基于混合深度学习技术的多模态生物医学图像早期预测和风险分析。

IF 2.3 4区 医学 Q2 DEVELOPMENTAL BIOLOGY
Anoop Vylala, Bipin Plakkottu Radhakrishnan, Anoop Balakrishnan Kadan
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引用次数: 0

摘要

医学影像在诊断和治疗各种健康状况中起着关键作用,特别是在早期癌症检测中。尽管成像技术取得了进步,但多模态医学图像(如MRI和CT扫描)的复杂性和可变性给准确诊断带来了挑战。传统的方法往往难以有效地结合这些异构数据源,从而限制了为早期癌症检测提供及时和精确预测的能力。本研究提出了一种混合深度学习框架,该框架集成了多模态图像融合技术,以改善早期癌症预测。本工作的主要目标是开发一种高效的模型,可以处理各种医学图像,提取有意义的特征,并为识别癌症区域提供准确的分类。采用的技术包括用于图像预处理的高斯平滑,用于手工特征的ORB (Oriented FAST和rotating BRIEF)特征提取,以及用于基于深度学习的特征提取的InceptionV4网络。最后阶段涉及使用稀疏逻辑回归和MS-GWNN分类器进行分类,旨在预测肿瘤的恶性分期。实验结果表明,该方法的分类准确率为93.4%,灵敏度为91.8%,特异性为92.5%,显著优于传统方法。这些指标在早期发现和风险评估方面表现优异,特别是在高风险癌症病例方面。该模型使用TCIA数据集进行了验证,并显示出强大的融合能力,从而实现了高质量和可靠的预测。未来的工作将探索其他成像模式的整合,临床设置的实时应用,以及融合策略的优化。此外,引入可解释性人工智能(XAI)可以提高模型的可解释性,增强其在临床实践中的可用性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Early Prediction and Risk Analysis Using Hybrid Deep Learning Techniques in Multimodal Biomedical Image

Early Prediction and Risk Analysis Using Hybrid Deep Learning Techniques in Multimodal Biomedical Image

Medical imaging plays a pivotal role in diagnosing and treating various health conditions, especially in early-stage cancer detection. Despite advancements in imaging techniques, the complexity and variability of multimodal medical images, such as MRI and CT scans, pose challenges for accurate diagnosis. Traditional methods often struggle with combining these heterogeneous data sources effectively, limiting the ability to provide timely and precise predictions for early cancer detection. This study proposes a hybrid deep learning framework that integrates multimodal image fusion techniques to improve early cancer prediction. The primary objective of this work is to develop an efficient model that can process diverse medical images, extract meaningful features, and provide accurate classifications for identifying cancerous regions. The techniques employed include Gaussian smoothing for image pre-processing, feature extraction using ORB (Oriented FAST and Rotated BRIEF) for handcrafted features, and the InceptionV4 network for deep learning-based feature extraction. The final stage involves classification using Sparse Logistic Regression and the MS-GWNN classifier, designed to predict the malignancy stage of tumors. The experimental results demonstrate that the proposed approach significantly outperforms traditional methods, achieving a classification accuracy of 93.4%, sensitivity of 91.8%, and specificity of 92.5%. These metrics show superior performance in early detection and risk assessment, especially for high-risk cancer cases. The model is validated using TCIA dataset and displays robust fusion capabilities, leading to high-quality and reliable predictions. Future work will explore the integration of additional imaging modalities, real-time applications for clinical settings, and optimization of fusion strategies. Furthermore, incorporating explainable AI (XAI) can improve the interpretability of the model, enhancing its usability in clinical practice.

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来源期刊
Developmental Neurobiology
Developmental Neurobiology 生物-发育生物学
CiteScore
6.50
自引率
0.00%
发文量
45
审稿时长
4-8 weeks
期刊介绍: Developmental Neurobiology (previously the Journal of Neurobiology ) publishes original research articles on development, regeneration, repair and plasticity of the nervous system and on the ontogeny of behavior. High quality contributions in these areas are solicited, with an emphasis on experimental as opposed to purely descriptive work. The Journal also will consider manuscripts reporting novel approaches and techniques for the study of the development of the nervous system as well as occasional special issues on topics of significant current interest. We welcome suggestions on possible topics from our readers.
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