{"title":"化学物质转运和转化在人体病理生理生物物理中的作用。","authors":"Kazeem B Olanrewaju, Ashlee N Ford Versypt","doi":"10.1038/s44341-025-00025-3","DOIUrl":null,"url":null,"abstract":"<p><p>This review focuses on the roles of chemical species transport and biochemical and biophysical transformation within the gastrointestinal and immune systems and interactions with tissue structure and biomechanics in the mechanisms of pathophysiological conditions including gastrointestinal reflux disease and allergic responses. Combinations of biophysical and biochemical techniques are needed to unravel the complex interplay between transport and transformation to develop more effective interventions and ultimately improve patient outcomes.</p>","PeriodicalId":501703,"journal":{"name":"npj Biological Physics and Mechanics","volume":"2 1","pages":"20"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328227/pdf/","citationCount":"0","resultStr":"{\"title\":\"Roles of chemical species transport and transformation in the biophysics of human pathophysiology.\",\"authors\":\"Kazeem B Olanrewaju, Ashlee N Ford Versypt\",\"doi\":\"10.1038/s44341-025-00025-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This review focuses on the roles of chemical species transport and biochemical and biophysical transformation within the gastrointestinal and immune systems and interactions with tissue structure and biomechanics in the mechanisms of pathophysiological conditions including gastrointestinal reflux disease and allergic responses. Combinations of biophysical and biochemical techniques are needed to unravel the complex interplay between transport and transformation to develop more effective interventions and ultimately improve patient outcomes.</p>\",\"PeriodicalId\":501703,\"journal\":{\"name\":\"npj Biological Physics and Mechanics\",\"volume\":\"2 1\",\"pages\":\"20\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328227/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"npj Biological Physics and Mechanics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1038/s44341-025-00025-3\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/6 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"npj Biological Physics and Mechanics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s44341-025-00025-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/6 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Roles of chemical species transport and transformation in the biophysics of human pathophysiology.
This review focuses on the roles of chemical species transport and biochemical and biophysical transformation within the gastrointestinal and immune systems and interactions with tissue structure and biomechanics in the mechanisms of pathophysiological conditions including gastrointestinal reflux disease and allergic responses. Combinations of biophysical and biochemical techniques are needed to unravel the complex interplay between transport and transformation to develop more effective interventions and ultimately improve patient outcomes.
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