CRISPR-TO：空间转录组可编程控制的多功能工具

IF 26.7 1区医学 Q1 NEUROSCIENCES

Nature Reviews Neuroscience Pub Date : 2025-08-11 DOI:10.1038/s41583-025-00958-7

Mengting Han

引用次数: 0

摘要

在这篇贸易工具文章中，韩梦婷讨论了CRISPR-TO的发展，这是一种干扰内源性RNA定位的可编程方法，以及它在神经元空间转录组功能筛选中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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CRISPR-TO: a versatile tool for programmable control of the spatial transcriptome

In this Tools of the Trade article, Mengting Han discusses the development of CRISPR-TO, a programmable method for perturbing endogenous RNA localization, and its use for functional screening of the spatial transcriptome in neurons.

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来源期刊

Nature Reviews Neuroscience NEUROSCIENCES-

自引率

0.60%

发文量

104

期刊介绍： Nature Reviews Neuroscience is a multidisciplinary journal that covers various fields within neuroscience, aiming to offer a comprehensive understanding of the structure and function of the central nervous system. Advances in molecular, developmental, and cognitive neuroscience, facilitated by powerful experimental techniques and theoretical approaches, have made enduring neurobiological questions more accessible. Nature Reviews Neuroscience serves as a reliable and accessible resource, addressing the breadth and depth of modern neuroscience. It acts as an authoritative and engaging reference for scientists interested in all aspects of neuroscience.