基于石墨烯的仿生神经接口振荡器

IF 5.3 2区 材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY
Konstantin G. Nikolaev, Sergey Grebenchuk, Zhao Jinpei, Kou Yang, Yixin Zhang, Ong Mei Shan, Vitaly Sorokin, Siyu Chen, Qian Wang, Jia Hui Bong, Kostya S. Novoselov, Daria V. Andreeva
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引用次数: 0

摘要

化学振荡器——比如别洛乌索夫-扎博廷斯基反应——长期以来一直被用作研究非平衡化学动力学的模型系统和生物振荡的类似物。然而,许多生物过程依赖于不涉及化学反应的非平衡的、通常是振荡的离子通量。例子包括神经元的动作电位、肌肉收缩、心律、细胞内钙信号和钙波振荡。尽管有这些相似之处,与神经形态界面兼容的仿生系统的发展仍然是一个重大的挑战。本文展示了一种通过开发由氧化石墨烯和聚电解质组成的离子晶体管并将其组装成全离子集成电路来组织振荡离子电流的策略。通过使用外部电压驱动这些系统脱离平衡,各种离子在定义界面上的周期性运动得以实现。这种由离子浓度不平衡引起的局部电场控制的行为,与神经和心脏系统中观察到的生物兴奋性非常相似。这些离子晶体管作为神经形态接口的基础构建块,提供了一个通用平台,以高保真度模拟复杂的生物离子过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Graphene-Based Oscillators for Biomimetic Neuro-Interfaces

Graphene-Based Oscillators for Biomimetic Neuro-Interfaces

Graphene-Based Oscillators for Biomimetic Neuro-Interfaces

Graphene-Based Oscillators for Biomimetic Neuro-Interfaces

Chemical oscillators—such as the Belousov-Zhabotinsky reaction—have long served as model systems for studying non-equilibrium chemical dynamics and as analogues of biological oscillations. However, many biological processes rely on out-of-equilibrium, often oscillatory, ionic fluxes that do not involve chemical reactions. Examples include action potentials in neurons, muscle contraction, cardiac rhythmicity, intracellular calcium signaling, and calcium wave oscillations. Despite these parallels, the development of biomimetic systems compatible with neuromorphic interfaces remains a significant challenge. Here, a strategy is demonstrated to organize oscillating ionic currents by developing ionic transistors composed of graphene oxide and polyelectrolyte, and assembling them into all-ionic integrated circuits. By driving these systems out of equilibrium using external voltages, periodic motion of various ions across defined interfaces is achieved. This behavior, governed by local electric fields arising from unbalanced ionic concentrations, closely mimics biological excitability, such as that observed in neuronal and cardiac systems. These ionic transistors serve as a foundational building block for neuromorphic interfaces, offering a universal platform to emulate complex biological ionic processes with high fidelity.

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来源期刊
Advanced Electronic Materials
Advanced Electronic Materials NANOSCIENCE & NANOTECHNOLOGYMATERIALS SCIE-MATERIALS SCIENCE, MULTIDISCIPLINARY
CiteScore
11.00
自引率
3.20%
发文量
433
期刊介绍: Advanced Electronic Materials is an interdisciplinary forum for peer-reviewed, high-quality, high-impact research in the fields of materials science, physics, and engineering of electronic and magnetic materials. It includes research on physics and physical properties of electronic and magnetic materials, spintronics, electronics, device physics and engineering, micro- and nano-electromechanical systems, and organic electronics, in addition to fundamental research.
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