Khalid W Freij, Fiona B A T Agbor, Kiari R Kinnie, Vinodh Srinivasasainagendra, Tammie L Quinn, Hemant K Tiwari, Robert E Sorge, Burel R Goodin, Edwin N Aroke
{"title":"慢性腰痛中就业与残疾的生物学、心理和社会影响的探索性研究。","authors":"Khalid W Freij, Fiona B A T Agbor, Kiari R Kinnie, Vinodh Srinivasasainagendra, Tammie L Quinn, Hemant K Tiwari, Robert E Sorge, Burel R Goodin, Edwin N Aroke","doi":"10.1177/01939459251355097","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Chronic low back pain (CLBP) directly causes reduced work productivity and increased absenteeism, disability, and health care costs. However, further research is necessary to identify whether employment correlates with better health outcomes for workers with CLBP.</p><p><strong>Objective: </strong>We aimed to explore differences in biological, psychological, and social variables between individuals with CLBP who have employment and those who receive disability benefits.</p><p><strong>Methods: </strong>This exploratory cross-sectional study used data from adults with nonspecific CLBP (15 employed and 10 receiving disability benefits) who are part of an ongoing study of epigenetics and gene expression signatures of racial and socioeconomic status disparities. Data were collected on depressive symptoms, perceived injustice, internalized stigma, social support, life orientation, pain intensity, pain interference, and various measures of biological aging.</p><p><strong>Results: </strong>On average, unemployed individuals (receiving disability benefits) reported significantly higher levels of internalized stigma of chronic pain (<i>t</i><sub>23</sub> = -2.282, <i>p</i> = .016), pessimism (<i>t</i><sub>23</sub> = -2.646, <i>p</i> = .007), insomnia severity (<i>t</i><sub>23</sub> = -4.201, <i>p</i> < .001), perceived injustice (<i>t</i><sub>23</sub> = -4.108, <i>p</i> < .001), depressive symptoms (<i>t</i><sub>23</sub> = -4.195, <i>p</i> < .001), pain intensity (<i>t</i><sub>23</sub> = -4.195, <i>p</i> < .001), and pain interference (<i>t</i><sub>23</sub> = -5.288, <i>p</i> < .001), but lower pain resilience (<i>t</i><sub>23</sub> = 3.422, <i>p</i> = .001) than participants who were employed. On average, participants receiving disability benefits had GrimAge epigenetic age acceleration, while employed participants had epigenetic age deceleration (<i>t</i><sub>21</sub> = -2.256, <i>p</i> = .017).</p><p><strong>Conclusion: </strong>Among individuals living with CLBP, employment may be associated with a more positive health outcome. To foster an active and healthy workforce, it is essential to understand the biological, psychological, and social factors affecting employment status when addressing CLBP.</p>","PeriodicalId":49365,"journal":{"name":"Western Journal of Nursing Research","volume":" ","pages":"975-986"},"PeriodicalIF":1.7000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An Exploratory Study of the Biological, Psychological, and Social Impact of Employment Versus Disability in Chronic Low Back Pain.\",\"authors\":\"Khalid W Freij, Fiona B A T Agbor, Kiari R Kinnie, Vinodh Srinivasasainagendra, Tammie L Quinn, Hemant K Tiwari, Robert E Sorge, Burel R Goodin, Edwin N Aroke\",\"doi\":\"10.1177/01939459251355097\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Chronic low back pain (CLBP) directly causes reduced work productivity and increased absenteeism, disability, and health care costs. However, further research is necessary to identify whether employment correlates with better health outcomes for workers with CLBP.</p><p><strong>Objective: </strong>We aimed to explore differences in biological, psychological, and social variables between individuals with CLBP who have employment and those who receive disability benefits.</p><p><strong>Methods: </strong>This exploratory cross-sectional study used data from adults with nonspecific CLBP (15 employed and 10 receiving disability benefits) who are part of an ongoing study of epigenetics and gene expression signatures of racial and socioeconomic status disparities. Data were collected on depressive symptoms, perceived injustice, internalized stigma, social support, life orientation, pain intensity, pain interference, and various measures of biological aging.