13.74 %, and the average recovery was between 81.93 % and 100.58 %. The developed method exhibited satisfactory quantitative performance for EC in various alcoholic beverage samples (beer, yellow rice wine, rice wine, and red wine) with the advantage of high sensitivity, fast separation, good specificity, and low cost.

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来源期刊

Food Chemistry 工程技术-食品科技

CiteScore

16.30

自引率

10.20%

发文量

3130

审稿时长

122 days

期刊介绍： Food Chemistry publishes original research papers dealing with the advancement of the chemistry and biochemistry of foods or the analytical methods/ approach used. All papers should focus on the novelty of the research carried out.