Jelle Brouwer, Floor van den Berg, Remco Knooihuizen, Hanneke Loerts, Merel Keijzer
{"title":"语言学习对老年抑郁症患者的非药物干预作用。","authors":"Jelle Brouwer, Floor van den Berg, Remco Knooihuizen, Hanneke Loerts, Merel Keijzer","doi":"10.3390/brainsci15090991","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background:</b> Language learning has been proposed as a non-pharmacological intervention to promote healthy aging. This intervention has not been studied in older adults with a history of depression, who experience high prevalence of cognitive dysfunction. This small-scale study was the first to investigate the potential efficacy of language learning in older adults with (past) depression. <b>Methods:</b> Data on psychosocial well-being, cognitive functioning, and language outcomes were collected in nineteen participants with (past) depression (M = 69.7 years old, SD = 2.9; 79% women, 21% men) and a control group of fifteen older adults without depression in the past 25 years (M = 70.1 years old, SD = 3.8; 60% women, 40% men). Data were collected before, immediately after, and four months after completing a three-month language course. <b>Results:</b> Participants with (past) depression showed significant decreases in apathy, social loneliness, and cognitive failures, and increases in associative memory and global cognition. The control group improved on associative memory and letter-number sequencing. Both groups improved in linguistic self-confidence and lexical access to English, while the group with (past) depression also improved on listening and speaking proficiency. <b>Conclusions:</b> The intervention had limited benefits for cognition and psychosocial well-being, but (longer) group-based learning interventions may build up social and motivational reserves protecting against morbidity. Research with larger samples and a no-training control sample is needed to further support these findings.</p>","PeriodicalId":9095,"journal":{"name":"Brain Sciences","volume":"15 9","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468076/pdf/","citationCount":"0","resultStr":"{\"title\":\"Language Learning as a Non-Pharmacological Intervention in Older Adults with (Past) Depression.\",\"authors\":\"Jelle Brouwer, Floor van den Berg, Remco Knooihuizen, Hanneke Loerts, Merel Keijzer\",\"doi\":\"10.3390/brainsci15090991\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Background:</b> Language learning has been proposed as a non-pharmacological intervention to promote healthy aging. This intervention has not been studied in older adults with a history of depression, who experience high prevalence of cognitive dysfunction. This small-scale study was the first to investigate the potential efficacy of language learning in older adults with (past) depression. <b>Methods:</b> Data on psychosocial well-being, cognitive functioning, and language outcomes were collected in nineteen participants with (past) depression (M = 69.7 years old, SD = 2.9; 79% women, 21% men) and a control group of fifteen older adults without depression in the past 25 years (M = 70.1 years old, SD = 3.8; 60% women, 40% men). Data were collected before, immediately after, and four months after completing a three-month language course. <b>Results:</b> Participants with (past) depression showed significant decreases in apathy, social loneliness, and cognitive failures, and increases in associative memory and global cognition. The control group improved on associative memory and letter-number sequencing. Both groups improved in linguistic self-confidence and lexical access to English, while the group with (past) depression also improved on listening and speaking proficiency. <b>Conclusions:</b> The intervention had limited benefits for cognition and psychosocial well-being, but (longer) group-based learning interventions may build up social and motivational reserves protecting against morbidity. Research with larger samples and a no-training control sample is needed to further support these findings.</p>\",\"PeriodicalId\":9095,\"journal\":{\"name\":\"Brain Sciences\",\"volume\":\"15 9\",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468076/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brain Sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/brainsci15090991\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/brainsci15090991","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Language Learning as a Non-Pharmacological Intervention in Older Adults with (Past) Depression.
Background: Language learning has been proposed as a non-pharmacological intervention to promote healthy aging. This intervention has not been studied in older adults with a history of depression, who experience high prevalence of cognitive dysfunction. This small-scale study was the first to investigate the potential efficacy of language learning in older adults with (past) depression. Methods: Data on psychosocial well-being, cognitive functioning, and language outcomes were collected in nineteen participants with (past) depression (M = 69.7 years old, SD = 2.9; 79% women, 21% men) and a control group of fifteen older adults without depression in the past 25 years (M = 70.1 years old, SD = 3.8; 60% women, 40% men). Data were collected before, immediately after, and four months after completing a three-month language course. Results: Participants with (past) depression showed significant decreases in apathy, social loneliness, and cognitive failures, and increases in associative memory and global cognition. The control group improved on associative memory and letter-number sequencing. Both groups improved in linguistic self-confidence and lexical access to English, while the group with (past) depression also improved on listening and speaking proficiency. Conclusions: The intervention had limited benefits for cognition and psychosocial well-being, but (longer) group-based learning interventions may build up social and motivational reserves protecting against morbidity. Research with larger samples and a no-training control sample is needed to further support these findings.
期刊介绍:
Brain Sciences (ISSN 2076-3425) is a peer-reviewed scientific journal that publishes original articles, critical reviews, research notes and short communications in the areas of cognitive neuroscience, developmental neuroscience, molecular and cellular neuroscience, neural engineering, neuroimaging, neurolinguistics, neuropathy, systems neuroscience, and theoretical and computational neuroscience. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.