</p><p><strong>Results: </strong>On average, unemployed individuals (receiving disability benefits) reported significantly higher levels of internalized stigma of chronic pain (<i>t</i><sub>23</sub> = -2.282, <i>p</i> = .016), pessimism (<i>t</i><sub>23</sub> = -2.646, <i>p</i> = .007), insomnia severity (<i>t</i><sub>23</sub> = -4.201, <i>p</i> < .001), perceived injustice (<i>t</i><sub>23</sub> = -4.108, <i>p</i> < .001), depressive symptoms (<i>t</i><sub>23</sub> = -4.195, <i>p</i> < .001), pain intensity (<i>t</i><sub>23</sub> = -4.195, <i>p</i> < .001), and pain interference (<i>t</i><sub>23</sub> = -5.288, <i>p</i> < .001), but lower pain resilience (<i>t</i><sub>23</sub> = 3.422, <i>p</i> = .001) than participants who were employed. On average, participants receiving disability benefits had GrimAge epigenetic age acceleration, while employed participants had epigenetic age deceleration (<i>t</i><sub>21</sub> = -2.256, <i>p</i> = .017).</p><p><strong>Conclusion: </strong>Among individuals living with CLBP, employment may be associated with a more positive health outcome. To foster an active and healthy workforce, it is essential to understand the biological, psychological, and social factors affecting employment status when addressing CLBP.</p>\",\"PeriodicalId\":49365,\"journal\":{\"name\":\"Western Journal of Nursing Research\",\"volume\":\" \",\"pages\":\"975-986\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Western Journal of Nursing Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/01939459251355097\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/27 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"NURSING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Western Journal of Nursing Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/01939459251355097","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/27 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"NURSING","Score":null,"Total":0}
引用次数: 0
摘要
背景：慢性腰痛（CLBP）直接导致工作效率降低、缺勤、残疾和医疗费用增加。然而，需要进一步的研究来确定就业是否与CLBP工人更好的健康结果相关。目的：我们旨在探讨有工作的CLBP患者和领取残疾福利的CLBP患者在生物、心理和社会变量方面的差异。方法：本探索性横断面研究使用了非特异性CLBP成人（15名在职和10名领取残疾津贴）的数据，这些数据是正在进行的种族和社会经济地位差异的表观遗传学和基因表达特征研究的一部分。收集了抑郁症状、感知不公、内化耻辱、社会支持、生活取向、疼痛强度、疼痛干扰和各种生物衰老指标的数据。结果：平均而言，失业个体（领取残疾福利）报告的慢性疼痛内化耻辱感水平显著较高(t23 = -2.282, p =。016)，悲观(t23 = -2.646, p =。007),失眠严重程度(t23 = -4.201, p t23 = -4.108, p t23 = -4.195, p t23 = -4.195, p t23 = -5.288, p t23 = 3.422, p =。001)。平均而言，领取残疾津贴的参与者有GrimAge表观遗传年龄加速，而就业参与者有表观遗传年龄减速（t21 = -2.256, p = 0.017）。结论：在患有CLBP的个体中，就业可能与更积极的健康结果相关。为了培养一支积极健康的劳动力队伍，在解决CLBP问题时，了解影响就业状况的生物、心理和社会因素至关重要。
An Exploratory Study of the Biological, Psychological, and Social Impact of Employment Versus Disability in Chronic Low Back Pain.
Background: Chronic low back pain (CLBP) directly causes reduced work productivity and increased absenteeism, disability, and health care costs. However, further research is necessary to identify whether employment correlates with better health outcomes for workers with CLBP.
Objective: We aimed to explore differences in biological, psychological, and social variables between individuals with CLBP who have employment and those who receive disability benefits.
Methods: This exploratory cross-sectional study used data from adults with nonspecific CLBP (15 employed and 10 receiving disability benefits) who are part of an ongoing study of epigenetics and gene expression signatures of racial and socioeconomic status disparities. Data were collected on depressive symptoms, perceived injustice, internalized stigma, social support, life orientation, pain intensity, pain interference, and various measures of biological aging.
Results: On average, unemployed individuals (receiving disability benefits) reported significantly higher levels of internalized stigma of chronic pain (t23 = -2.282, p = .016), pessimism (t23 = -2.646, p = .007), insomnia severity (t23 = -4.201, p < .001), perceived injustice (t23 = -4.108, p < .001), depressive symptoms (t23 = -4.195, p < .001), pain intensity (t23 = -4.195, p < .001), and pain interference (t23 = -5.288, p < .001), but lower pain resilience (t23 = 3.422, p = .001) than participants who were employed. On average, participants receiving disability benefits had GrimAge epigenetic age acceleration, while employed participants had epigenetic age deceleration (t21 = -2.256, p = .017).
Conclusion: Among individuals living with CLBP, employment may be associated with a more positive health outcome. To foster an active and healthy workforce, it is essential to understand the biological, psychological, and social factors affecting employment status when addressing CLBP.
期刊介绍：
Western Journal of Nursing Research (WJNR) is a widely read and respected peer-reviewed journal published twelve times a year providing an innovative forum for nurse researchers, students, and clinical practitioners to participate in ongoing scholarly dialogue. WJNR publishes research reports, systematic reviews, methodology papers, and invited special papers. This journal is a member of the Committee on Publication Ethics (COPE).
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