Melissa Walls , Dane Hautala , Kelley J. Sittner , Andrea Medley , Ravyn Gibbs
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Cumulative probability of lifetime use by age 27 years was 29 % for psychostimulants (e.g., methamphetamine), 35 % for prescription pain pills, and 22 % for heroin. New cases of prescription pain pill misuse peaked in the early 2000s, followed by rapid increases in psychostimulant and heroin use starting around 2008. We found that 37 %–51 % of drug users eventually met criteria for dependence, and progression from use to dependence was typically within one year for this sub-group. Socio-demographic factors were differentially associated with probability of substance use, depending on drug type. Findings highlight the critical need for culturally grounded prevention, harm reduction, and treatment strategies to address substance use inequities in Indigenous communities.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"171 ","pages":"Article 108456"},"PeriodicalIF":3.6000,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A prospective longitudinal analysis of opioid and stimulant use in American Indian and First Nations communities\",\"authors\":\"Melissa Walls , Dane Hautala , Kelley J. Sittner , Andrea Medley , Ravyn Gibbs\",\"doi\":\"10.1016/j.addbeh.2025.108456\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We describe stages of opioid and psychostimulant use (i.e., onset of use and progression to dependence) over the early life course within Indigenous communities where drug overdose impacts have been most extreme. This community-based participatory research includes 9 waves of survey data collected prior to and during the unfolding of the overdose epidemic in North America (2002–2017) on/near 8 distinct American Indian reservations or First Nation reserves. Substance use (psychostimulants, prescription pain pill misuse, and heroin) was assessed via structured diagnostic interviews. Discrete time survival analysis was used to estimate hazard rates for substance use initiation, dependence, and transitions from first use to dependence. Cumulative probability of lifetime use by age 27 years was 29 % for psychostimulants (e.g., methamphetamine), 35 % for prescription pain pills, and 22 % for heroin. New cases of prescription pain pill misuse peaked in the early 2000s, followed by rapid increases in psychostimulant and heroin use starting around 2008. We found that 37 %–51 % of drug users eventually met criteria for dependence, and progression from use to dependence was typically within one year for this sub-group. Socio-demographic factors were differentially associated with probability of substance use, depending on drug type. Findings highlight the critical need for culturally grounded prevention, harm reduction, and treatment strategies to address substance use inequities in Indigenous communities.</div></div>\",\"PeriodicalId\":7155,\"journal\":{\"name\":\"Addictive behaviors\",\"volume\":\"171 \",\"pages\":\"Article 108456\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-08-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Addictive behaviors\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0306460325002175\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PSYCHOLOGY, CLINICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Addictive behaviors","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0306460325002175","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHOLOGY, CLINICAL","Score":null,"Total":0}
A prospective longitudinal analysis of opioid and stimulant use in American Indian and First Nations communities
We describe stages of opioid and psychostimulant use (i.e., onset of use and progression to dependence) over the early life course within Indigenous communities where drug overdose impacts have been most extreme. This community-based participatory research includes 9 waves of survey data collected prior to and during the unfolding of the overdose epidemic in North America (2002–2017) on/near 8 distinct American Indian reservations or First Nation reserves. Substance use (psychostimulants, prescription pain pill misuse, and heroin) was assessed via structured diagnostic interviews. Discrete time survival analysis was used to estimate hazard rates for substance use initiation, dependence, and transitions from first use to dependence. Cumulative probability of lifetime use by age 27 years was 29 % for psychostimulants (e.g., methamphetamine), 35 % for prescription pain pills, and 22 % for heroin. New cases of prescription pain pill misuse peaked in the early 2000s, followed by rapid increases in psychostimulant and heroin use starting around 2008. We found that 37 %–51 % of drug users eventually met criteria for dependence, and progression from use to dependence was typically within one year for this sub-group. Socio-demographic factors were differentially associated with probability of substance use, depending on drug type. Findings highlight the critical need for culturally grounded prevention, harm reduction, and treatment strategies to address substance use inequities in Indigenous communities.
期刊介绍:
Addictive Behaviors is an international peer-reviewed journal publishing high quality human research on addictive behaviors and disorders since 1975. The journal accepts submissions of full-length papers and short communications on substance-related addictions such as the abuse of alcohol, drugs and nicotine, and behavioral addictions involving gambling and technology. We primarily publish behavioral and psychosocial research but our articles span the fields of psychology, sociology, psychiatry, epidemiology, social policy, medicine, pharmacology and neuroscience. While theoretical orientations are diverse, the emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. However, innovative and empirically oriented case studies that might encourage new lines of inquiry are accepted as well. Studies that clearly contribute to current knowledge of etiology, prevention, social policy or treatment are given priority. Scholarly commentaries on topical issues, systematic reviews, and mini reviews are encouraged. We especially welcome multimedia papers that incorporate video or audio components to better display methodology or findings.
Studies can also be submitted to Addictive Behaviors? companion title, the open access journal Addictive Behaviors Reports, which has a particular interest in ''non-traditional'', innovative and empirically-oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research.