Emilio Díaz-Moreno, Jose Heredia-Jimenez, Manuel Escabias
{"title":"超越DSM亚型:反对儿童多动症功能差异的神经心理学证据。","authors":"Emilio Díaz-Moreno, Jose Heredia-Jimenez, Manuel Escabias","doi":"10.1080/21622965.2025.2556429","DOIUrl":null,"url":null,"abstract":"<p><p>The diagnostic subtypes of Attention-Deficit/Hyperactivity Disorder (ADHD) described in the DSM-5 remain widely used in clinical practice despite increasing evidence of their instability and questionable neurocognitive validity. This study examined whether the inattentive, hyperactive/impulsive, and combined presentations correspond to distinct cognitive profiles in school-aged children with ADHD. A total of 114 children aged 7-12 years with DSM-5 ADHD diagnoses were assessed with a standardized neuropsychological battery targeting executive functions, working memory, verbal fluency, and sustained attention. Subtypes were classified with the parent-report SNAP-IV. Exclusionary comorbidities were ruled out via structured interviews and a DSM-based screening tool. Between-group comparisons employed Kruskal-Wallis tests and Bayesian ANOVAs, and a k-means cluster analysis identified empirical cognitive profiles independent of subtype labels. Results showed no significant differences in 14 of 15 measures (all <i>p</i> > 0.05). Bayesian analyses provided substantial support for similarity (BF<sub>10</sub> < 0.33; <i>η</i><sup>2</sup> ≤ 0.06), with only phonological fluency showing a modest group effect (H = 9.52, <i>p</i> = 0.009; BF<sub>10</sub> = 3.89; <i>η</i><sup>2</sup> = 0.084). Cluster analysis yielded two stable profiles (low vs. average-high performance) unrelated to DSM-5 subtypes. These findings challenge the clinical utility of symptom-based subtyping in ADHD and support dimensional, performance-based classification models to guide assessment and individualized intervention.</p>","PeriodicalId":8047,"journal":{"name":"Applied Neuropsychology: Child","volume":" ","pages":"1-7"},"PeriodicalIF":1.1000,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Beyond DSM subtypes: Neuropsychological evidence against functional distinctions in childhood ADHD.\",\"authors\":\"Emilio Díaz-Moreno, Jose Heredia-Jimenez, Manuel Escabias\",\"doi\":\"10.1080/21622965.2025.2556429\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The diagnostic subtypes of Attention-Deficit/Hyperactivity Disorder (ADHD) described in the DSM-5 remain widely used in clinical practice despite increasing evidence of their instability and questionable neurocognitive validity. This study examined whether the inattentive, hyperactive/impulsive, and combined presentations correspond to distinct cognitive profiles in school-aged children with ADHD. A total of 114 children aged 7-12 years with DSM-5 ADHD diagnoses were assessed with a standardized neuropsychological battery targeting executive functions, working memory, verbal fluency, and sustained attention. Subtypes were classified with the parent-report SNAP-IV. Exclusionary comorbidities were ruled out via structured interviews and a DSM-based screening tool. Between-group comparisons employed Kruskal-Wallis tests and Bayesian ANOVAs, and a k-means cluster analysis identified empirical cognitive profiles independent of subtype labels. Results showed no significant differences in 14 of 15 measures (all <i>p</i> > 0.05). Bayesian analyses provided substantial support for similarity (BF<sub>10</sub> < 0.33; <i>η</i><sup>2</sup> ≤ 0.06), with only phonological fluency showing a modest group effect (H = 9.52, <i>p</i> = 0.009; BF<sub>10</sub> = 3.89; <i>η</i><sup>2</sup> = 0.084). Cluster analysis yielded two stable profiles (low vs. average-high performance) unrelated to DSM-5 subtypes. These findings challenge the clinical utility of symptom-based subtyping in ADHD and support dimensional, performance-based classification models to guide assessment and individualized intervention.</p>\",\"PeriodicalId\":8047,\"journal\":{\"name\":\"Applied Neuropsychology: Child\",\"volume\":\" \",\"pages\":\"1-7\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Neuropsychology: Child\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://doi.org/10.1080/21622965.2025.2556429\",\"RegionNum\":4,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Neuropsychology: Child","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1080/21622965.2025.2556429","RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Beyond DSM subtypes: Neuropsychological evidence against functional distinctions in childhood ADHD.
The diagnostic subtypes of Attention-Deficit/Hyperactivity Disorder (ADHD) described in the DSM-5 remain widely used in clinical practice despite increasing evidence of their instability and questionable neurocognitive validity. This study examined whether the inattentive, hyperactive/impulsive, and combined presentations correspond to distinct cognitive profiles in school-aged children with ADHD. A total of 114 children aged 7-12 years with DSM-5 ADHD diagnoses were assessed with a standardized neuropsychological battery targeting executive functions, working memory, verbal fluency, and sustained attention. Subtypes were classified with the parent-report SNAP-IV. Exclusionary comorbidities were ruled out via structured interviews and a DSM-based screening tool. Between-group comparisons employed Kruskal-Wallis tests and Bayesian ANOVAs, and a k-means cluster analysis identified empirical cognitive profiles independent of subtype labels. Results showed no significant differences in 14 of 15 measures (all p > 0.05). Bayesian analyses provided substantial support for similarity (BF10 < 0.33; η2 ≤ 0.06), with only phonological fluency showing a modest group effect (H = 9.52, p = 0.009; BF10 = 3.89; η2 = 0.084). Cluster analysis yielded two stable profiles (low vs. average-high performance) unrelated to DSM-5 subtypes. These findings challenge the clinical utility of symptom-based subtyping in ADHD and support dimensional, performance-based classification models to guide assessment and individualized intervention.
期刊介绍:
Applied Neuropsychology: Child publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in children. Full-length articles and brief communications are included. Case studies of child patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.