阿那白成功治疗重度暴发性紫癜。

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2025-10-08 DOI:10.1111/pde.70034

Francesco Zulian, Luca Spiezia, Antonio Amabile, Francesca Tirelli, Alessandra Meneghel

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引用次数: 0

摘要

暴发性紫癜（PF）是一种罕见的，往往是致命的儿童疾病的特点是血管内血栓形成和出血性梗死的皮肤。及时的诊断和治疗对于防止脏器受累，引起弥散性血管内凝血和四肢坏疽至关重要。PF的治疗需要综合治疗，包括潜在感染的治疗、抗凝治疗和抗炎治疗。在这里，我们提出的情况下，儿童与严重PF成功治疗与阿那金那，一种抗il - 1受体单克隆抗体。

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Successful Treatment of Severe Purpura Fulminans With Anakinra.

Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities. The management of PF requires a comprehensive approach, including the treatment of the underlying infection, anticoagulation, and anti-inflammatory therapy. Herein we present the case of a child with severe PF successfully treated with anakinra, an anti-IL1-receptor monoclonal antibody.

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.