Jean-Martin Charcot和肌萎缩性侧索硬化症的临床基础:一个历史案例重访。

IF 2.4 4区 医学 Q3 CLINICAL NEUROLOGY
Emmanuel Drouin, Patrick Hautecoeur, Arnaud Kwiatkowski
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引用次数: 0

摘要

我们重温一个具有里程碑意义的临床病例记录的让·马丁·沙科在1877年至1878年,描述了患者的球起病肌萎缩性侧索硬化症(ALS)。该病例为Charcot的观察方法、临床推理和早期神经病理学见解提供了丰富的窗口。我们将讨论Charcot病例分析的方法严谨性,并将其与ALS病理生理学、诊断和护理的现代理解进行对话。这一历史反思突出了19世纪的神经学如何为当前管理神经退行性疾病的多学科方法奠定了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Jean-Martin Charcot and the Clinical Foundations of Amyotrophic Lateral Sclerosis: A Historical Case Revisited.

We revisit a landmark clinical case recorded by Jean-Martin Charcot in 1877-78, describing a patient with bulbar-onset amyotrophic lateral sclerosis (ALS). This case offers a rich window into Charcot's observational method, clinical reasoning, and early neuropathological insights. We discuss the methodological rigor of Charcot's case analysis and place it in dialogue with modern understandings of ALS pathophysiology, diagnosis, and care. This historical reflection highlights how 19th-century neurology laid the foundation for current multidisciplinary approaches to managing neurodegenerative diseases.

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来源期刊
European Neurology
European Neurology 医学-临床神经学
CiteScore
4.40
自引率
4.20%
发文量
51
审稿时长
4-8 weeks
期刊介绍: ''European Neurology'' publishes original papers, reviews and letters to the editor. Papers presented in this journal cover clinical aspects of diseases of the nervous system and muscles, as well as their neuropathological, biochemical, and electrophysiological basis. New diagnostic probes, pharmacological and surgical treatments are evaluated from clinical evidence and basic investigative studies. The journal also features original works and reviews on the history of neurology.
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