转基因生物检测分析方法的最低性能要求：数字PCR的补充和新基因组技术和转基因动物检测的建议

IF 1.7 3区农林科学 Q4 FOOD SCIENCE & TECHNOLOGY

Journal of Consumer Protection and Food Safety Pub Date : 2025-03-05 DOI:10.1007/s00003-025-01555-7

Christopher Weidner, Kathrin Lieske, Emilie Dagand, Francesco Gatto, Christian Savini, Wim Broothaerts, Marco Mazzara, Joachim Mankertz

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引用次数: 0

摘要

欧洲转基因实验室网络（ENGL）和欧盟转基因食品和饲料参考实验室（EURL GMFF）的方法性能要求工作组（WG-MPR）扩大了其关于“转基因生物检测分析方法最低性能要求定义”的指导文件的范围。本文件建立了开发和验证转基因分析方法的标准，既适用于欧盟市场授权申请，也适用于官方食品和饲料控制。该指南概述了用于检测和量化转基因生物的方法的定义和性能要求，最近已扩大到包括数字PCR方法、转基因动物的检测以及使用新诱变技术开发的产品的分析。该指导文件可在EURL GMFF网站（https://publications.jrc.ec.europa）免费获取。eu/repository/handle/JRC125975 access 25.02.2025)。

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Minimum performance requirements for analytical methods of GMO testing: supplement on digital PCR and recommendations for detection of new genomics techniques and GM animals

The Working Group on Method Performance Requirements (WG-MPR) of the European Network of GMO Laboratories (ENGL) and the EU Reference Laboratory for Genetically Modified Food and Feed (EURL GMFF) have extended the scope of its guidance document on the “Definition of minimum performance requirements for analytical methods of GMO testing”. This document establishes criteria for the development and validation of methods for GMO analysis, both for EU market authorization applications and for official food and feed control. The guidance outlines definitions and performance requirements for methods used to detect and quantify GMOs and has recently been expanded to include digital PCR methods, the detection of genetically modified animals, and the analysis of products developed using new mutagenesis techniques. The guidance document is freely available on the EURL GMFF website (https://publications.jrc.ec.europa.eu/repository/handle/JRC125975 accessed 25.02.2025).

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来源期刊

Journal of Consumer Protection and Food Safety Veterinary-Food Animals

CiteScore

3.70

自引率

4.20%

发文量

审稿时长

>12 weeks

期刊介绍： The JCF publishes peer-reviewed original Research Articles and Opinions that are of direct importance to Food and Feed Safety. This includes Food Packaging, Consumer Products as well as Plant Protection Products, Food Microbiology, Veterinary Drugs, Animal Welfare and Genetic Engineering. All peer-reviewed articles that are published should be devoted to improve Consumer Health Protection. Reviews and discussions are welcomed that address legal and/or regulatory decisions with respect to risk assessment and management of Food and Feed Safety issues on a scientific basis. It addresses an international readership of scientists, risk assessors and managers, and other professionals active in the field of Food and Feed Safety and Consumer Health Protection. Manuscripts – preferably written in English but also in German – are published as Research Articles, Reviews, Methods and Short Communications and should cover aspects including, but not limited to: · Factors influencing Food and Feed Safety · Factors influencing Consumer Health Protection · Factors influencing Consumer Behavior · Exposure science related to Risk Assessment and Risk Management · Regulatory aspects related to Food and Feed Safety, Food Packaging, Consumer Products, Plant Protection Products, Food Microbiology, Veterinary Drugs, Animal Welfare and Genetic Engineering · Analytical methods and method validation related to food control and food processing. The JCF also presents important News, as well as Announcements and Reports about administrative surveillance.