脑室内出血对早产儿脑干听觉功能的影响

IF 1.3 4区医学 Q4 CLINICAL NEUROLOGY

Brain & Development Pub Date : 2025-09-25 DOI:10.1016/j.braindev.2025.104455

Ze Dong Jiang , Jin Wang , Cui Wang

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引用次数: 0

摘要

目的尚不清楚早产儿脑室内出血（IVH）是否影响脑干听觉通路。本研究探讨IVH早产儿该通路的功能状态，以评估IVH对该通路的影响。方法采用脑干听觉诱发反应（BAER）对83例有IVH或无IVH早产儿和35例正常足月对照进行足月等值年龄时脑干听觉诱发反应（BAER）的研究，并在不同组间检测IVH早产儿的异常情况。结果与正常足月组比较，早产IVH组BAER阈值升高（p < 0.01）。IVH组BAER波潜伏期中度延长，III波和V波振幅显著降低（p < 0.05，和0.05）。与年龄匹配的非IVH组相比，IVH组表现出中度较高的BAER阈值和相对较短的波V潜伏期。但IVH组I-V间期明显短于非IVH组（p < 0.05）。IVH组BAER波振幅小于非IVH组，其中ⅲ波振幅差异有统计学意义（p < 0.05）。结论首次针对IVH的BAER研究表明，IVH早产儿与听力阈值中度升高和脑干听觉传导缩短有关。IVH对早产儿脑干听觉功能的影响。

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The impact of intraventricular hemorrhage on brainstem auditory function in preterm babies

Objective

Whether intraventricular hemorrhage (IVH) in preterm babies affects the brainstem auditory pathway is undetermined. This study investigated the functional status of the pathway in preterm babies with IVH to assess the effect of IVH on the pathway.

Methods

Brainstem auditory evoked response (BAER) was studied at term equivalent age in 83 preterm babies with or without IVH and 35 normal term controls, and between different groups of babies to detect any abnormality in preterm IVH babies.

Results

Compared to the normal term group, the preterm IVH group manifested an elevated BAER threshold (p < 0.01). The IVH group also manifested moderate prolongation in BAER wave latencies and significant reduction in waves III and V amplitudes (p < 0.05, and 0.05). Compared to the age-matched non-IVH group, the IVH group manifested a moderately higher BAER threshold and relatively shorter wave V latency. However, the I-V interval in the IVH group was significantly shorter than in the non-IVH group (p < 0.05). The amplitudes of BAER waves in the IVH group were smaller than in the non-IVH group, and the differences were significant for wave III amplitude (p < 0.05).

Conclusion

This first specific BAER study in IVH revealed that preterm babies with IVH are associated with moderately elevated hearing threshold and shortened brainstem auditory conduction. Brainstem auditory function in preterm babies is affected by IVH.

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来源期刊

Brain & Development 医学-临床神经学

CiteScore

3.60

自引率

0.00%

发文量

153

审稿时长

50 days

期刊介绍： Brain and Development (ISSN 0387-7604) is the Official Journal of the Japanese Society of Child Neurology, and is aimed to promote clinical child neurology and developmental neuroscience. The journal is devoted to publishing Review Articles, Full Length Original Papers, Case Reports and Letters to the Editor in the field of Child Neurology and related sciences. Proceedings of meetings, and professional announcements will be published at the Editor''s discretion. Letters concerning articles published in Brain and Development and other relevant issues are also welcome.