正面评估组:西班牙健忘轻度认知障碍和阿尔茨海默病样本的信度、效度和判别能力。

IF 1.8 4区 心理学 Q2 PSYCHOLOGY
Luis Heredia, María Marco, Nerea Carrión, Margarita Torrente
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引用次数: 0

摘要

痴呆症是最普遍的神经系统疾病之一,由于其发病率不断上升,是一个重要的健康问题。在各种类型的痴呆症中,阿尔茨海默病(AD)在老年人中最常见,其特征是情景记忆障碍和执行功能下降。轻度认知障碍(MCI)被认为是正常衰老和痴呆之间的过渡阶段,通常被描述为痴呆前期状态。区分这些状态对于患者的发现和适当护理至关重要。功能评估组(FAB)是一种评估执行功能的筛选工具。在这项研究中,36名健康个体(HC)、31名单域遗忘性轻度认知障碍(aMCI)患者和29名阿尔茨海默病(AD)患者在西班牙样本中使用FAB来评估其信度、效度和判别效度。结果表明,AD样品中FAB具有良好的内部一致性(α =。71), aMCI组无明显差异(α = 0.49)。在FAB总分上,HC组与aMCI组、AD组比较差异有统计学意义。FAB在区分HC和患者方面也显示出良好的准确性(AUC = 0.85),估计最佳分界点为16.5。然而,其区分aMCI和AD个体的能力较低(AUC = 0.68)。需要更多的研究来证实我们使用更大样本的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Frontal Assessment Battery: Reliability, validity and discriminative ability in a Spanish sample of amnestic mild cognitive impairment and Alzheimer's disease.

Dementia constitutes one of the most widespread neurological disorders, representing an important health concern due to its increasing prevalence. Among the various types of dementia, Alzheimer's disease (AD) is the most common in the elderly, characterized by episodic memory impairment and also a decline in executive functions. Mild cognitive impairment (MCI) is considered a transitional stage between normal ageing and dementia, often described as a pre-dementia state. Distinguishing between these states is of paramount importance for the detection and appropriate care of patients. Functional Assessment Battery (FAB) is a screening tool for assessing executive function. In this study, 36 healthy individuals (HC), 31 single-domain amnestic mild cognitive impairment (aMCI) patients, and 29 Alzheimer's disease (AD) patients were assessed using FAB to determine its reliability, validity, and discriminative validity in a Spanish sample. Results indicated a good internal consistency of FAB in the AD sample (α = .71), but not in the aMCI group (α = .49). Significant differences between HC and both aMCI and AD groups were observed in the total scores of FAB. The FAB also showed good accuracy in distinguishing between HC and patients (AUC = 0.85), with an estimated optimal cut-off point of 16.5. However, its ability to distinguish between aMCI and AD individuals was lower (AUC = 0.68). More studies are necessary to corroborate our results using larger samples.

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来源期刊
Journal of Neuropsychology
Journal of Neuropsychology 医学-心理学
CiteScore
4.50
自引率
4.50%
发文量
34
审稿时长
>12 weeks
期刊介绍: The Journal of Neuropsychology publishes original contributions to scientific knowledge in neuropsychology including: • clinical and research studies with neurological, psychiatric and psychological patient populations in all age groups • behavioural or pharmacological treatment regimes • cognitive experimentation and neuroimaging • multidisciplinary approach embracing areas such as developmental psychology, neurology, psychiatry, physiology, endocrinology, pharmacology and imaging science The following types of paper are invited: • papers reporting original empirical investigations • theoretical papers; provided that these are sufficiently related to empirical data • review articles, which need not be exhaustive, but which should give an interpretation of the state of research in a given field and, where appropriate, identify its clinical implications • brief reports and comments • case reports • fast-track papers (included in the issue following acceptation) reaction and rebuttals (short reactions to publications in JNP followed by an invited rebuttal of the original authors) • special issues.
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