{"title":"并非所有的“念珠菌”都是“念珠菌”:光秃中aseomyces (H.W. Anderson) Sugita& M. Takask. 2022甲真菌病和快速诊断的必要性。","authors":"Mirko Benvenuti, Giulia Gasparini, Antonino Torino, Emanuele Claudio Cozzani","doi":"10.1093/femsle/fnaf107","DOIUrl":null,"url":null,"abstract":"<p><p>Onychomycosis is a common nail disorder typically caused by dermatophytes, with Candida species and non-dermatophytic molds being less frequent agents. Nakaseomyces glabratus (formerly Candida glabrata) is a rare cause of nail infections, notable for its intrinsic resistance to azoles and diagnostic challenges. We report a case of chronic nail discoloration, thickening, and fragility initially misdiagnosed as psoriasis. Microscopy and culture, followed by selective medium analysis, confirmed N. glabratus infection. This case emphasizes the importance of considering uncommon yeast species and highlights both the need for accurate identification to guide therapy and the possible misdiagnosis with other pathologies. Awareness and proper diagnostic approaches are essential for timely and effective management of such rare fungal nail infections.</p>","PeriodicalId":12214,"journal":{"name":"Fems Microbiology Letters","volume":" ","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Not all \\\"Candida\\\" are \\\"Candida\\\": Nakaseomyces glabratus (H.W. Anderson) Sugita& M. Takask. 2022 onychomycosis and the need for rapid diagnostic.\",\"authors\":\"Mirko Benvenuti, Giulia Gasparini, Antonino Torino, Emanuele Claudio Cozzani\",\"doi\":\"10.1093/femsle/fnaf107\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Onychomycosis is a common nail disorder typically caused by dermatophytes, with Candida species and non-dermatophytic molds being less frequent agents. Nakaseomyces glabratus (formerly Candida glabrata) is a rare cause of nail infections, notable for its intrinsic resistance to azoles and diagnostic challenges. We report a case of chronic nail discoloration, thickening, and fragility initially misdiagnosed as psoriasis. Microscopy and culture, followed by selective medium analysis, confirmed N. glabratus infection. This case emphasizes the importance of considering uncommon yeast species and highlights both the need for accurate identification to guide therapy and the possible misdiagnosis with other pathologies. Awareness and proper diagnostic approaches are essential for timely and effective management of such rare fungal nail infections.</p>\",\"PeriodicalId\":12214,\"journal\":{\"name\":\"Fems Microbiology Letters\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-10-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Fems Microbiology Letters\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1093/femsle/fnaf107\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fems Microbiology Letters","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1093/femsle/fnaf107","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
Not all "Candida" are "Candida": Nakaseomyces glabratus (H.W. Anderson) Sugita& M. Takask. 2022 onychomycosis and the need for rapid diagnostic.
Onychomycosis is a common nail disorder typically caused by dermatophytes, with Candida species and non-dermatophytic molds being less frequent agents. Nakaseomyces glabratus (formerly Candida glabrata) is a rare cause of nail infections, notable for its intrinsic resistance to azoles and diagnostic challenges. We report a case of chronic nail discoloration, thickening, and fragility initially misdiagnosed as psoriasis. Microscopy and culture, followed by selective medium analysis, confirmed N. glabratus infection. This case emphasizes the importance of considering uncommon yeast species and highlights both the need for accurate identification to guide therapy and the possible misdiagnosis with other pathologies. Awareness and proper diagnostic approaches are essential for timely and effective management of such rare fungal nail infections.
期刊介绍:
FEMS Microbiology Letters gives priority to concise papers that merit rapid publication by virtue of their originality, general interest and contribution to new developments in microbiology. All aspects of microbiology, including virology, are covered.
2019 Impact Factor: 1.987, Journal Citation Reports (Source Clarivate, 2020)
Ranking: 98/135 (Microbiology)
The journal is divided into eight Sections:
Physiology and Biochemistry (including genetics, molecular biology and ‘omic’ studies)
Food Microbiology (from food production and biotechnology to spoilage and food borne pathogens)
Biotechnology and Synthetic Biology
Pathogens and Pathogenicity (including medical, veterinary, plant and insect pathogens – particularly those relating to food security – with the exception of viruses)
Environmental Microbiology (including ecophysiology, ecogenomics and meta-omic studies)
Virology (viruses infecting any organism, including Bacteria and Archaea)
Taxonomy and Systematics (for publication of novel taxa, taxonomic reclassifications and reviews of a taxonomic nature)
Professional Development (including education, training, CPD, research assessment frameworks, research and publication metrics, best-practice, careers and history of microbiology)
If you are unsure which Section is most appropriate for your manuscript, for example in the case of transdisciplinary studies, we recommend that you contact the Editor-In-Chief by email prior to submission. Our scope includes any type of microorganism - all members of the Bacteria and the Archaea and microbial members of the Eukarya (yeasts, filamentous fungi, microbial algae, protozoa, oomycetes, myxomycetes, etc.) as well as all viruses.