{"title":"所有的系统都是：CRISPR串扰增强免疫力。","authors":"Kalani Gast, Rodolphe Barrangou","doi":"10.1016/j.chom.2025.08.002","DOIUrl":null,"url":null,"abstract":"<p><p>In this issue of Cell Host & Microbe, companion manuscripts from Margolis & Meeske<sup>1</sup> and Smith & Fineran<sup>2</sup> demonstrate that CRISPR-Cas systems have an unprecedented level of cooperative crosstalk between different subtypes, which enables primed spacer acquisition. These studies illustrate how CRISPR-Cas systems cooperate to enhance adaptive immunity in bacteria.</p>","PeriodicalId":93926,"journal":{"name":"Cell host & microbe","volume":"33 9","pages":"1470-1472"},"PeriodicalIF":18.7000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"All systems go: CRISPR crosstalk for enhanced immunity.\",\"authors\":\"Kalani Gast, Rodolphe Barrangou\",\"doi\":\"10.1016/j.chom.2025.08.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In this issue of Cell Host & Microbe, companion manuscripts from Margolis & Meeske<sup>1</sup> and Smith & Fineran<sup>2</sup> demonstrate that CRISPR-Cas systems have an unprecedented level of cooperative crosstalk between different subtypes, which enables primed spacer acquisition. These studies illustrate how CRISPR-Cas systems cooperate to enhance adaptive immunity in bacteria.</p>\",\"PeriodicalId\":93926,\"journal\":{\"name\":\"Cell host & microbe\",\"volume\":\"33 9\",\"pages\":\"1470-1472\"},\"PeriodicalIF\":18.7000,\"publicationDate\":\"2025-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell host & microbe\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.chom.2025.08.002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell host & microbe","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.chom.2025.08.002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
All systems go: CRISPR crosstalk for enhanced immunity.
In this issue of Cell Host & Microbe, companion manuscripts from Margolis & Meeske1 and Smith & Fineran2 demonstrate that CRISPR-Cas systems have an unprecedented level of cooperative crosstalk between different subtypes, which enables primed spacer acquisition. These studies illustrate how CRISPR-Cas systems cooperate to enhance adaptive immunity in bacteria.
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