{"title":"肠道细菌帮助大脑换油。","authors":"T Jaymie Connerly, Brittany D Needham","doi":"10.1016/j.chom.2025.08.003","DOIUrl":null,"url":null,"abstract":"<p><p>In this issue, Huang et al. reveal a link between gut bacteria and recovery from brain damage. In a bacteria-dependent manner, a fatty acid \"oil\" improves microglial function through increased peroxisomes. This insight into microglia and their response to gut signals offers targets to explore brain health via gut modulation.</p>","PeriodicalId":93926,"journal":{"name":"Cell host & microbe","volume":"33 9","pages":"1466-1467"},"PeriodicalIF":18.7000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Gut bacteria help the brain with an oil change.\",\"authors\":\"T Jaymie Connerly, Brittany D Needham\",\"doi\":\"10.1016/j.chom.2025.08.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In this issue, Huang et al. reveal a link between gut bacteria and recovery from brain damage. In a bacteria-dependent manner, a fatty acid \\\"oil\\\" improves microglial function through increased peroxisomes. This insight into microglia and their response to gut signals offers targets to explore brain health via gut modulation.</p>\",\"PeriodicalId\":93926,\"journal\":{\"name\":\"Cell host & microbe\",\"volume\":\"33 9\",\"pages\":\"1466-1467\"},\"PeriodicalIF\":18.7000,\"publicationDate\":\"2025-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell host & microbe\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.chom.2025.08.003\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell host & microbe","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.chom.2025.08.003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
In this issue, Huang et al. reveal a link between gut bacteria and recovery from brain damage. In a bacteria-dependent manner, a fatty acid "oil" improves microglial function through increased peroxisomes. This insight into microglia and their response to gut signals offers targets to explore brain health via gut modulation.